Advances in HER2-Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer
Meric-Bernstam, Funda, Johnson, Amber M, Dumbrava, Ecaterina E Ileana, Raghav, Kanwal, Balaji, Kavitha, Bhatt, Michelle, Murthy, Rashmi K, Rodon, Jordi, Piha-Paul, Sarina A
Published in Clinical cancer research (01.04.2019)
Published in Clinical cancer research (01.04.2019)
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Journal Article
Precision Oncology Decision Support: Current Approaches and Strategies for the Future
Kurnit, Katherine C, Dumbrava, Ecaterina E Ileana, Litzenburger, Beate, Khotskaya, Yekaterina B, Johnson, Amber M, Yap, Timothy A, Rodon, Jordi, Zeng, Jia, Shufean, Md Abu, Bailey, Ann M, Sánchez, Nora S, Holla, Vijaykumar, Mendelsohn, John, Shaw, Kenna Mills, Bernstam, Elmer V, Mills, Gordon B, Meric-Bernstam, Funda
Published in Clinical cancer research (15.06.2018)
Published in Clinical cancer research (15.06.2018)
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Journal Article
Phase 2 study of pembrolizumab in patients with advanced rare cancers
Naing, Aung, Meric-Bernstam, Funda, Stephen, Bettzy, Karp, Daniel D, Hajjar, Joud, Rodon Ahnert, Jordi, Piha-Paul, Sarina A, Colen, Rivka R, Jimenez, Camilo, Raghav, Kanwal P, Ferrarotto, Renata, Tu, Shi-Ming, Campbell, Matthew, Wang, Linghua, Sabir, Sarjeel H, Tapia, Coya, Bernatchez, Chantale, Frumovitz, Michael, Tannir, Nizar, Ravi, Vinod, Khan, Saria, Painter, Jeane M, Abonofal, Abulrahman, Gong, Jing, Alshawa, Anas, McQuinn, Lacey M, Xu, Mingxuan, Ahmed, Sara, Subbiah, Vivek, Hong, David S, Pant, Shubham, Yap, Timothy A, Tsimberidou, Apostolia M, Dumbrava, Ecaterina E Ileana, Janku, Filip, Fu, Siqing, Simon, Richard M, Hess, Kenneth R, Varadhachary, Gauri R, Amir Habra, Mouhammed
Published in Journal for immunotherapy of cancer (01.03.2020)
Published in Journal for immunotherapy of cancer (01.03.2020)
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Journal Article
Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences
Yao, Shuyang, Meric-Bernstam, Funda, Hong, David, Janku, Filip, Naing, Aung, Piha-Paul, Sarina Anne, Tsimberidou, Apostolia Maria, Karp, Daniel, Subbiah, Vivek, Yap, Timothy Anthony, Ahnert, Jordi Rodon, Pant, Shubham, Dumbrava, Ecaterina E Ileana, Wathoo, Chetna, Campbell, Erick, Yu, Lihou, Yamamura, Yuko, Fu, Siqing
Published in Scientific reports (24.05.2022)
Published in Scientific reports (24.05.2022)
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Journal Article
Limited Independent Follow-Up with Germline Testing of Variants Detected in BRCA1 and BRCA2 by Tumor-Only Sequencing
Nowlen, Carol J, Daniels, Molly, Uzunparmak, Burak, Ileana Dumbrava, Ecaterina E, Yuan, Ying, Patel, Keyur P, Rayes, Nadine, Harkenrider, Jacqueline, Wathoo, Chetna, Veazie, Jennifer, Luna, Krystle A, Wang, Wanlin, Horombe, Chacha, Javle, Milind, Ahnert, Jordi Rodon, Yap, Timothy A, Arun, Banu, Lu, Karen H, Meric-Bernstam, Funda
Published in Journal of Immunotherapy and Precision Oncology (01.02.2024)
Published in Journal of Immunotherapy and Precision Oncology (01.02.2024)
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Journal Article
Preclinical study and parallel phase II trial evaluating antisense STAT3 oligonucleotide and checkpoint blockade for advanced pancreatic, non-small cell lung cancer and mismatch repair-deficient colorectal cancer
Tang, Chad, Hartley, Genevieve P, Couillault, Coline, Yuan, Ying, Lin, Heather, Nicholas, Courtney, Srinivasamani, Anupallavi, Dai, James, Dumbrava, Ecaterina E Ileana, Fu, Siqing, Karp, Daniel D, Naing, Aung, Piha-Paul, Sarina A, Rodon Ahnert, Jordi, Pant, Shubham, Subbiah, Vivek, Yap, Timonthy A, Tsimberidou, Apostolia M, Guerrero, Paola, Dhebat, Sarah, Proia, Theresa, Curran, Michael A, Hong, David S
Published in BMJ Oncology (01.07.2024)
Published in BMJ Oncology (01.07.2024)
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Journal Article
Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/PI3K Pathway Alterations and Advanced Solid Malignancies
Subbiah, Vivek, Coleman, Niamh, Piha-Paul, Sarina A, Tsimberidou, Apostolia M, Janku, Filip, Rodon, Jordi, Pant, Shubham, Dumbrava, Ecaterina E Ileana, Fu, Siqing, Hong, David S, Zhang, Shizhen, Sun, Ming, Jiang, Yunfang, Roszik, Jason, Song, Juhee, Yuan, Ying, Meric-Bernstam, Funda, Naing, Aung
Published in Cancer research communications (12.02.2024)
Published in Cancer research communications (12.02.2024)
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Journal Article
Targeting ERBB2 ( HER2 ) Amplification Identified by Next-Generation Sequencing in Patients With Advanced or Metastatic Solid Tumors Beyond Conventional Indications
Dumbrava, Ecaterina E Ileana, Balaji, Kavitha, Raghav, Kanwal, Hess, Kenneth, Javle, Milind, Blum-Murphy, Mariela, Ajani, Jaffer, Kopetz, Scott, Broaddus, Russell, Routbort, Mark, Demirhan, Mehmet, Zheng, Xiaofeng, Pant, Shubham, Tsimberidou, Apostolia M, Subbiah, Vivek, Hong, David S, Rodon, Jordi, Shaw, Kenna M, Piha-Paul, Sarina A, Meric-Bernstam, Funda
Published in JCO precision oncology (2019)
Published in JCO precision oncology (2019)
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Journal Article
Abstract P6-21-04: Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss
Owusu-Brackett, N, Zhao, M, Akcakanat, A, Evans, KW, Yuca, E, Tapia, C, Ileana-Dumbrava, E, Janku, F, Meric-Bernstam, F
Published in Cancer research (Chicago, Ill.) (15.02.2019)
Published in Cancer research (Chicago, Ill.) (15.02.2019)
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Journal Article
390 COM701 (a novel immune checkpoint inhibitor) in patients with advanced solid tumors
Elnaggar, A, Luke, J, Hamilton, E, Chmielowski, B, Ileana-Dumbrava, E, Patnaik, A, Lim, E, Adewoye, A, Hunter, J, Olweny, J, Sharma, M, Sullivan, R, Vaena, D, Rasco, D
Published in International journal of gynecological cancer (01.09.2019)
Published in International journal of gynecological cancer (01.09.2019)
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Journal Article
Expanded analysis of secondary germline findings from matched tumor/normal sequencing identifies additional clinically significant mutations
Dumbrava, E Ileana, Brusco, L, Daniels, M, Wathoo, C, Shaw, K, Lu, K, Zheng, X, Strong, L, Litton, J, Arun, B, Eterovic, A K, Routbort, M, Patel, K, Qi, Yuan, Piha-Paul, S, Subbiah, V, Hong, D, Rodon, J, Kopetz, S, Mendelsohn, J, Mills, G B, Chen, K, Meric-Bernstam, F
Published in JCO precision oncology (2019)
Published in JCO precision oncology (2019)
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Journal Article
A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies
Hegde, Aparna, Jayaprakash, Priyamvada, Couillault, Coline A, Piha-Paul, Sarina, Karp, Daniel, Rodon, Jordi, Pant, Shubham, Fu, Siqing, Dumbrava, Ecaterina E, Yap, Timothy A, Subbiah, Vivek, Bhosale, Priya, Coarfa, Cristian, Higgins, Jack P, Williams, Eric T, Wilson, Thomas F, Lim, JoAnn, Meric-Bernstam, Funda, Sumner, Elizabeth, Zain, Hira, Nguyen, Di, Nguyen, Ly M, Rajapakshe, Kimal, Curran, Michael A, Hong, David S
