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A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis
Friedman, Scott L., Ratziu, Vlad, Harrison, Stephen A., Abdelmalek, Manal F., Aithal, Guruprasad P., Caballeria, Juan, Francque, Sven, Farrell, Geoffrey, Kowdley, Kris V., Craxi, Antonio, Simon, Krzysztof, Fischer, Laurent, Melchor‐Khan, Liza, Vest, Jeffrey, Wiens, Brian L., Vig, Pamela, Seyedkazemi, Star, Goodman, Zachary, Wong, Vincent Wai‐Sun, Loomba, Rohit, Tacke, Frank, Sanyal, Arun, Lefebvre, Eric
Published in Hepatology (Baltimore, Md.) (01.05.2018)
Published in Hepatology (Baltimore, Md.) (01.05.2018)
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A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study
Yazici, Y., McAlindon, T.E., Fleischmann, R., Gibofsky, A., Lane, N.E., Kivitz, A.J., Skrepnik, N., Armas, E., Swearingen, C.J., DiFrancesco, A., Tambiah, J.R.S., Hood, J., Hochberg, M.C.
Published in Osteoarthritis and cartilage (01.10.2017)
Published in Osteoarthritis and cartilage (01.10.2017)
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A Phase 2A Trial of the Novel mGluR5-Negative Allosteric Modulator Dipraglurant for Levodopa-Induced Dyskinesia in Parkinson's Disease
Tison, François, Keywood, Charlotte, Wakefield, Mark, Durif, Franck, Corvol, Jean-Christophe, Eggert, Karla, Lew, Mark, Isaacson, Stuart, Bezard, Erwan, Poli, Sonia-Maria, Goetz, Christopher G., Trenkwalder, Claudia, Rascol, Olivier
Published in Movement disorders (01.09.2016)
Published in Movement disorders (01.09.2016)
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Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils
Kirchgessner, Todd G., Sleph, Paul, Ostrowski, Jacek, Lupisella, John, Ryan, Carol S., Liu, Xiaoqin, Fernando, Gayani, Grimm, Denise, Shipkova, Petia, Zhang, Rongan, Garcia, Ricardo, Zhu, Jun, He, Aiqing, Malone, Harold, Martin, Richard, Behnia, Kamelia, Wang, Zhaoqing, Barrett, Yu Chen, Garmise, Robert J., Yuan, Long, Zhang, Jane, Gandhi, Mohit D., Wastall, Philip, Li, Tong, Du, Shuyan, Salvador, Lisa, Mohan, Raju, Cantor, Glenn H., Kick, Ellen, Lee, John, Frost, Robert J.A.
Published in Cell metabolism (09.08.2016)
Published in Cell metabolism (09.08.2016)
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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration
Muehlan, Clemens, Boehler, Margaux, Brooks, Sander, Zuiker, Rob, van Gerven, Joop, Dingemanse, Jasper
Published in Journal of psychopharmacology (Oxford) (01.03.2020)
Published in Journal of psychopharmacology (Oxford) (01.03.2020)
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Systematic review: sprue‐like enteropathy associated with olmesartan
Ianiro, G., Bibbò, S., Montalto, M., Ricci, R., Gasbarrini, A., Cammarota, G.
Published in Alimentary pharmacology & therapeutics (01.07.2014)
Published in Alimentary pharmacology & therapeutics (01.07.2014)
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Efficacy of Sofosbuvir and Daclatasvir in Patients With Fibrosing Cholestatic Hepatitis C After Liver Transplantation
Leroy, Vincent, Dumortier, Jérôme, Coilly, Audrey, Sebagh, Mylène, Fougerou-Leurent, Claire, Radenne, Sylvie, Botta, Danielle, Durand, François, Silvain, Christine, Lebray, Pascal, Houssel-Debry, Pauline, Kamar, Nassim, D’Alteroche, Louis, Petrov-Sanchez, Ventzislava, Diallo, Alpha, Pageaux, Georges-Philippe, Duclos-Vallee, Jean-Charles, Pageaux, Georges-Philippe, Duclos-Vallée, Jean-Charles, Coilly, Audrey, Bellissant, Eric, Botta-Fridlund, Danielle, Diallo, Alpha, Dumortier, Jérôme, Durand, François, Duvoux, Christophe, Fougerou-Leurent, Claire, Leroy, Vincent, Petrov-Sanchez, Ventzislava, Renault, Alain, Rohel, Alexandra, Roque, Anne-Marie, Taburet, Anne-Marie, Veislinger, Aurélie
Published in Clinical gastroenterology and hepatology (01.11.2015)
Published in Clinical gastroenterology and hepatology (01.11.2015)
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Safety of long-term denosumab therapy: results from the open label extension phase of two phase 3 studies in patients with metastatic breast and prostate cancer
Stopeck, Alison T., Fizazi, Karim, Body, Jean-Jacques, Brown, Janet E., Carducci, Michael, Diel, Ingo, Fujiwara, Yasuhiro, Martín, Miguel, Paterson, Alexander, Tonkin, Katia, Shore, Neal, Sieber, Paul, Kueppers, Frank, Karsh, Lawrence, Yardley, Denise, Wang, Huei, Maniar, Tapan, Arellano, Jorge, Braun, Ada
Published in Supportive care in cancer (01.01.2016)
Published in Supportive care in cancer (01.01.2016)
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Phase-1 study of vamotinib (PF-114), a 3rd generation BCR::ABL1 tyrosine kinase-inhibitor, in chronic myeloid leukaemia
Turkina, Anna, Vinogradova, Olga, Lomaia, Elza, Shatokhina, Evgeniya, Shukhov, Oleg, Chelysheva, Ekaterina, Shikhbabaeva, Dzhariyat, Nemchenko, Irina, Petrova, Anna, Bykova, Anastasiya, Siordiya, Nadiya, Shuvaev, Vasily, Mikhailov, Ilya, Novikov, Fedor, Shulgina, Veronika, Hochhaus, Andreas, Ottmann, Oliver, Cortes, Jorge, Gale, Robert Peter, Chilov, Ghermes
Published in Annals of hematology (01.05.2025)
Published in Annals of hematology (01.05.2025)
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Skeletal Histomorphometry in Subjects on Teriparatide or Zoledronic Acid Therapy (SHOTZ) Study: A Randomized Controlled Trial
Dempster, David W., Zhou, Hua, Recker, Robert R., Brown, Jacques P., Bolognese, Michael A., Recknor, Christopher P., Kendler, David L., Lewiecki, E. Michael, Hanley, David A., Rao, D. Sudhaker, Miller, Paul D., Woodson, Grattan C., Lindsay, Robert, Binkley, Neil, Wan, Xiaohai, Ruff, Valerie A., Janos, Boris, Taylor, Kathleen A.
