Structural and functional alterations in different types of delusions across schizophrenia spectrum: A systematic review
Dudina, Anastasiia N., Tomyshev, Alexander S., Ilina, Ekaterina V., Romanov, Dmitriy V., Lebedeva, Irina S.
Published in Progress in neuro-psychopharmacology & biological psychiatry (10.01.2025)
Published in Progress in neuro-psychopharmacology & biological psychiatry (10.01.2025)
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New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors
Filimonov, Aleksander S, Chepanova, Arina A, Luzina, Olga A, Zakharenko, Alexandra L, Zakharova, Olga D, Ilina, Ekaterina S, Dyrkheeva, Nadezhda S, Kuprushkin, Maxim S, Kolotaev, Anton V, Khachatryan, Derenik S, Patel, Jinal, Leung, Ivanhoe K H, Chand, Raina, Ayine-Tora, Daniel M, Reynisson, Johannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (15.10.2019)
Published in Molecules (Basel, Switzerland) (15.10.2019)
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Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1
Il'ina, Irina V, Dyrkheeva, Nadezhda S, Zakharenko, Alexandra L, Sidorenko, Alexander Yu, Li-Zhulanov, Nikolay S, Korchagina, Dina V, Chand, Raina, Ayine-Tora, Daniel M, Chepanova, Arina A, Zakharova, Olga D, Ilina, Ekaterina S, Reynisson, Jóhannes, Malakhova, Anastasia A, Medvedev, Sergey P, Zakian, Suren M, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (31.07.2020)
Published in Molecules (Basel, Switzerland) (31.07.2020)
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Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy
Khomenko, Tatyana M, Zakharenko, Alexandra L, Chepanova, Arina A, Ilina, Ekaterina S, Zakharova, Olga D, Kaledin, Vasily I, Nikolin, Valeriy P, Popova, Nelly A, Korchagina, Dina V, Reynisson, Jóhannes, Chand, Raina, Ayine-Tora, Daniel M, Patel, Jinal, Leung, Ivanhoe K H, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (23.12.2019)
Published in International journal of molecular sciences (23.12.2019)
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The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo
Chernyshova, Irina A, Zakharenko, Aleksandra L, Kurochkin, Nikolay N, Dyrkheeva, Nadezhda S, Kornienko, Tatyana E, Popova, Nelly A, Nikolin, Valeriy P, Ilina, Ekaterina S, Zharkov, Timofey D, Kupryushkin, Maxim S, Oslovsky, Vladimir E, Drenichev, Mikhail S, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (31.12.2022)
Published in Molecules (Basel, Switzerland) (31.12.2022)
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Journal Article
Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments
Munkuev, Aldar A., Mozhaitsev, Evgenii S., Chepanova, Arina A., Suslov, Evgeniy V., Korchagina, Dina V., Zakharova, Olga D., Ilina, Ekaterina S., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Molecules (Basel, Switzerland) (24.05.2021)
Published in Molecules (Basel, Switzerland) (24.05.2021)
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Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors
Gladkova, Elizaveta D, Chepanova, Arina A, Ilina, Ekaterina S, Zakharenko, Alexandra L, Reynisson, Jóhannes, Luzina, Olga A, Volcho, Konstantin P, Lavrik, Olga I, Salakhutdinov, Nariman F
Published in Molecules (Basel, Switzerland) (30.03.2021)
Published in Molecules (Basel, Switzerland) (30.03.2021)
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New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2
Salomatina, Oksana V, Dyrkheeva, Nadezhda S, Popadyuk, Irina I, Zakharenko, Alexandra L, Ilina, Ekaterina S, Komarova, Nina I, Reynisson, Jóhannes, Salakhutdinov, Nariman F, Lavrik, Olga I, Volcho, Konstantin P
Published in Molecules (Basel, Switzerland) (23.12.2021)
Published in Molecules (Basel, Switzerland) (23.12.2021)
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New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1
Dyrkheeva, Nadezhda S, Filimonov, Aleksandr S, Luzina, Olga A, Orlova, Kristina A, Chernyshova, Irina A, Kornienko, Tatyana E, Malakhova, Anastasia A, Medvedev, Sergey P, Zakharenko, Alexandra L, Ilina, Ekaterina S, Anarbaev, Rashid O, Naumenko, Konstantin N, Klabenkova, Kristina V, Burakova, Ekaterina A, Stetsenko, Dmitry A, Zakian, Suren M, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (20.10.2021)
Published in International journal of molecular sciences (20.10.2021)
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Monoterpene substituted thiazolidin-4-ones as novel TDP1 inhibitors: Synthesis, biological evaluation and docking
Ivankin, Dmitry I., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Ilina, Ekaterina S., Zarkov, Timofey O., Reynisson, Jóhannes, Luzina, Olga A., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Bioorganic & medicinal chemistry letters (01.10.2022)
Published in Bioorganic & medicinal chemistry letters (01.10.2022)
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Interaction of PARP-2 with AP site containing DNA
Kutuzov, Mikhail M., Khodyreva, Svetlana N., Ilina, Ekaterina S., Sukhanova, Maria V., Amé, Jean-Christophe, Lavrik, Olga I.
