Exosome secretion is a key pathway for clearance of pathological TDP-43
Iguchi, Yohei, Eid, Lara, Parent, Martin, Soucy, Geneviève, Bareil, Christine, Riku, Yuichi, Kawai, Kaori, Takagi, Shinnosuke, Yoshida, Mari, Katsuno, Masahisa, Sobue, Gen, Julien, Jean-Pierre
Published in Brain (London, England : 1878) (01.12.2016)
Published in Brain (London, England : 1878) (01.12.2016)
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Journal Article
Preclinical progression of neurodegenerative diseases
Katsuno, Masahisa, Sahashi, Kentaro, Iguchi, Yohei, Hashizume, Atsushi
Published in Nagoya journal of medical science (01.08.2018)
Published in Nagoya journal of medical science (01.08.2018)
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Journal Article
Aggresome formation and liquid–liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43
Watanabe, Seiji, Inami, Hidekazu, Oiwa, Kotaro, Murata, Yuri, Sakai, Shohei, Komine, Okiru, Sobue, Akira, Iguchi, Yohei, Katsuno, Masahisa, Yamanaka, Koji
Published in Cell death & disease (23.10.2020)
Published in Cell death & disease (23.10.2020)
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Journal Article
Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions
Ishigaki, Shinsuke, Masuda, Akio, Fujioka, Yusuke, Iguchi, Yohei, Katsuno, Masahisa, Shibata, Akihide, Urano, Fumihiko, Sobue, Gen, Ohno, Kinji
Published in Scientific reports (24.07.2012)
Published in Scientific reports (24.07.2012)
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Journal Article
Loss of TDP-43 causes age-dependent progressive motor neuron degeneration
IGUCHI, Yohei, KATSUNO, Masahisa, MISAWA, Hidemi, SASAKI, Shoichi, TANAKA, Fumiaki, SOBUE, Gen, NIWA, Jun-Ichi, TAKAGI, Shinnosuke, ISHIGAKI, Shinsuke, IKENAKA, Kensuke, KAWAI, Kaori, WATANABE, Hirohisa, YAMANAKA, Koji, TAKAHASHI, Ryosuke
Published in Brain (London, England : 1878) (01.05.2013)
Published in Brain (London, England : 1878) (01.05.2013)
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Journal Article
Therapeutic monoclonal antibody targeting of neuronal pentraxin receptor to control metastasis in gastric cancer
Kanda, Mitsuro, Shimizu, Dai, Sawaki, Koichi, Nakamura, Shunsuke, Umeda, Shinichi, Miwa, Takashi, Tanaka, Haruyoshi, Tanaka, Chie, Hayashi, Masamichi, Iguchi, Yohei, Yamada, Suguru, Katsuno, Masahisa, Kodera, Yasuhiro
Published in Molecular cancer (26.08.2020)
Published in Molecular cancer (26.08.2020)
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Journal Article
Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells
Kanda, Mitsuro, Shimizu, Dai, Nakamura, Shunsuke, Sawaki, Koichi, Umeda, Shinichi, Miwa, Takashi, Tanaka, Haruyoshi, Inokawa, Yoshikuni, Hattori, Norifumi, Hayashi, Masamichi, Tanaka, Chie, Nakayama, Goro, Iguchi, Yohei, Katsuno, Masahisa, Kodera, Yasuhiro
Published in Oncogene (09.09.2021)
Published in Oncogene (09.09.2021)
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Journal Article
Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis
Ikenaka, Kensuke, Ishigaki, Shinsuke, Iguchi, Yohei, Kawai, Kaori, Fujioka, Yusuke, Yokoi, Satoshi, Abdelhamid, Rehab F, Nagano, Seiichi, Mochizuki, Hideki, Katsuno, Masahisa, Sobue, Gen
Published in Journal of neuropathology and experimental neurology (01.04.2020)
Published in Journal of neuropathology and experimental neurology (01.04.2020)
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Journal Article
Exploring the factors underlying remyelination arrest by studying the post‐transcriptional regulatory mechanisms of cystatin F gene
Li, Jiayi, Durose, Wilaiwan Wisessmith, Ito, Junko, Kakita, Akiyoshi, Iguchi, Yohei, Katsuno, Masahisa, Kunisawa, Kazuo, Shimizu, Takeshi, Ikenaka, Kazuhiro
Published in Journal of neurochemistry (01.06.2021)
Published in Journal of neurochemistry (01.06.2021)
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Journal Article
Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
Riku, Yuichi, Seilhean, Danielle, Duyckaerts, Charles, Boluda, Susana, Iguchi, Yohei, Ishigaki, Shinsuke, Iwasaki, Yasushi, Yoshida, Mari, Sobue, Gen, Katsuno, Masahisa
Published in International journal of molecular sciences (08.04.2021)
Published in International journal of molecular sciences (08.04.2021)
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Journal Article
Amyotrophic lateral sclerosis: an update on recent genetic insights
Iguchi, Yohei, Katsuno, Masahisa, Ikenaka, Kensuke, Ishigaki, Shinsuke, Sobue, Gen
Published in Journal of neurology (01.11.2013)
Published in Journal of neurology (01.11.2013)
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Journal Article
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA
Tsuiji, Hitomi, Iguchi, Yohei, Furuya, Asako, Kataoka, Ayane, Hatsuta, Hiroyuki, Atsuta, Naoki, Tanaka, Fumiaki, Hashizume, Yoshio, Akatsu, Hiroyasu, Murayama, Shigeo, Sobue, Gen, Yamanaka, Koji
Published in EMBO molecular medicine (01.02.2013)
Published in EMBO molecular medicine (01.02.2013)
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Journal Article
TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets
Araki, Kunihiko, Araki, Amane, Honda, Daiyu, Izumoto, Takako, Hashizume, Atsushi, Hijikata, Yasuhiro, Yamada, Shinichiro, Iguchi, Yohei, Hara, Akitoshi, Ikumi, Kazuhiro, Kawai, Kaori, Ishigaki, Shinsuke, Nakamichi, Yoko, Tsunekawa, Shin, Seino, Yusuke, Yamamoto, Akiko, Takayama, Yasunori, Hidaka, Shihomi, Tominaga, Makoto, Ohara-Imaizumi, Mica, Suzuki, Atsushi, Ishiguro, Hiroshi, Enomoto, Atsushi, Yoshida, Mari, Arima, Hiroshi, Muramatsu, Shin-Ichi, Sobue, Gen, Katsuno, Masahisa
Published in The Journal of clinical investigation (01.09.2019)
Published in The Journal of clinical investigation (01.09.2019)
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Journal Article
Alterations in the blood–spinal cord barrier in TDP-43 conditional knockout mice
Sasaki, Shoichi, Iguchi, Yohei, Katsuno, Masahisa, Sobue, Gen
Published in Neuroscience letters (26.06.2015)
Published in Neuroscience letters (26.06.2015)
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Journal Article
Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes
Ishigaki, Shinsuke, Fujioka, Yusuke, Okada, Yohei, Riku, Yuichi, Udagawa, Tsuyoshi, Honda, Daiyu, Yokoi, Satoshi, Endo, Kuniyuki, Ikenaka, Kensuke, Takagi, Shinnosuke, Iguchi, Yohei, Sahara, Naruhiko, Takashima, Akihiko, Okano, Hideyuki, Yoshida, Mari, Warita, Hitoshi, Aoki, