Age-related increase of monoamine oxidase B in amyloid-negative cognitively unimpaired elderly subjects
Sakurai, Keita, Nihashi, Takashi, Kimura, Yasuyuki, Iwata, Kaori, Ikenuma, Hiroshi, Arahata, Yutaka, Okamura, Nobuyuki, Yanai, Kazuhiko, Akagi, Akio, Ito, Kengo, Kato, Takashi, Nakamura, Akinori, group, MULNIAD study
Published in Annals of nuclear medicine (01.08.2022)
Published in Annals of nuclear medicine (01.08.2022)
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Journal Article
Radiosynthesis of [11C]MNS for PET imaging of NLRP3 inflammasome with [11C]nitromethane in one-pot and its evaluation in rat brains
Ogata, Aya, Ikenuma, Hiroshi, Abe, Junichiro, Yamada, Takashi, Hattori, Saori, Ichise, Masanori, Suzuki, Masaaki, Kato, Takashi, Kimura, Yasuyuki
Published in Journal of radioanalytical and nuclear chemistry (01.11.2023)
Published in Journal of radioanalytical and nuclear chemistry (01.11.2023)
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Journal Article
11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent
Suzuki, Keiichi, Koyama, Hiroko, Nakamura, Narumasa, Kimura, Yasuyuki, Ogata, Aya, Ikenuma, Hiroshi, Ishii, Hideki, Zhang, Ming-Rong, Kawamura, Kazunori, Minamimoto, Takafumi, Nagai, Yuji, Katsuki, Hiroshi, Kimura, Tetsuya, Kimura, Nobuyuki, Ichise, Masanori, Kato, Takashi, Ito, Kengo, Suzuki, Masaaki
Published in Bioorganic & medicinal chemistry letters (01.04.2023)
Published in Bioorganic & medicinal chemistry letters (01.04.2023)
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Journal Article
Patterns of Distribution of 18F-THK5351 Positron Emission Tomography in Alzheimer's Disease Continuum
Nihashi, Takashi, Sakurai, Keita, Kato, Takashi, Iwata, Kaori, Kimura, Yasuyuki, Ikenuma, Hiroshi, Yamaoka, Akiko, Takeda, Akinori, Arahata, Yutaka, Washimi, Yukihiko, Suzuki, Keisuke, Bundo, Masahiko, Sakurai, Takashi, Okamura, Nobuyuki, Yanai, Kazuhiko, Ito, Kengo, Nakamura, Akinori
Published in Journal of Alzheimer's disease (04.01.2022)
Published in Journal of Alzheimer's disease (04.01.2022)
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Journal Article
Involvement of inflammation in the medial temporal region in the development of agitation in Alzheimer's disease: an in vivo positron emission tomography study
Yasuno, Fumihiko, Kimura, Yasuyuki, Ogata, Aya, Ikenuma, Hiroshi, Abe, Junichiro, Minami, Hiroyuki, Nihashi, Takashi, Yokoi, Kastunori, Hattori, Saori, Shimoda, Nobuyoshi, Watanabe, Atsushi, Kasuga, Kensaku, Ikeuchi, Takeshi, Takeda, Akinori, Sakurai, Takashi, Ito, Kengo, Kato, Takashi
Published in Psychogeriatrics (01.01.2023)
Published in Psychogeriatrics (01.01.2023)
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Journal Article
Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents
Ogata, Aya, Kimura, Yasuyuki, Ikenuma, Hiroshi, Yamada, Takashi, Abe, Junichiro, Koyama, Hiroko, Suzuki, Masaaki, Ichise, Masanori, Kato, Takashi, Ito, Kengo
Published in Nuclear medicine and biology (01.07.2020)
Published in Nuclear medicine and biology (01.07.2020)
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Journal Article
Noradrenaline transporter PET reflects neurotoxin-induced noradrenaline level decrease in the rat hippocampus
Sakai, Takayuki, Hattori, Saori, Ogata, Aya, Yamada, Takashi, Abe, Junichiro, Ikenuma, Hiroshi, Ichise, Masanori, Suzuki, Masaaki, Ito, Kengo, Kato, Takashi, Kimura, Yasuyuki
Published in EJNMMI research (15.09.2023)
