Evolving Landscape of New Drug Approval in Japan and Lags from International Birth Dates: Retrospective Regulatory Analysis
Tanaka, Mototsugu, Idei, Mayumi, Sakaguchi, Hiroshi, Kato, Ryosuke, Sato, Daisuke, Sawanobori, Kenji, Kawarasaki, Shuichi, Hata, Toshiyuki, Yoshizaki, Asako, Nakamura, Miki, Ikuma, Mutsuhiro
Published in Clinical pharmacology and therapeutics (01.05.2021)
Published in Clinical pharmacology and therapeutics (01.05.2021)
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Achievements and challenges of the Sakigake designation system in Japan
Tanaka, Mototsugu, Idei, Mayumi, Sakaguchi, Hiroshi, Kato, Ryosuke, Sato, Daisuke, Sawanobori, Kenji, Kawarasaki, Shuichi, Hata, Toshiyuki, Yoshizaki, Asako, Nakamura, Miki, Ikuma, Mutsuhiro
Published in British journal of clinical pharmacology (01.10.2021)
Published in British journal of clinical pharmacology (01.10.2021)
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Assessment of the impact of Japanese‐specific long‐term safety data on new drug approval
Uzu, Shinobu, Sekine, Shohko, Asano, Junichi, Ikuma, Mutsuhiro
Published in Clinical and translational science (01.11.2021)
Published in Clinical and translational science (01.11.2021)
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A deficiency of gastric interstitial cells of Cajal accompanied by decreased expression of neuronal nitric oxide synthase and substance P in patients with type 2 diabetes mellitus
Iwasaki, Hirohiko, Kajimura, Masayoshi, Osawa, Satoshi, Kanaoka, Shigeru, Furuta, Takahisa, Ikuma, Mutsuhiro, Hishida, Akira
Published in Journal of gastroenterology (01.11.2006)
Published in Journal of gastroenterology (01.11.2006)
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Fecal Cyclooxygenase 2 Plus Matrix Metalloproteinase 7 mRNA Assays as a Marker for Colorectal Cancer Screening
TAKAI, Tetsunari, KANAOKA, Shigeru, YOSHIDA, Ken-Ichi, HAMAYA, Yasushi, IKUMA, Mutsuhiro, MIURA, Naoyuki, SUGIMURA, Haruhiko, KAJIMURA, Masayoshi, HISHIDA, Akira
Published in Cancer epidemiology, biomarkers & prevention (01.06.2009)
Published in Cancer epidemiology, biomarkers & prevention (01.06.2009)
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Characteristics of non-erosive gastroesophageal reflux disease refractory to proton pump inhibitor therapy
Sugimoto, Mitsushige, Nishino, Masafumi, Kodaira, Chise, Yamade, Mihoko, Uotani, Takahiro, Ikuma, Mutsuhiro, Umemura, Kazuo, Furuta, Takahisa
Published in World journal of gastroenterology : WJG (14.04.2011)
Published in World journal of gastroenterology : WJG (14.04.2011)
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Dual therapy with high doses of rabeprazole and amoxicillin versus triple therapy with rabeprazole, amoxicillin, and metronidazole as a rescue regimen for Helicobacter pylori infection after the standard triple therapy
SHIRAI, Naohito, SUGIMOTO, Mitsushige, KODAIRA, Chise, NISHINO, Masafumi, IKUMA, Mutsuhiro, KAJIMURA, Masayoshi, OHASHI, Kyoichi, ISHIZAKI, Takashi, HISHIDA, Akira, FURUTA, Takahisa
Published in European journal of clinical pharmacology (01.08.2007)
Published in European journal of clinical pharmacology (01.08.2007)
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Relationship Between Low-Dose Aspirin-Induced Gastric Mucosal Injury and Intragastric pH in Healthy Volunteers
Nishino, Masafumi, Sugimoto, Mitsushige, Kodaira, Chise, Yamade, Mihoko, Shirai, Naohito, Ikuma, Mutsuhiro, Tanaka, Tatsuo, Sugimura, Haruhiko, Hishida, Akira, Furuta, Takahisa