Published in The journal of clinical endocrinology and metabolism (01.08.2012)
Published in The journal of clinical endocrinology and metabolism (01.08.2012)
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Efficacy and safety of once-yearly zoledronic acid in Japanese patients with primary osteoporosis: two-year results from a randomized placebo-controlled double-blind study (ZOledroNate treatment in Efficacy to osteoporosis; ZONE study)
Nakamura, T., Fukunaga, M., Nakano, T., Kishimoto, H., Ito, M., Hagino, H., Sone, T., Taguchi, A., Tanaka, S., Ohashi, M., Ota, Y., Shiraki, M.
Published in Osteoporosis international (01.01.2017)
Published in Osteoporosis international (01.01.2017)
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Safety, Tolerability and Pharmacokinetics of Single Ascending and Multiple Oral Doses of Tegoprazan in Healthy Chinese Subjects
He, Jinjie, Cao, Guoying, Yu, Jicheng, Wang, Jingjing, Cheng, Nengneng, Wu, Jufang, Zhang, Jing, Wu, Xiaojie, Zhang, Basheng, Lu, Jiayan, Chen, Shangzhi
Published in Clinical drug investigation (01.01.2021)
Published in Clinical drug investigation (01.01.2021)
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A First-in-Human Randomized, Double-Blind, Placebo-Controlled, Single- and Multiple-Ascending Oral Dose Study of Novel Imidazolopiperazine KAF156 To Assess Its Safety, Tolerability, and Pharmacokinetics in Healthy Adult Volunteers
Leong, F. Joel, Zhao, Rong, Zeng, Shuqi, Magnusson, Baldur, Diagana, Thierry T., Pertel, Peter
Published in Antimicrobial agents and chemotherapy (01.11.2014)
Published in Antimicrobial agents and chemotherapy (01.11.2014)
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Sofosbuvir in combination with daclatasvir or simeprevir for 12 weeks in noncirrhotic subjects chronically infected with hepatitis C virus genotype 1: a randomized clinical trial
Pott-Junior, H., Bricks, G., Grandi, G., Figueiredo Senise, J., Castelo Filho, A.
Published in Clinical microbiology and infection (01.03.2019)
Published in Clinical microbiology and infection (01.03.2019)
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Cataract Formation in a Child Receiving Dabrafenib and Trametinib Therapy
Botros, Elaine, Bradfield, Yasmin, Pytel, Nicholas
Published in Journal of pediatric ophthalmology and strabismus (01.09.2024)
Published in Journal of pediatric ophthalmology and strabismus (01.09.2024)
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Single-Dose Pharmacokinetics and Safety of Daclatasvir in Subjects with Renal Function Impairment
Garimella, Tushar, Wang, Reena, Luo, Wen-Lin, Hwang, Carey, Sherman, Diane, Kandoussi, Hamza, Marbury, Thomas C, Alcorn, Harry, Bertz, Richard, Bifano, Marc
Published in Antiviral therapy (01.01.2015)
Published in Antiviral therapy (01.01.2015)
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The cost‐effectiveness of testing for NS5a resistance‐associated polymorphisms at baseline in genotype 1a‐infected (treatment‐naïve and treatment‐experienced) subjects treated with all‐oral elbasvir/grazoprevir regimens in the United States
Elbasha, E. H., Robertson, M. N., Nwankwo, C.
Published in Alimentary pharmacology & therapeutics (01.02.2017)
Published in Alimentary pharmacology & therapeutics (01.02.2017)
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The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans
Varnäs, Katarina, Cselényi, Zsolt, Arakawa, Ryosuke, Nag, Sangram, Stepanov, Vladimir, Moein, Mohammad Mahdi, Johnström, Peter, Kingston, Lee, Elmore, Charles S., Halldin, Christer, Farde, Lars
Published in Neuropharmacology (01.01.2020)
Published in Neuropharmacology (01.01.2020)
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A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor
Dennie, Justin, Vandell, Alexander G, Inoue, Satoshi, Gajee, Roohi, Pav, Joseph, Zhang, George, Zamora, Cynthia, Masuda, Nobuhisa, Uchiyama, Minoru, Yamada, Makiko, Senaldi, Giorgio
Published in Journal of clinical pharmacology (01.12.2018)
Published in Journal of clinical pharmacology (01.12.2018)
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