Published in Biochimie (01.05.2015)
Published in Biochimie (01.05.2015)
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Interaction of PARP-2 with DNA structures mimicking DNA repair intermediates and consequences on activity of base excision repair proteins
Kutuzov, Mikhail M., Khodyreva, Svetlana N., Amé, Jean-Christophe, Ilina, Ekaterina S., Sukhanova, Maria V., Schreiber, Valérie, Lavrik, Olga I.
Published in Biochimie (01.06.2013)
Published in Biochimie (01.06.2013)
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Inhibition of Tyrosyl-DNA Phosphodiesterase 1 by Lipophilic Pyrimidine Nucleosides
Zakharenko, Alexandra L, Drenichev, Mikhail S, Dyrkheeva, Nadezhda S, Ivanov, Georgy A, Oslovsky, Vladimir E, Ilina, Ekaterina S, Chernyshova, Irina A, Lavrik, Olga I, Mikhailov, Sergey N
Published in Molecules (Basel, Switzerland) (13.08.2020)
Published in Molecules (Basel, Switzerland) (13.08.2020)
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The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme
Gladkova, Elizaveta D, Nechepurenko, Ivan V, Bredikhin, Roman A, Chepanova, Arina A, Zakharenko, Alexandra L, Luzina, Olga A, Ilina, Ekaterina S, Dyrkheeva, Nadezhda S, Mamontova, Evgeniya M, Anarbaev, Rashid O, Reynisson, Jóhannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan
Munkuev, Aldar A, Dyrkheeva, Nadezhda S, Kornienko, Tatyana E, Ilina, Ekaterina S, Ivankin, Dmitry I, Suslov, Evgeniy V, Korchagina, Dina V, Gatilov, Yuriy V, Zakharenko, Alexandra L, Malakhova, Anastasia A, Reynisson, Jóhannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (24.05.2022)
Published in Molecules (Basel, Switzerland) (24.05.2022)
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New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition
Dyrkheeva, Nadezhda S., Filimonov, Aleksandr S., Luzina, Olga A., Zakharenko, Alexandra L., Ilina, Ekaterina S., Malakhova, Anastasia A., Medvedev, Sergey P., Reynisson, Jóhannes, Volcho, Konstantin P., Zakian, Suren M., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Biomolecules (Basel, Switzerland) (01.07.2021)
Published in Biomolecules (Basel, Switzerland) (01.07.2021)
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Poly(ADP-ribosyl)ation and DNA repair synthesis in the extracts of naked mole rat, mouse, and human cells
Kosova, Anastasiya A, Kutuzov, Mikhail M, Evdokimov, Alexei N, Ilina, Ekaterina S, Belousova, Ekaterina A, Romanenko, Svetlana A, Trifonov, Vladimir A, Khodyreva, Svetlana N, Lavrik, Olga I
Published in Aging (Albany, NY.) (13.05.2019)
Published in Aging (Albany, NY.) (13.05.2019)
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Synthesis of adamantane-monoterpene conjugates with 1,3,4-thiadiazol-2(3H)-imine linker and evaluation of their inhibitory activity against TDP1
Munkuev, Aldar A., Zakharenko, Alexandra L., Kornienko, Tatyana E., Dyrkheeva, Nadezhda S., Ilina, Ekaterina S., Suslov, Evgeniy V., Issa, Fatima, Achara, Chigozie, Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Medicinal chemistry research (01.02.2024)
Published in Medicinal chemistry research (01.02.2024)
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