Published in Digestive diseases and sciences (01.06.2010)
Published in Digestive diseases and sciences (01.06.2010)
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Impact of Acid Inhibition on Esophageal Mucosal Injury Induced by Low-Dose Aspirin
Sugimoto, Mitsushige, Nishino, Masafumi, Kodaira, Chise, Yamade, Mihoko, Uotani, Takahiro, Ikuma, Mutsuhiro, Furuta, Takahisa
Published in Digestion (01.01.2012)
Published in Digestion (01.01.2012)
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Statins directly suppress cytokine production in murine intraepithelial lymphocytes
Zhang, Jiong, Osawa, Satoshi, Takayanagi, Yasuhiro, Ikuma, Mutsuhiro, Yamada, Takanori, Sugimoto, Mitsushige, Furuta, Takahisa, Miyajima, Hiroaki, Sugimoto, Ken
Published in Cytokine (Philadelphia, Pa.) (01.02.2013)
Published in Cytokine (Philadelphia, Pa.) (01.02.2013)
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Influences of Chymase and Angiotensin I-Converting Enzyme Gene Polymorphisms on Gastric Cancer Risks in Japan
SUGIMOTO, Mitsushige, FURUTA, Takahisa, SHIRAI, Naohito, IKUMA, Mutsuhiro, SUGIMURA, Haruhiko, HISHIDA, Akira
Published in Cancer epidemiology, biomarkers & prevention (01.10.2006)
Published in Cancer epidemiology, biomarkers & prevention (01.10.2006)
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Influence of different proton pump inhibitors on activity of cytochrome P450 assessed by [(13)C]-aminopyrine breath test
Kodaira, Chise, Uchida, Shinya, Yamade, Mihoko, Nishino, Masafumi, Ikuma, Mutsuhiro, Namiki, Noriyuki, Sugimoto, Mitsushige, Watanabe, Hiroshi, Hishida, Akira, Furuta, Takahisa
Published in Journal of clinical pharmacology (01.03.2012)
Published in Journal of clinical pharmacology (01.03.2012)
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Cytokine responses of intraepithelial lymphocytes are regulated by histamine H₂ receptor
Takagaki, Kosuke, Osawa, Satoshi, Horio, Yoshiaki, Yamada, Takanori, Hamaya, Yasushi, Takayanagi, Yasuhiro, Furuta, Takahisa, Hishida, Akira, Ikuma, Mutsuhiro
Published in Journal of gastroenterology (01.04.2009)
Published in Journal of gastroenterology (01.04.2009)
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Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers
Nishino, Masafumi, Sugimoto, Mitsushige, Kodaira, Chise, Yamade, Mihoko, Uotani, Takahiro, Shirai, Naohito, Ikuma, Mutsuhiro, Tanaka, Tatsuo, Sugimura, Haruhiko, Hishida, Akira, Furuta, Takahisa
Published in Journal of clinical pharmacology (01.07.2011)
Published in Journal of clinical pharmacology (01.07.2011)
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Polymorphisms of matrix metalloproteinase-7 and chymase are associated with susceptibility to and progression of gastric cancer in Japan
Sugimoto, Mitsushige, Furuta, Takahisa, Kodaira, Chise, Nishino, Masafumi, Yamade, Mihoko, Ikuma, Mutsuhiro, Sugimura, Haruhiko, Hishida, Akira
Published in Journal of gastroenterology (01.10.2008)
Published in Journal of gastroenterology (01.10.2008)
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Guggulsterone, a Plant-Derived Inhibitor of NF-TB, Suppresses CDX2 and COX-2 Expression and Reduces the Viability of Esophageal Adenocarcinoma Cells
Yamada, Takanori, Osawa, Satoshi, Ikuma, Mutsuhiro, Kajimura, Masayoshi, Sugimoto, Mitsushige, Furuta, Takahisa, Iwaizumi, Moriya, Sugimoto, Ken
Published in Digestion (2014)
Published in Digestion (2014)
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