Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort
Meertens, Marinda, Giraud, Eline L., van der Kleij, Maud B. A., Westerdijk, Kim, Guchelaar, Niels A. D., Bleckman, Roos F., Rieborn, Amy, Imholz, Alex L. T, Otten, Hans-Martin, Vulink, Annelie, Los, Maartje, Hamberg, Paul, van der Graaf, Winette T. A., Gelderblom, Hans, Moes, Dirk Jan A. R., Broekman, K. Esther, Touw, Daan J., Koolen, Stijn L. W., Mathijssen, Ron H. J., Huitema, Alwin D. R., van Erp, Nielka P., Desar, Ingrid M. E., Steeghs, Neeltje
Published in Clinical pharmacokinetics (01.07.2024)
Published in Clinical pharmacokinetics (01.07.2024)
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Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
de Groot, Stefanie, Lugtenberg, Rieneke T., Cohen, Danielle, Welters, Marij J. P., Ehsan, Ilina, Vreeswijk, Maaike P. G., Smit, Vincent T. H. B. M., de Graaf, Hiltje, Heijns, Joan B., Portielje, Johanneke E. A., van de Wouw, Agnes J., Imholz, Alex L. T., Kessels, Lonneke W., Vrijaldenhoven, Suzan, Baars, Arnold, Kranenbarg, Elma Meershoek-Klein, Carpentier, Marjolijn Duijm-de, Putter, Hein, van der Hoeven, Jacobus J. M., Nortier, Johan W. R., Longo, Valter D., Pijl, Hanno, Kroep, Judith R.
Published in Nature communications (23.06.2020)
Published in Nature communications (23.06.2020)
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High-dose alkylating chemotherapy in BRCA-altered triple-negative breast cancer: the randomized phase III NeoTN trial
Vliek, Sonja, Hilbers, Florentine S., van Werkhoven, Erik, Mandjes, Ingrid, Kessels, Rob, Kleiterp, Sieta, Lips, Esther H., Mulder, Lennart, Kayembe, Mutamba T., Loo, Claudette E., Russell, Nicola S., Vrancken Peeters, Marie-Jeanne T. F. D., Holtkamp, Marjo J., Schot, Margaret, Baars, Joke W., Honkoop, Aafke H., Vulink, Annelie J. E., Imholz, Alex L. T., Vrijaldenhoven, Suzan, van den Berkmortel, Franchette W. P. J., Meerum Terwogt, Jetske M., Schrama, Jolanda G., Kuijer, Philomeen, Kroep, Judith R., van der Padt-Pruijsten, Annemieke, Wesseling, Jelle, Sonke, Gabe S., Gilhuijs, Kenneth G. A., Jager, Agnes, Nederlof, Petra, Linn, Sabine C.
Published in NPJ breast cancer (09.09.2023)
Published in NPJ breast cancer (09.09.2023)
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Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness
Lips, Esther H, Laddach, Nadja, Savola, Suvi P, Vollebergh, Marieke A, Oonk, Anne M M, Imholz, Alex L T, Wessels, Lodewyk F A, Wesseling, Jelle, Nederlof, Petra M, Rodenhuis, Sjoerd
Published in Breast cancer research : BCR (27.10.2011)
Published in Breast cancer research : BCR (27.10.2011)
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Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013–14) trial
Lugtenberg, Rieneke T., de Groot, Stefanie, Kaptein, Ad A., Fischer, Maarten J., Kranenbarg, Elma Meershoek-Klein, Carpentier, Marjolijn Duijm-de, Cohen, Danielle, de Graaf, Hiltje, Heijns, Joan B., Portielje, Johanneke E. A., van de Wouw, Agnes J., Imholz, Alex L. T., Kessels, Lonneke W., Vrijaldenhoven, Suzan, Baars, Arnold, Fiocco, Marta, van der Hoeven, Jacobus J. M., Gelderblom, Hans, Longo, Valter D., Pijl, Hanno, Kroep, Judith R.