Published in EJNMMI research (15.09.2023)
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Journal Article
A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain
Sakai, Takayuki, Ogata, Aya, Ikenuma, Hiroshi, Yamada, Takashi, Hattori, Saori, Abe, Junichiro, Imamura, Shinichi, Ichise, Masanori, Tada, Mari, Kakita, Akiyoshi, Koyama, Hiroko, Suzuki, Masaaki, Kato, Takashi, Ito, Kengo, Kimura, Yasuyuki
Published in EJNMMI radiopharmacy and chemistry (04.03.2024)
Published in EJNMMI radiopharmacy and chemistry (04.03.2024)
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Journal Article
Trait-anxiety and glial-related neuroinflammation of the amygdala and its associated regions in Alzheimer's disease: A significant correlation
Yasuno, Fumihiko, Kimura, Yasuyuki, Ogata, Aya, Ikenuma, Hiroshi, Abe, Junichiro, Minami, Hiroyuki, Nihashi, Takashi, Yokoi, Kastunori, Hattori, Saori, Shimoda, Nobuyoshi, Watanabe, Atsushi, Kasuga, Kensaku, Ikeuchi, Takeshi, Takeda, Akinori, Sakurai, Takashi, Ito, Kengo, Kato, Takashi
Published in Brain, behavior, & immunity. Health (01.07.2024)
Published in Brain, behavior, & immunity. Health (01.07.2024)
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Journal Article
Synthesis and evaluation of a novel PET ligand, a GSK’963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain
Ikenuma, Hiroshi, Ogata, Aya, Koyama, Hiroko, Ji, Bin, Ishii, Hideki, Yamada, Takashi, Abe, Junichiro, Seki, Chie, Nagai, Yuji, Ichise, Masanori, Minamimoto, Takafumi, Higuchi, Makoto, Zhang, Ming-Rong, Kato, Takashi, Ito, Kengo, Suzuki, Masaaki, Kimura, Yasuyuki
Published in EJNMMI radiopharmacy and chemistry (18.10.2023)
Published in EJNMMI radiopharmacy and chemistry (18.10.2023)
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Journal Article
Estimation of blood-based biomarkers of glial activation related to neuroinflammation
Yasuno, Fumihiko, Watanabe, Atsushi, Kimura, Yasuyuki, Yamauchi, Yumeka, Ogata, Aya, Ikenuma, Hiroshi, Abe, Junichiro, Minami, Hiroyuki, Nihashi, Takashi, Yokoi, Kastunori, Hattori, Saori, Shimoda, Nobuyoshi, Kasuga, Kensaku, Ikeuchi, Takeshi, Takeda, Akinori, Sakurai, Takashi, Ito, Kengo, Kato, Takashi
Published in Brain, behavior, & immunity. Health (01.12.2022)
Published in Brain, behavior, & immunity. Health (01.12.2022)
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Journal Article
[11C]NCGG401, a novel PET ligand for imaging of colony stimulating factor 1 receptors
Ogata, Aya, Ji, Bin, Yamada, Takashi, Hattori, Saori, Abe, Junichiro, Ikenuma, Hiroshi, Ichise, Masanori, Koyama, Hiroko, Suzuki, Masaaki, Kato, Takashi, Ito, Kengo, Kimura, Yasuyuki
Published in Bioorganic & medicinal chemistry letters (01.06.2022)
Published in Bioorganic & medicinal chemistry letters (01.06.2022)
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Journal Article
Neuroimaging biomarkers of glial activation for predicting the annual cognitive function decline in patients with Alzheimer’s disease
Yasuno, Fumihiko, Kimura, Yasuyuki, Ogata, Aya, Ikenuma, Hiroshi, Abe, Junichiro, Minami, Hiroyuki, Nihashi, Takashi, Yokoi, Kastunori, Hattori, Saori, Shimoda, Nobuyoshi, Watanabe, Atsushi, Kasuga, Kensaku, Ikeuchi, Takeshi, Takeda, Akinori, Sakurai, Takashi, Ito, Kengo, Kato, Takashi
Published in Brain, behavior, and immunity (01.11.2023)
Published in Brain, behavior, and immunity (01.11.2023)
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Journal Article
Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in the brain
Ogata, Aya, Yamada, Takashi, Hattori, Saori, Ikenuma, Hiroshi, Abe, Junichiro, Tada, Mari, Ichise, Masanori, Suzuki, Masaaki, Ito, Kengo, Kato, Takashi, Amaike, Kazuma, Hirota, Tsuyoshi, Kakita, Akiyoshi, Itami, Kenichiro, Kimura, Yasuyuki
Published in Bioorganic & medicinal chemistry letters (15.06.2023)
Published in Bioorganic & medicinal chemistry letters (15.06.2023)
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Journal Article
Kinetic modeling and non-invasive approach for translocator protein quantification with 11C-DPA-713
Yasuno, Fumihiko, Kimura, Yasuyuki, Ogata, Aya, Ikenuma, Hiroshi, Abe, Junichiro, Minami, Hiroyuki, Nihashi, Takashi, Yokoi, Kastunori, Hattori, Saori, Shimoda, Nobuyoshi, Ichise, Masanori, Sakurai, Takashi, Ito, Kengo, Kato, Takashi
Published in Nuclear medicine and biology (01.05.2022)
Published in Nuclear medicine and biology (01.05.2022)
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Journal Article
Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an C-11-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-C-11] acetone
Ikenuma, Hiroshi, Koyama, Hiroko, Kajino, Naoya, Kimura, Yasuyuki, Ogata, Aya, Abe, Junichiro, Kawasumi, Yasuhiro, Kato, Takashi, Takashima, Akihiko, Ito, Kengo, Suzuki, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
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Journal Article
Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone
Ikenuma, Hiroshi, Koyama, Hiroko, Kajino, Naoya, Kimura, Yasuyuki, Ogata, Aya, Abe, Junichiro, Kawasumi, Yasuhiro, Kato, Takashi, Takashima, Akihiko, Ito, Kengo, Suzuki, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
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Journal Article
Evaluation of specific binding of [ 11 C]TZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain
Sakai, Takayuki, Yamada, Takashi, Ikenuma, Hiroshi, Ogata, Aya, Ichise, Masanori, Hattori, Saori, Abe, Junichiro, Tada, Mari, Kakita, Akiyoshi, Suzuki, Masaaki, Ito, Kengo, Kato, Takashi, Imamura, Shinichi, Kimura, Yasuyuki
Published in American journal of nuclear medicine and molecular imaging (2024)
Published in American journal of nuclear medicine and molecular imaging (2024)
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Journal Article
Evaluation of specific binding of 11CTZ7774 to the receptor-interacting protein kinase 1 (RIPK1) in the brain
Sakai, Takayuki, Yamada, Takashi, Ikenuma, Hiroshi, Ogata, Aya, Ichise, Masanori, Hattori, Saori, Abe, Junichiro, Tada, Mari, Kakita, Akiyoshi, Suzuki, Masaaki, Ito, Kengo, Kato, Takashi, Imamura, Shinichi, Kimura, Yasuyuki
Published in American journal of nuclear medicine and molecular imaging (01.01.2024)
Published in American journal of nuclear medicine and molecular imaging (01.01.2024)
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Journal Article
Synthesis of PET probe O-6-[(3-[C-11]methyl)benzyl]guanine by Pd-0-mediated rapid C-[C-11]methylation toward imaging DNA repair protein O-6-methylguanine-DNA methyltransferase in glioblastoma
Koyama, Hiroko, Ikenuma, Hiroshi, Toda, Hiroshi, Kondo, Goro, Hirano, Masaki, Kato, Masaya, Abe, Junichiro, Yamada, Takashi, Wakabayashi, Toshihiko, Ito, Kengo, Natsume, Atsushi, Suzuki, Masaaki
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
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Journal Article