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Pharmacokinetics, Metabolism, and Excretion of [14C]Axitinib, a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Humans
Smith, Bill J., Pithavala, Yazdi, Bu, Hai-Zhi, Kang, Ping, Hee, Brian, Deese, Alan J., Pool, William F., Klamerus, Karen J., Wu, Ellen Y., Dalvie, Deepak K.
Published in Drug metabolism and disposition (01.05.2014)
Published in Drug metabolism and disposition (01.05.2014)
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Enrichment technique to allow early detection and monitor emergence of KRAS mutation in response to treatment
Kitagawa, Yoshiyasu, Okumura, Kazuhiro, Watanabe, Takayoshi, Tsukamoto, Kei, Kitano, Shiro, Nankinzan, Rino, Suzuki, Takuto, Hara, Taro, Soda, Hiroaki, Denda, Tadamichi, Yamaguchi, Taketo, Nagase, Hiroki
Published in Scientific reports (05.08.2019)
Published in Scientific reports (05.08.2019)
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Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution
Nishihara, Ryo, Suzuki, Hideyuki, Hoshino, Emi, Suganuma, Sakura, Sato, Moritoshi, Saitoh, Tsuyoshi, Nishiyama, Shigeru, Iwasawa, Naoko, Citterio, Daniel, Suzuki, Koji
Published in Chemical communications (Cambridge, England) (01.01.2015)
Published in Chemical communications (Cambridge, England) (01.01.2015)
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Circulating progenitor cells in hypertensive subjects: Effectiveness of a treatment with olmesartan in improving cell number and miR profile in addition to expected pharmacological effects
Mandraffino, Giuseppe, Aragona, Caterina Oriana, Cairo, Valentina, Scuruchi, Michele, Lo Gullo, Alberto, D’Ascola, Angela, Alibrandi, Angela, Loddo, Saverio, Quartuccio, Sebastiano, Morace, Carmela, Mormina, Enricomaria, Basile, Giorgio, Saitta, Antonino, Imbalzano, Egidio
Published in PloS one (16.03.2017)
Published in PloS one (16.03.2017)
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Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects
Ménard, Joël, Rigel, Dean F, Watson, Catherine, Jeng, Arco Y, Fu, Fumin, Beil, Michael, Liu, Jing, Chen, Wei, Hu, Chii-Whei, Leung-Chu, Jennifer, LaSala, Daniel, Liang, Guiqing, Rebello, Sam, Zhang, Yiming, Dole, William P
Published in Journal of translational medicine (10.12.2014)
Published in Journal of translational medicine (10.12.2014)
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Diminished reliability of tryptase as risk indicator of mastocytosis in older overweight subjects
Vos, Byrthe J.P.R., van der Veer, Eveline, van Voorst Vader, Pieter C., Mulder, André B., van der Heide, Sicco, Arends, Suzanne, Kluin-Nelemans, Johanna C., de Monchy, Jan G.R., van Doormaal, Jasper J., Oude Elberink, Joanne N.G.
Published in Journal of allergy and clinical immunology (01.03.2015)
Published in Journal of allergy and clinical immunology (01.03.2015)
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Correlation between initial tumour volume and treatment duration on Dabrafenib: observation study of subjects with BRAF mutant melanoma on the BRF112680 trial
Ali, Arwa, Dumbrava, Monica, Riddell, Kylie, Stewart, Nina, Ward, Robyn, Ibrahim, Ahmed K., Chin, Melvin
Published in BMC cancer (22.04.2020)
Published in BMC cancer (22.04.2020)
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Lipid and Corticosteroid Biomarkers Under the Influence of Bisphosphonates
Tou, Kathy, Cawley, Adam, Noble, Glenys, Loy, Jaymie, Bishop, David, Keledjian, John, Sornalingam, Kireesan, Richards, Stacey, Fu, Shanlin
Published in Drug testing and analysis (01.07.2025)
Published in Drug testing and analysis (01.07.2025)
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Daridorexant, a New Dual Orexin Receptor Antagonist to Treat Insomnia Disorder
Dauvilliers, Yves, Zammit, Gary, Fietze, Ingo, Mayleben, David, Seboek Kinter, Dalma, Pain, Scott, Hedner, Jan
Published in Annals of neurology (01.03.2020)
Published in Annals of neurology (01.03.2020)
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Pharmacokinetics and Tolerability of Etamicastat Following Single and Repeated Administration in Elderly Versus Young Healthy Male Subjects: An Open-Label, Single-Center, Parallel-Group Study
