Oncogenic RAS promotes leukemic transformation of CUX1-deficient cells
An, Ningfei, Khan, Saira, Imgruet, Molly K., Jueng, Lia, Gurbuxani, Sandeep, McNerney, Megan E.
Published in Oncogene (16.03.2023)
Published in Oncogene (16.03.2023)
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Journal Article
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS
An, Ningfei, Khan, Saira, Imgruet, Molly K., Gurbuxani, Sandeep K., Konecki, Stephanie N., Burgess, Michael R., McNerney, Megan E.
Published in Blood (14.06.2018)
Published in Blood (14.06.2018)
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Journal Article
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms
Imgruet, Molly K., Lutze, Julian, An, Ningfei, Hu, Bonnie, Khan, Saira, Kurkewich, Jeffrey, Martinez, Tanner C., Wolfgeher, Donald, Gurbuxani, Sandeep K., Kron, Stephen J., McNerney, Megan E.
Published in Blood (02.09.2021)
Published in Blood (02.09.2021)
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Journal Article
CUX1 Deficiency Potentiates RAS Signaling to Drive Malignancy
An, Ningfei, Imgruet, Molly K, Khan, Saira, Jueng, Lia, Gurbuxani, Sandeep, McNerney, Megan E.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Combined Deficiency of Chromosome 7 Myeloid Tumor Suppressors Enhances Chemotherapy Resistance
Jotte, Matthew R. M., Martinez, Tanner C., Stoddart, Angela, Imgruet, Molly K., Nam, Henna S., Hu, Bonnie, Khan, Saira, An, Ningfei, McNerney, Megan E.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
3009 – COMBINED DEFICIENCY OF CHROMOSOME 7 MYELOID TUMOR SUPPRESSORS ENHANCES CHEMOTHERAPY RESISTANCE
Jotte, Matthew, Martinez, Tanner, Stoddart, Angela, Imgruet, Molly, Nam, Henna, Hu, Bonnie, Khan, Saira, An, Ningfei, McNerney, Megan
Published in Experimental hematology (2023)
Published in Experimental hematology (2023)
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Journal Article
Deficiency of CUX1, Encoded on 7q, Blocks the Normal HSC DNA Damage Response and Drives Highly Penetrant Therapy-Related Myeloid Neoplasms in Mice
Imgruet, Molly K, An, Ningfei, Khan, Saira, Lutze, Julian K, Hu, Bonnie, Kron, Stephen J., Gurbuxani, Sandeep, McNerney, Megan E.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
3111 – LOSS OF A 7Q GENE, CUX1, DISRUPTS EPIGENETIC-DRIVEN DNA REPAIR AND CAUSES THERAPY-RELATED MYELOID NEOPLASM
McNerney, Megan, Imgruet, Molly, Lutze, Julian, Hu, Bonnie, Khan, Saira, Kurkewich, Jeffrey, Wolfgeher, Don, An, Ningfei, Gurbuxani, Sandeep, Kron, Steve
Published in Experimental hematology (01.08.2020)
Published in Experimental hematology (01.08.2020)
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Journal Article
Deficiency of Cux1, Encoded on Human Chromosome 7q, Causes Aberrant Hematopoietic Stem Cell Function and Spontaneous Myeloproliferative Disease in Mice
An, Ningfei, Khan, Saira, Imgruet, Molly, Gurbuxani, Sandeep, Burgess, Michael R., McNerney, Megan E.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen
Ghodke-Puranik, Yogita, Imgruet, Molly, Dorschner, Jessica M., Shrestha, Prakriti, McCoy, Kaci, Kelly, Jennifer A., Marion, Miranda, Guthridge, Joel M., Langefeld, Carl D., Harley, John B., James, Judith A., Sivils, Kathy L., Niewold, Timothy B.
Published in Cytokine (Philadelphia, Pa.) (01.08.2020)
Published in Cytokine (Philadelphia, Pa.) (01.08.2020)
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Journal Article