Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells
Soeda, Akio, Inagaki, Akihito, Oka, Naoki, Ikegame, Yuka, Aoki, Hitomi, Yoshimura, Shin-ichi, Nakashima, Shigeru, Kunisada, Takahiro, Iwama, Toru
Published in The Journal of biological chemistry (18.04.2008)
Published in The Journal of biological chemistry (18.04.2008)
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Journal Article
Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity
Hiraoka, Kei, Inagaki, Akihito, Kato, Yuki, Huang, Tiffany T, Mitchell, Leah A, Kamijima, Shuichi, Takahashi, Masamichi, Matsumoto, Hiroshi, Hacke, Katrin, Kruse, Carol A, Ostertag, Derek, Robbins, Joan M, Gruber, Harry E, Jolly, Douglas J, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2017)
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Therapeutic activity of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer
Inoko, Kazuho, Hiraoka, Kei, Inagaki, Akihito, Takahashi, Mizuna, Kushibiki, Toshihiro, Hontani, Koji, Takano, Hironobu, Sato, Shoki, Takeuchi, Shintaro, Nakamura, Toru, Tsuchikawa, Takahiro, Shichinohe, Toshiaki, Gruber, Harry E, Jolly, Douglas J, Kasahara, Noriyuki, Hirano, Satoshi
Published in Cancer gene therapy (01.08.2018)
Published in Cancer gene therapy (01.08.2018)
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Journal Article
Epithelial Membrane Protein-2 (EMP2) Activates Src Protein and Is a Novel Therapeutic Target for Glioblastoma
Qin, Yu, Fu, Maoyong, Takahashi, Masamichi, Iwanami, Akio, Kuga, Daisuke, Rao, Rajiv G., Sudhakar, Deepthi, Huang, Tiffany, Kiyohara, Meagan, Torres, Kathleen, Dillard, Christen, Inagaki, Akihito, Kasahara, Noriyuki, Goodglick, Lee, Braun, Jonathan, Mischel, Paul S., Gordon, Lynn K., Wadehra, Madhuri
Published in The Journal of biological chemistry (16.05.2014)
Published in The Journal of biological chemistry (16.05.2014)
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Journal Article
PET imaging for gene & cell therapy
Collins, Sara A, Hiraoka, Kei, Inagaki, Akihito, Kasahara, Noriyuki, Tangney, Mark
Published in Current gene therapy (01.02.2012)
Published in Current gene therapy (01.02.2012)
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Journal Article
Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions
Inagaki, Akihito, Soeda, Akio, Oka, Naoki, Kitajima, Hideomi, Nakagawa, Jiro, Motohashi, Tsutomu, Kunisada, Takahiro, Iwama, Toru
Published in Biochemical and biophysical research communications (28.09.2007)
Published in Biochemical and biophysical research communications (28.09.2007)
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Journal Article
EXTH-33. RETROVIRAL REPLICATING VECTORS PSEUDOTYPED WITH GIBBON APE LEUKEMIA VIRUS ENVELOPE FOR PRODRUG ACTIVATOR GENE THERAPY IN PRECLINICAL GLIOMA MODELS
Inagaki, Akihito, Collins, Sara, Freedman, Alicia, Montoya, Megan, Haddad, Alexander, Barcova, Maria, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model
Mitchell, Leah A, Lopez Espinoza, Fernando, Mendoza, Daniel, Kato, Yuki, Inagaki, Akihito, Hiraoka, Kei, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J, Robbins, Joan M
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2017)
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Journal Article
EXTH-44. DEVELOPMENT OF RETROVIRAL REPLICATING VECTORS ENCODING SEQUENCE-OPTIMIZED NITROREDUCTASE FOR PRODRUG ACTIVATOR GENE THERAPY IN HUMAN GLIOMA MODELS
Collins, Sara, Inagaki, Akihito, Tai, Chien-Kuo, Logg, Christopher R, Searle, Peter, Tangney, Mark, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
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IMMU-09. DISSECTING THE INTERPLAY BETWEEN THE ENDOGENOUS IMMUNE RESPONSE AND ONCOLYTIC VIRUS THERAPY IN PEDIATRIC BRAIN TUMORS
Hoare, Owen, Jung, Jangham, Inagaki, Akihito, Yu, Bohyeon, Collins, Sara, Chuntova, Polly, Barcova, Maria, Patel, Trishna, Kasahara, Noriyuki, Müller, Sabine, Diaz, Aaron
