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Sensitivity to imidazoles/nitroimidazoles in subjects sensitized to methylchloroisothiazolinone/methylisothiazolinone: A simple coincidence?
Stingeni, Luca, Rigano, Luigi, Lionetti, Nicola, Bianchi, Leonardo, Tramontana, Marta, Foti, Caterina, Romita, Paolo, Antelmi, Annarita, Bruze, Magnus, Isaksson, Marléne, Hansel, Katharina
Published in Contact dermatitis (01.03.2019)
Published in Contact dermatitis (01.03.2019)
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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration
Muehlan, Clemens, Boehler, Margaux, Brooks, Sander, Zuiker, Rob, van Gerven, Joop, Dingemanse, Jasper
Published in Journal of psychopharmacology (Oxford) (01.03.2020)
Published in Journal of psychopharmacology (Oxford) (01.03.2020)
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Pharmacokinetics and Pharmacodynamics of Tegoprazan Coadministered With Amoxicillin and Clarithromycin in Healthy Subjects
Ghim, Jong-Lyul, Chin, May Chien, Jung, Jinah, Lee, Jiwon, Kim, Seokuee, Kim, Bongtae, Song, Geun Seog, Choi, Young-Kyung, Shin, Jae-Gook
Published in Journal of clinical pharmacology (01.07.2021)
Published in Journal of clinical pharmacology (01.07.2021)
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A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor
Dennie, Justin, Vandell, Alexander G, Inoue, Satoshi, Gajee, Roohi, Pav, Joseph, Zhang, George, Zamora, Cynthia, Masuda, Nobuhisa, Uchiyama, Minoru, Yamada, Makiko, Senaldi, Giorgio
Published in Journal of clinical pharmacology (01.12.2018)
Published in Journal of clinical pharmacology (01.12.2018)
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The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects
Cavallone, Laura F., Montana, Michael C., Frey, Karen, Kallogjeri, Dorina, Wages, James M., Rodebaugh, Thomas L., Doshi, Tina, Kharasch, Evan D., Gereau, Robert W.
Published in Pain (Amsterdam) (01.01.2020)
Published in Pain (Amsterdam) (01.01.2020)
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AZD3293: Pharmacokinetic and Pharmacodynamic Effects in Healthy Subjects and Patients with Alzheimer's Disease
Cebers, Gvido, Alexander, Robert C, Haeberlein, Samantha Budd, Han, David, Goldwater, Ronald, Ereshefsky, Larry, Olsson, Tina, Ye, Naidong, Rosen, Laura, Russell, Muir, Maltby, Justine, Eketjäll, Susanna, Kugler, Alan R
Published in Journal of Alzheimer's disease (01.01.2017)
Published in Journal of Alzheimer's disease (01.01.2017)
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Daridorexant, a new dual orexin receptor antagonist, in elderly subjects with insomnia disorder
Zammit, Gary, Dauvilliers, Yves, Pain, Scott, Sebök Kinter, Dalma, Mansour, Yosef, Kunz, Dieter
Published in Neurology (26.05.2020)
Published in Neurology (26.05.2020)
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A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study
Yazici, Y., McAlindon, T.E., Fleischmann, R., Gibofsky, A., Lane, N.E., Kivitz, A.J., Skrepnik, N., Armas, E., Swearingen, C.J., DiFrancesco, A., Tambiah, J.R.S., Hood, J., Hochberg, M.C.
Published in Osteoarthritis and cartilage (01.10.2017)
Published in Osteoarthritis and cartilage (01.10.2017)
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Safety, Tolerability and Pharmacokinetics of Single Ascending and Multiple Oral Doses of Tegoprazan in Healthy Chinese Subjects
He, Jinjie, Cao, Guoying, Yu, Jicheng, Wang, Jingjing, Cheng, Nengneng, Wu, Jufang, Zhang, Jing, Wu, Xiaojie, Zhang, Basheng, Lu, Jiayan, Chen, Shangzhi
Published in Clinical drug investigation (01.01.2021)
Published in Clinical drug investigation (01.01.2021)
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Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ‐12420), a novel potassium‐competitive acid blocker, in healthy male subjects
Han, Sungpil, Choi, Hee Youn, Kim, Yo Han, Nam, Ji Yeon, Kim, Bongtae, Song, Geun Seog, Lim, Hyeong‐Seok, Bae, Kyun‐Seop
Published in Alimentary pharmacology & therapeutics (01.10.2019)
Published in Alimentary pharmacology & therapeutics (01.10.2019)
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Comparative Intra‐Subject Analysis of Gene Expression and Protein Abundance of Major and Minor Drug Metabolizing Enzymes in Healthy Human Jejunum and Liver
Wenzel, Christoph, Lapczuk‐Romanska, Joanna, Malinowski, Damian, Ostrowski, Marek, Drozdzik, Marek, Oswald, Stefan
Published in Clinical pharmacology and therapeutics (01.02.2024)
Published in Clinical pharmacology and therapeutics (01.02.2024)
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A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis
Friedman, Scott L., Ratziu, Vlad, Harrison, Stephen A., Abdelmalek, Manal F., Aithal, Guruprasad P., Caballeria, Juan, Francque, Sven, Farrell, Geoffrey, Kowdley, Kris V., Craxi, Antonio, Simon, Krzysztof, Fischer, Laurent, Melchor‐Khan, Liza, Vest, Jeffrey, Wiens, Brian L., Vig, Pamela, Seyedkazemi, Star, Goodman, Zachary, Wong, Vincent Wai‐Sun, Loomba, Rohit, Tacke, Frank, Sanyal, Arun, Lefebvre, Eric
Published in Hepatology (Baltimore, Md.) (01.05.2018)
Published in Hepatology (Baltimore, Md.) (01.05.2018)
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The Therapeutic Potential of 2-{[4-(2-methoxyphenyl)piperazin-1-yl]alkyl}-1H-benzo[d]imidazoles as Ligands for Alpha1-Adrenergic Receptor - Comparative In Silico and In Vitro Study
Penjišević, Jelena Z., Šukalović, Vladimir B., Andrić, Deana B., Suručić, Relja, Kostić-Rajačić, Sladjana V.