Published in Breast cancer research and treatment (01.02.2021)
Published in Breast cancer research and treatment (01.02.2021)
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Journal Article
Tyrosine Kinase Inhibitors and Proton Pump Inhibitors: An Evaluation of Treatment Options
van Leeuwen, Roelof W. F., Jansman, Frank G. A., Hunfeld, Nicole G., Peric, Robert, Reyners, Anna K. L., Imholz, Alex L. T., Brouwers, Jacobus R. B. J., Aerts, Joachim G., van Gelder, Teun, Mathijssen, Ron H. J.
Published in Clinical pharmacokinetics (01.07.2017)
Published in Clinical pharmacokinetics (01.07.2017)
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Journal Article
Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology – an analysis of the closed cohorts of a multicentre prospective study
van der Kleij, Maud B. A., Guchelaar, Niels A. D., Meertens, Marinda, Westerdijk, Kim, Giraud, Eline L., Bleckman, Roos F., Groenland, Stefanie L., van Eerden, Ruben A. G., Imholz, Alex L. T., Vulink, Annelie J. E., Otten, Hans-Martin, Fiebrich-Westra, Helle-Brit, Lubberman, Floor J. E., Desar, Ingrid M. E., Moes, Dirk-Jan A. R., Touw, Daan J., Koolen, Stijn L. W., Gelderblom, Hans, Reyners, An K. L., van Erp, Nielka P., Mathijssen, Ron H. J., Huitema, Alwin D. R., Steeghs, Neeltje
Published in British journal of cancer (01.09.2024)
Published in British journal of cancer (01.09.2024)
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Digital image analysis of HER2 immunohistochemistry in gastric‐ and oesophageal adenocarcinoma: a validation study on biopsies and surgical specimens
Koopman, Timco, Bock, Geertruida H, Buikema, Henk J, Smits, Maria M, Louwen, Maarten, Hage, Mariska, Imholz, Alex L T, Vegt, Bert
Published in Histopathology (01.01.2018)
Published in Histopathology (01.01.2018)
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A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy‐free approach in HER2‐positive metastatic breast cancer: The HAT study (BOOG 2008‐2003), a Dutch Breast Cancer Research Group trial
Drooger, Jan C., van Tinteren, Harm, de Groot, Steffen M., ten Tije, Albert J., de Graaf, Hiltje, Portielje, Johanneke E. A., Jager, Agnes, Honkoop, Aafke, Linn, Sabine C., Kroep, Judith R., Erdkamp, Frans L. G., Hamberg, Paul, Imholz, Alex L. T., van Rossum‐Schornagel, Quirine C., Heijns, Joan B., van Leeuwen‐Stok, A. Elise, Sleijfer, Stefan
Published in Cancer (01.10.2016)
Published in Cancer (01.10.2016)
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Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study
With, Mirjam, Knikman, Jonathan, Man, Femke M., Lunenburg, Carin A. T. C., Henricks, Linda M., Kuilenburg, André B. P., Maring, Jan G., Staveren, Maurice C., Vries, Niels, Rosing, Hilde, Beijnen, Jos H., Pluim, Dick, Modak, Anil, Imholz, Alex L. T., Schaik, Ron H. N., Schellens, Jan H. M., Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk‐Jan, Mathijssen, Ron H. J., Swen, Jesse J., Meulendijks, Didier
Published in Clinical pharmacology and therapeutics (01.07.2022)
Published in Clinical pharmacology and therapeutics (01.07.2022)
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70-Gene signature-guided adjuvant systemic treatment adjustments in early-stage ER+ breast cancer patients: 7-year follow-up of a prospective multicenter cohort study
Verreck, Eline E F, Kuijer, Anne, van Steenhoven, Julia E C, Volders, José H, van der Velden, Annette W G, Siesling, Sabine, Timmer-Bonte, Anja N H, Smilde, Tineke J, Imholz, Alex L T, Blanken-Peeters, Charlotte F J M, de Valk, Bart, Vrijaldenhoven, Suzan, Lastdrager, Willem B, Haringhuizen, Annebeth W, Hunting, Jarmo C B, Hovenga, Sjoerd, Nieboer, Peter, Zuetenhorst, Hanneke M, Tetteroo, Geert W M, Smorenburg, Carolien H, van Maaren, Marissa C, van Dalen, Thijs
