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Pharmacology of β-l-Thymidine and β-l-2′-Deoxycytidine in HepG2 Cells and Primary Human Hepatocytes: Relevance to Chemotherapeutic Efficacy against Hepatitis B Virus
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Mononucleoside Phosphotriester Derivatives with S-Acyl-2-thioethyl Bioreversible Phosphate-Protecting Groups: Intracellular Delivery of 3'-Azido-2',3'-dideoxythymidine 5'-Monophosphate
Lefebvre, Isabelle, Perigaud, Christian, Pompon, Alain, Aubertin, Anne-Marie, Girardet, Jean-Luc, Kirn, Andre, Gosselin, Gilles, Imbach, Jean-Louis
Published in Journal of medicinal chemistry (01.09.1995)
Published in Journal of medicinal chemistry (01.09.1995)
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Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro
GOSSELIN, G, SCHINAZI, R. F, SOMMADOSSI, J.-P, MATHE, C, BERGOGNE, M.-C, AUBERTIN, A.-M, KIRN, A, IMBACH, J.-L
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SATE pronucleotide approaches: an overview
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New bis(SATE) prodrug of AZT 5′‐monophosphate: In vitro anti‐HIV activity, stability, and potential oral absorption
Shafiee, M., Deferme, S., Villard, A.‐L., Egron, D., Gosselin, G., Imbach, J.‐L., Lioux, T., Pompon, A., Varray, S., Aubertin, A.‐M., Mooter, G.Van Den, Kinget, R., Périgaud, C., Augustijns, P.
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Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro
SCHINAZI, R. F, GOSSELIN, G, ABDESSLEM FARAJ, KORBA, B. E, LIOTTA, D. C, CHU, C. K, MATHE, C, IMBACH, J.-L, SOMMADOSSI, J.-P
Published in Antimicrobial Agents and Chemotherapy (01.09.1994)
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Decomposition Pathways and in Vitro HIV Inhibitory Effects of IsoddA Pronucleotides: Toward a Rational Approach for Intracellular Delivery of Nucleoside 5‘-Monophosphates
Valette, Gilles, Pompon, Alain, Girardet, Jean-Luc, Cappellacci, Loredana, Franchetti, Palmarisa, Grifantini, Mario, La Colla, Paolo, Loi, Anna Giulia, Périgaud, Christian, Gosselin, Gilles, Imbach, Jean-Louis
Published in Journal of medicinal chemistry (10.05.1996)
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Comparative analysis of anti-human immunodeficiency virus type 1 activities of dideoxynucleoside analogs in resting and activated peripheral blood mononuclear cells
SHIRASAKA, T, CHOKEKIJCHAI, S, YAMADA, A, GOSSELIN, G, IMBACH, J.-L, MITSUYA, H
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Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides
Guerlavais, T, Meyer, A, Debart, F, Imbach, J-L, Morvan, F, Vasseur, J-J
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Synthesis of ( Z) and ( E) α-alkenyl phosphonic acid derivatives of purines and pyrimidines
Lazrek, H.B., Rochdi, A., Khaider, H., Barascut, J.-L., Imbach, J.-L., Balzarini, J., Witvrouw, M., Pannecouque, C., De Clercq, E.
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Effects of nucleotide analogues on human immunodeficiency virus type 1 integrase
Mazumder, A, Neamati, N, Sommadossi, J P, Gosselin, G, Schinazi, R F, Imbach, J L, Pommier, Y
Published in Molecular pharmacology (01.04.1996)
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Published in Molecular pharmacology (01.04.1996)
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Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs
FARAJ, A, AGROFOGLIO, L. A, WAKEFIELD, J. K, MCPHERSON, S, MORROW, C. D, GOSSELIN, G, MATHE, C, IMBACH, J.-L, SCHINAZI, R. F, SOMMADOSSI, J.-P
Published in Antimicrobial Agents and Chemotherapy (01.10.1994)
Published in Antimicrobial Agents and Chemotherapy (01.10.1994)
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The pro-oligonucleotide approach: Solid phase synthesis and preliminary evaluation of model pro-dodecathymidylates
Tosquellas, Guilhem, Alvarez, Karine, Dell'Aquila, Christelle, Morvan, François, Vasseur, Jean-Jacques, Imbach, Jean-Louis, Rayner, Bernard
Published in Nucleic acids research (01.05.1998)
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S-acyl-2-thioethyl (SATE) pronucleotides are potent inhibitors of HIV-1 replication in T-lymphoid cells cross-resistant to deoxycytidine and thymidine analogs
Gröschel, B, Cinatl, J, Périgaud, C, Gosselin, G, Imbach, J.-L, Doerr, H.W, Cinatl, J
Published in Antiviral research (01.02.2002)
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Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA BIS(SATE)phosphotriester and 3′-azido-2′,3′-dideoxythymidine
Pericaud, Christian, Aubertin, Anne-Marie, Benzaria, Samira, Pelicano, Helene, Girardet, Jean-Luc, Maury, Georges, Gosselin, Gilles, Kirn, Andre, Imbach, Jean-Louis
Published in Biochemical pharmacology (05.07.1994)
Published in Biochemical pharmacology (05.07.1994)
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Mutagenicity of a unique apurinic/apyrimidinic site in mammalian cells
Gentil, A., Cabral-Neto, J.B., Mariage-Samson, R., Margot, A., Imbach, J.L., Rayner, B., Sarasin, A.
Published in Journal of molecular biology (20.10.1992)
Published in Journal of molecular biology (20.10.1992)
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