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Abstract B03: Development of retroviral replicating vectors expressing codon-optimized nitroreductase for prodrug activator gene therapy in human glioma models
Collins, Sara, Inagaki, Akihito, Tangney, Mark, Kasahara, Noriyuki
Published in Clinical cancer research (01.01.2017)
Published in Clinical cancer research (01.01.2017)
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Therapeutic activity of retroviral replicating vector-mediated gene therapy in combination with anti-PD-1 antibody in a murine pancreatic cancer model
Niwa, Hiroki, Nakamura, Toru, Kushiya, Hiroki, Kuraya, Tomotaka, Inoko, Kazuho, Inagaki, Akihito, Suzuki, Tomohiro, Sasaki, Katsunori, Tsuchikawa, Takahiro, Hiraoka, Kei, Shichinohe, Toshiaki, Hatanaka, Yutaka, Jolly, Douglas J., Kasahara, Noriyuki, Hirano, Satoshi
Published in Cancer gene therapy (01.09.2024)
Published in Cancer gene therapy (01.09.2024)
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Journal Article
THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIOMA AND INTRACEREBELLAR MEDULLOBLASTOMA
Richardson, Angela, Collins, Sara, Inagaki, Akihito, Armstrong, Valerie, Robbins, David, Ayad, Nagi, Gruber, Harry, Jolly, Douglas, Cloughesy, Timothy, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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Journal Article
Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells
Kozlowska, Anna K., Tseng, Han-Ching, Kaur, Kawaljit, Topchyan, Paytsar, Inagaki, Akihito, Bui, Vickie T., Kasahara, Noriyuki, Cacalano, Nicholas, Jewett, Anahid
Published in Cancer Immunology, Immunotherapy (01.09.2016)
Published in Cancer Immunology, Immunotherapy (01.09.2016)
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Journal Article
EXTH-65. INSERTION OF MICRORNA TARGET SEQUENCES INTO RETROVIRAL REPLICATING VECTORS EFFECTIVELY RESTRICTS TRANSGENE EXPRESSION AND VIRAL REPLICATION IN HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS
Collins, Sara, Inagaki, Akihito, Barcova, Maria, Freedman, Alicia, Montoya, Megan, Haddad, Alexander, Hacke, Katrin, Matsuura, Suzanne, Timberlake, Nina, Lin, Amy, Jolly, Douglas, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression
Perez, Omar D, Logg, Christopher R, Hiraoka, Kei, Diago, Oscar, Burnett, Ryan, Inagaki, Akihito, Jolson, Dawn, Amundson, Karin, Buckley, Taylor, Lohse, Dan, Lin, Amy, Burrascano, Cindy, Ibanez, Carlos, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J
Published in Molecular therapy (01.09.2012)
Published in Molecular therapy (01.09.2012)
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Abstract A42: Alternate pseudotypes overcome receptor interference and enable combination suicide gene therapy with retroviral replicating vectors
Grosso, James, Collins, Sara, Inagaki, Akihito, Matsuura, Suzanne, Slomovitz, Brian, Ince, Tan, Kasahara, Noriyuki
Published in Clinical cancer research (01.01.2017)
Published in Clinical cancer research (01.01.2017)
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Journal Article
Retroviral Replicating Vector Toca 511 ( Vocimagene Amiretrorepvec ) for Prodrug Activator Gene Therapy of Lung Cancer
Kushiya, Hiroki, Hiraoka, Kei, Suzuki, Tomohiro, Inoko, Kazuho, Inagaki, Akihito, Niwa, Hiroki, Sasaki, Katsunori, Nakamura, Toru, Tsuchikawa, Takahiro, Shichinohe, Toshiaki, Jolly, Douglas J, Kasahara, Noriyuki, Hirano, Satoshi
Published in Cancers (25.11.2022)
Published in Cancers (25.11.2022)
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Journal Article
STEM-24. THERAPEUTIC APPROACH OF STEM CELL CARRYING RETROVIRAL REPLICATING VECTORS IN HUMAN GLIOMA MODEL
Inagaki, Akihito, Takahashi, Masamichi, Kamijima, Shuichi, Hiraoka, Kei, Tam, Quincy, Faure-Kumar, Emmanuelle, Treger, Janet, Bogan, Brooke, Hacke, Katrin, Collins, Sara, Jolly, Douglas, Kasahara, Noriyuki
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
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