Published in Clinical cancer research (01.06.2021)
Published in Clinical cancer research (01.06.2021)
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Journal Article
Abstract 974: Phase II trial of the Wee1 inhibitor adavosertib in advanced refractory solid tumors with CCNE1 amplification
Fu, Siqing, Yao, Shuyang, Yuan, Yuan, Previs, Rebecca A., Elias, Anthony D., Carvajal, Richard, George, Thomas J., Yuan, Ying, Yamamura, Yuko, Westin, Shannon, Xing, Yan, Dumbrava, Ecaterina E. Ileana, Karp, Daniel D., Piha-Paul, Sarina A., Tsimberidou, Apostolia M., Rodon, Jordi, Takebe, Naoko, Kunos, Charles, Lu, Karen, Keyomarsi, Khanda, Meric-Bernstam, Funda
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
475P - A phase IIa clinical trial combining ALRN-6924 and palbociclib for the treatment of patients with tumours harboring wild-type p53 and MDM2 amplification or MDM2/CDK4 co-amplification
Meric-Bernstam, F., Somaiah, N., DuBois, S.G., Dumbrava, E E Ileana, Shapiro, G.I., Patel, M.R., Goel, S., Bauer, T., Pinchasik, D., Annis, A., Aivado, M., Vukovic, V., Saleh, M.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
A phase IIa clinical trial combining ALRN-6924 and palbociclib for the treatment of patients with tumours harboring wild-type p53 and MDM2 amplification or MDM2/CDK4 co-amplification
Meric-Bernstam, F., Somaiah, N., DuBois, S.G., Dumbrava, E E Ileana, Shapiro, G.I., Patel, M.R., Goel, S., Bauer, T., Pinchasik, D., Annis, A., Aivado, M., Vukovic, V., Saleh, M.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
475PA phase IIa clinical trial combining ALRN-6924 and palbociclib for the treatment of patients with tumours harboring wild-type p53 and MDM2 amplification or MDM2/CDK4 co-amplification
Meric-Bernstam, F, Somaiah, N, DuBois, S G, Dumbrava, E E Ileana, Shapiro, G I, Patel, M R, Goel, S, Bauer, T, Pinchasik, D, Annis, A, Aivado, M, Vukovic, V, Saleh, M
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article
Abstract CT249: A phase 1b study of nivolumab in patients with autoimmune disorders and advanced malignancies (AIM-NIVO)
Ileana Dumbrava, Ecaterina E., Suarez-Almazor, Maria, Painter, Jeane, Johanns, Tanner M., Dougan, Michael L., Cappelli, Laura, Wang, Yinghong, Bingham, Clifton, Gupta, Sarthak, Warner, Blake M., Rahma, Osama, Naidoo, Jarushka, Ott, Patrick A., Hafler, David A., Kluger, Harriet, Khosroshahi, Arezou, Naqash, Rafeh, Chung, Lorinda, Katsumoto, Tamiko R., Kummar, Shivaani, Tawbi, Hussein, Sharon, Elad
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract PR10: PIK3CA mutations in plasma cell-free DNA predict survival and treatment outcomes in patients with advanced cancers
Ileana Dumbrava, Ecaterina E., Huang, Helen J., Stuckett, Ana, Madwani, Kiran, Adat, Abha, Hong, David S., Piha-Paul, Sarina A., Subbiah, Vivek, Karp, Daniel D., Fu, Siqing, Naing, Aung, Tsimberidou, Apostolia M., Moulder, Stacey, Koenig, Kimberly, Barcenas, Carlos H., Kee, Bryan, Fogelman, David, Kopetz, Scott, Meric-Bernstam, Funda, Janku, Filip
Published in Molecular cancer research (01.10.2020)
Published in Molecular cancer research (01.10.2020)
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Journal Article
1270PPembrolizumab in advanced rare cancers
Naing, A, Meric-Bernstam, F, Karp, D, Rodon, J A, Piha-Paul, S A, Subbiah, V, Hong, D S, Pant, S, Fu, S, Janku, F, Yap, T A, Tsimberidou, A M, Dumbrava, E E Ileana, Colen, R R, Hess, K R, Campbell, M T, Tu, S-M, Jimenez, C, Habra, M A, Varadhachary, G R
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Journal Article