Published in Breast cancer research and treatment (30.09.2024)
Published in Breast cancer research and treatment (30.09.2024)
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Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments
Kester, Lennart, Seinstra, Danielle, van Rossum, Annelot G J, Vennin, Claire, Hoogstraat, Marlous, van der Velden, Daphne, Opdam, Mark, van Werkhoven, Erik, Hahn, Kerstin, Nederlof, Iris, Lips, Ester H, Mandjes, Ingrid A M, van Leeuwen-Stok, A Elise, Canisius, Sander, van Tinteren, Harm, Imholz, Alex L T, Portielje, Johanneke E A, Bos, Monique E M M, Bakker, Sandra D, Rutgers, Emiel J, Horlings, Hugo M, Wesseling, Jelle, Voest, Emile E, Wessels, Lodewyk F A, Kok, Marleen, Oosterkamp, Hendrika M, van Oudenaarden, Alexander, Linn, Sabine C, van Rheenen, Jacco
Published in Clinical cancer research (01.03.2022)
Published in Clinical cancer research (01.03.2022)
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Journal Article
Pathologic Diagnostics of HER2 Positivity in Gastroesophageal Adenocarcinoma
Koopman, Timco, Louwen, Maarten, Hage, Mariska, Smits, Maria M., Imholz, Alex L.T.
Published in American journal of clinical pathology (01.02.2015)
Published in American journal of clinical pathology (01.02.2015)
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Prevalence and follow-up of potentially inappropriate medication and potentially omitted medication in older patients with cancer – The PIM POM study
van Loveren, Fianne M.A.M., van Berlo - van de Laar, Inge R.F., Imholz, Alex L.T., van ’t Riet, Esther, Taxis, Katja, Jansman, Frank G.A.
Published in Journal of geriatric oncology (01.01.2021)
Published in Journal of geriatric oncology (01.01.2021)
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Independent replication of polymorphisms predicting toxicity in breast cancer patients randomized between dose-dense and docetaxel-containing adjuvant chemotherapy
van Rossum, Annelot G J, Kok, Marleen, McCool, Danielle, Opdam, Mark, Miltenburg, Nienke C, Mandjes, Ingrid A M, van Leeuwen-Stok, Elise, Imholz, Alex L T, Portielje, Johanneke E A, Bos, Monique M E M, van Bochove, Aart, van Werkhoven, Erik, Schmidt, Marjanka K, Oosterkamp, Hendrika M, Linn, Sabine C
Published in Oncotarget (26.12.2017)
Published in Oncotarget (26.12.2017)
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Journal Article
Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial
Opdam, Mark, van Rossum, Annelot G.J., Hoogstraat, Marlous, Bounova, Gergana, Horlings, Hugo M., van Werkhoven, Erik, Mandjes, Ingrid A.M., van Leeuwen – Stok, A. Elise, Canisius, Sander, van Tinteren, Harm, Imholz, Alex L.T., Portielje, Johanneke E.A., Bos, Monique E.M.M., Bakker, Sandra, Wesseling, Jelle, Kester, Lennart, van Rheenen, Jacco, Rutgers, Emiel J., de Menezes, Renee X., Wessels, Lodewyk F.A., Kok, Marleen, Oosterkamp, Hendrika M., Linn, Sabine C., Linn, Sabine C., Soesan, Marcel, Oosterkamp, Rianne M., Jeurissen, Frank, Weijl, Nir, Imholz, Alex L.T., Portielje, Johanneke E.A., Beelen, Karin J., Bos, Monique E.M.M., van Bochove, Aart, de Klerk, Gerty, Vrijaldenhoven, Suzan, van der Velden, Annette, de Graaf, Hiltje, Smeets, Marielle, Terwogt, Jetske Meerum, Schrama, Jolanda, Kuijer, Philomeen, Wilmink, Hanneke, Hoekstra, Ronald, Kroep, Judith, Pruijt, Hans F.M., van Gerven, Leander, Vos, Allert H., Erdkamp, Frans, van Leeuwen-Breuk, Willemien G., de Graeff, Alexander
Published in iScience (16.08.2024)
Published in iScience (16.08.2024)
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