Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist
Nishi, Takahide, Miyazaki, Shojiro, Takemoto, Toshiyasu, Suzuki, Keisuke, Iio, Yukiko, Nakajima, Katsuyoshi, Ohnuki, Takashi, Kawase, Yumi, Nara, Futoshi, Inaba, Shinichi, Izumi, Takashi, Yuita, Hiroshi, Oshima, Keiko, Doi, Hiromi, Inoue, Ryotaku, Tomisato, Wataru, Kagari, Takashi, Shimozato, Takaichi
Published in ACS medicinal chemistry letters (12.05.2011)
Published in ACS medicinal chemistry letters (12.05.2011)
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Journal Article
An efficient synthesis of enantiomerically pure 2-[(2 R)-arylmorpholin-2-yl]ethanols, key intermediates of tachykinin receptor antagonist
Nishi, Takahide, Ishibashi, Koki, Nakajima, Katsuyoshi, Iio, Yukiko, Fukazawa, Tetsuya
Published in Tetrahedron: asymmetry (18.09.1998)
Published in Tetrahedron: asymmetry (18.09.1998)
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Journal Article
Asymmetric synthesis of α,α-disubstituted α-amino alcohol derivatives
Iio, Yukiko, Yamaoka, Makoto, Jin, Masayoshi, Nakamura, Yoshitaka, Nishi, Takahide
Published in Tetrahedron: asymmetry (10.02.2011)
Published in Tetrahedron: asymmetry (10.02.2011)
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Journal Article
Discovery of CS-0777: A Potent, Selective, and Orally Active S1P 1 Agonist
Nishi, Takahide, Miyazaki, Shojiro, Takemoto, Toshiyasu, Suzuki, Keisuke, Iio, Yukiko, Nakajima, Katsuyoshi, Ohnuki, Takashi, Kawase, Yumi, Nara, Futoshi, Inaba, Shinichi, Izumi, Takashi, Yuita, Hiroshi, Oshima, Keiko, Doi, Hiromi, Inoue, Ryotaku, Tomisato, Wataru, Kagari, Takashi, Shimozato, Takaichi
Published in ACS medicinal chemistry letters (12.05.2011)
Published in ACS medicinal chemistry letters (12.05.2011)
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Journal Article
Enzymatic desymmetrization of 2-amino-2-methyl-1,3-propanediol: asymmetric synthesis of ( S)- N-Boc- N, O-isopropylidene-α-methylserinal and (4 R)-methyl-4-[2-(thiophen-2-yl)ethyl]oxazolidin-2-one
Tsuji, Takashi, Iio, Yukiko, Takemoto, Toshiyasu, Nishi, Takahide
Published in Tetrahedron: asymmetry (03.10.2005)
Published in Tetrahedron: asymmetry (03.10.2005)
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Journal Article
Asymmetric synthesis of α,α-disubstituted α-amino alcohol derivatives
Nakamura, Tsuyoshi, Tsuji, Takashi, Iio, Yukiko, Miyazaki, Shojiro, Takemoto, Toshiyasu, Nishi, Takahide
Published in Tetrahedron: asymmetry (27.10.2006)
Published in Tetrahedron: asymmetry (27.10.2006)
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Journal Article
Combined tachykinin receptor antagonist: synthesis and stereochemical structure–activity relationships of novel morpholine analogues
Nishi, Takahide, Ishibashi, Koki, Takemoto, Toshiyasu, Nakajima, Katsuyoshi, Fukazawa, Tetsuya, Iio, Yukiko, Itoh, Kazuhiro, Mukaiyama, Osamu, Yamaguchi, Takeshi
Published in Bioorganic & medicinal chemistry letters (07.08.2000)
Published in Bioorganic & medicinal chemistry letters (07.08.2000)
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Journal Article
SPIROPIPERIDINE DERIVATIVES
NISHI, TAKAHIDE, YAMAGUCHI, TAKESHI, TAKEMOTO, TOSHIYASU, IIO, YUKIKO, NAKAJIMA, KATSUYOSHI
Year of Publication 29.07.1999
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Year of Publication 29.07.1999
Patent
Practical methods for the preparation of spiro[benzo[ c]thiophene-1(3 H),4′-piperidine]-(2 S)-oxide by resolution and asymmetric sulfoxidation
Nishi, Takahide, Nakajima, Katsuyoshi, Iio, Yukiko, Ishibashi, Koki, Fukazawa, Tetsuya
Published in Tetrahedron: asymmetry (01.08.1998)
Published in Tetrahedron: asymmetry (01.08.1998)
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Journal Article
Asymmetric synthesis of enantiomerically pure spiro[((2 S)-hydroxy)indane-1,4′-piperidine]
Takemoto, Toshiyasu, Nakajima, Katsuyoshi, Iio, Yukiko, Tamura, Masakazu, Nishi, Takahide
Published in Tetrahedron: asymmetry (07.05.1999)
Published in Tetrahedron: asymmetry (07.05.1999)
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Journal Article
Combined NK1 and NK2 tachykinin receptor antagonists : Synthesis and structure-activity relationships of novel oxazolidine analogues
NISHI, T, FUKAZAWA, T, YAMAGUCHI, T, ISHIBASHI, K, NAKAJIMA, K, SUGIOKA, Y, IIO, Y, KURATA, H, ITOH, K, MUKAIYAMA, O, SATOH, Y
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
Published in Bioorganic & medicinal chemistry letters (22.03.1999)
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Journal Article
Combined NK 1 and NK 2 tachykinin receptor antagonists: Synthesis and structure-activity relationships of novel oxazolidine analogues
Nishi, Takahide, Fukazawa, Tetsuya, Ishibashi, Koki, Nakajima, Katsuyoshi, Sugioka, Yuki, Iio, Yukiko, Kurata, Hitoshi, Itoh, Kazuhiro, Mukaiyama, Osamu, Satoh, Yumiko, Yamaguchi, Takeshi
Published in Bioorganic & medicinal chemistry letters (1999)
Published in Bioorganic & medicinal chemistry letters (1999)
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Journal Article
DERIVATIVES OF SPIROPIPERIDINE
NISHI TAKAHIDE, IIO YUKIKO, YAMAGUCHI TAKESHI, TAKEMOTO TOSHIYASU, NAKAJIMA KATSUYOSHI
Year of Publication 31.05.2007
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Year of Publication 31.05.2007
Patent
SPIROPIPERIDIN-DERIVATE
NISHI, TAKAHIDE, YAMAGUCHI, TAKESHI, TAKEMOTO, TOSHIYASU, IIO, YUKIKO, NAKAJIMA, KATSUYOSHI
Year of Publication 24.06.2004
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Year of Publication 24.06.2004
Patent
Spiropiperidinderivater
NISHI, TAKAHIDE, YAMAGUCHI, TAKESHI, TAKEMOTO, TOSHIYASU, IIO, YUKIKO, NAKAJIMA, KATSUYOSHI
Year of Publication 26.01.2004
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Year of Publication 26.01.2004
Patent