Published in Applied biochemistry and biotechnology (01.08.2022)
Published in Applied biochemistry and biotechnology (01.08.2022)
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Semi‐Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA
Meng, Amy, Humeniuk, Rita, Jürgensmeier, Juliane M., Hsueh, Chia‐Hsiang, Matzkies, Franziska, Grant, Ethan, Truong, Hoa, Billin, Andrew N., Yu, Helen, Feng, Joy, Kwan, Ellen, Tarnowski, Thomas, Nelson, Cara H.
Published in Clinical pharmacology and therapeutics (01.02.2022)
Published in Clinical pharmacology and therapeutics (01.02.2022)
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Sofosbuvir in combination with daclatasvir or simeprevir for 12 weeks in noncirrhotic subjects chronically infected with hepatitis C virus genotype 1: a randomized clinical trial
Pott-Junior, H., Bricks, G., Grandi, G., Figueiredo Senise, J., Castelo Filho, A.
Published in Clinical microbiology and infection (01.03.2019)
Published in Clinical microbiology and infection (01.03.2019)
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Pharmacokinetics of elbasvir and grazoprevir in subjects with end-stage renal disease or severe renal impairment
Caro, Luzelena, Wenning, Larissa, Feng, Hwa-Ping, Guo, Zifang, Du, Lihong, Bhagunde, Pratik, Fandozzi, Christine, Panebianco, Deborah, Marshall, William L., Butterton, Joan R., Iwamoto, Marian, Yeh, Wendy W.
Published in European journal of clinical pharmacology (01.05.2019)
Published in European journal of clinical pharmacology (01.05.2019)
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Effects of Ketoconazole on the Pharmacokinetics of Ponatinib in Healthy Subjects
Narasimhan, Narayana I., Dorer, David J., Niland, Katie, Haluska, Frank, Sonnichsen, Daryl
Published in Journal of clinical pharmacology (01.09.2013)
Published in Journal of clinical pharmacology (01.09.2013)
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The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study
Schmieder, Roland E, Wagner, Frank, Mayr, Michael, Delles, Christian, Ott, Christian, Keicher, Christian, Hrabak-Paar, Maja, Heye, Tobias, Aichner, Solveig, Khder, Yasser, Yates, Denise, Albrecht, Diego, Langenickel, Thomas, Freyhardt, Patrick, Janka, Rolf, Bremerich, Jens
Published in European heart journal (21.11.2017)
Published in European heart journal (21.11.2017)
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Single-Dose Pharmacokinetics and Safety of Daclatasvir in Subjects with Renal Function Impairment
Garimella, Tushar, Wang, Reena, Luo, Wen-Lin, Hwang, Carey, Sherman, Diane, Kandoussi, Hamza, Marbury, Thomas C, Alcorn, Harry, Bertz, Richard, Bifano, Marc
Published in Antiviral therapy (01.01.2015)
Published in Antiviral therapy (01.01.2015)
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The structure – Activity correlation in the family of dicationic imidazolium surfactants: Antimicrobial properties and cytotoxic effect
Voloshina, Alexandra D., Gumerova, Syumbelya K., Sapunova, Аnastasiia S., Kulik, Natalia V., Mirgorodskaya, Alla B., Kotenko, Alla A., Prokopyeva, Tatiana M., Mikhailov, Vasilii A., Zakharova, Lucia Ya, Sinyashin, Oleg G.
Published in Biochimica et biophysica acta. General subjects (01.12.2020)
Published in Biochimica et biophysica acta. General subjects (01.12.2020)
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