Nunes, Teresa, Rocha, José Francisco, Vaz-da-Silva, Manuel, Falcão, Amilcar, Almeida, Luis, Soares-da-Silva, Patricio
Published in Clinical therapeutics (01.06.2011)
Published in Clinical therapeutics (01.06.2011)
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Drug interaction evaluation of the novel phosphodiesterase type 5 inhibitor tunodafil (youkenafil): Effects of tunodafil on omeprazole pharmacokinetics based on CYP2C19 gene polymorphism, and effects of ritonavir on tunodafil pharmacokinetics
Wang, Keli, Ding, Juefang, Cheng, Minlu, Li, Xianjing, Zhou, Huan, Song, Qinxin, Yang, Yuanxun, Li, Juan, Ding, Li
Published in European journal of pharmaceutical sciences (01.03.2025)
Published in European journal of pharmaceutical sciences (01.03.2025)
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Efficacy and safety of daclatasvir plus pegylated-interferon alfa 2a and ribavirin in previously untreated HCV subjects coinfected with HIV and HCV genotype-1: a Phase III, open-label study
Sulkowski, Mark S., Fessel, Walford J., Lazzarin, Adriano, Berenguer, Juan, Zakharova, Natalia, Cheinquer, Hugo, Côté, Pierre, Dieterich, Douglas, Gadano, Adrian, Matthews, Gail, Molina, Jean-Michel, Moreno, Christophe, Pineda, Juan Antonio, Pulido, Federico, Rivero, Antonio, Rockstroh, Jurgen, Hernandez, Dennis, McPhee, Fiona, Eley, Timothy, Liu, Zhaohui, Mendez, Patricia, Hughes, Eric, Noviello, Stephanie, Ackerman, Peter
Published in Hepatology international (01.03.2017)
Published in Hepatology international (01.03.2017)
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The impact of sofosbuvir/daclatasvir or ribavirin in patients with severe COVID-19
Eslami, Gholamali, Mousaviasl, Sajedeh, Radmanesh, Esmat, Jelvay, Saeed, Bitaraf, Saeid, Simmons, Bryony, Wentzel, Hannah, Hill, Andrew, Sadeghi, Anahita, Freeman, James, Salmanzadeh, Shokrollah, Esmaeilian, Hani, Mobarak, Morteza, Tabibi, Ramin, Jafari Kashi, Amir Hosein, Lotfi, Zahra, Talebzadeh, Seyed Mehdi, Wickramatillake, Aseni, Momtazan, Mahboobeh, Hajizadeh Farsani, Majid, Marjani, Sedigheh, Mobarak, Sara
Published in Journal of antimicrobial chemotherapy (01.11.2020)
Published in Journal of antimicrobial chemotherapy (01.11.2020)
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Safety of long-term denosumab therapy: results from the open label extension phase of two phase 3 studies in patients with metastatic breast and prostate cancer
Stopeck, Alison T., Fizazi, Karim, Body, Jean-Jacques, Brown, Janet E., Carducci, Michael, Diel, Ingo, Fujiwara, Yasuhiro, Martín, Miguel, Paterson, Alexander, Tonkin, Katia, Shore, Neal, Sieber, Paul, Kueppers, Frank, Karsh, Lawrence, Yardley, Denise, Wang, Huei, Maniar, Tapan, Arellano, Jorge, Braun, Ada
Published in Supportive care in cancer (01.01.2016)
Published in Supportive care in cancer (01.01.2016)
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Kinetics of imidazole propionate from orally delivered histidine in mice and humans
Warmbrunn, Moritz V., Attaye, Ilias, Horak, Anthony, Banerjee, Rakhee, Massey, William J., Varadharajan, Venkateshwari, Rampanelli, Elena, Hao, Youling, Dutta, Sumita, Nemet, Ina, Aron-Wisnewsky, Judith, Clément, Karine, Koopen, Annefleur, Wortelboer, Koen, Bergh, Per-Olof, Davids, Mark, Mohamed, Nadia, Kemper, E. Marleen, Hazen, Stanley, Groen, Albert K., van Raalte, Daniel H., Herrema, Hilde, Backhed, Fredrik, Brown, J. Mark, Nieuwdorp, Max
Published in NPJ biofilms and microbiomes (04.11.2024)
Published in NPJ biofilms and microbiomes (04.11.2024)
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Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator
Muehlan, Clemens, Brooks, Sander, Vaillant, Cedric, Meinel, Michael, Jacobs, Gabriël E., Zuiker, Rob G., Dingemanse, Jasper
Published in Clinical pharmacology and therapeutics (01.06.2022)
Published in Clinical pharmacology and therapeutics (01.06.2022)
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Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C
Kato, Keizo, Shimada, Noritomo, Atsukawa, Masanori, Abe, Hiroshi, Itokawa, Norio, Matsumoto, Yoshihiro, Agata, Rie, Tsubota, Akihito
Published in PloS one (10.07.2019)
Published in PloS one (10.07.2019)
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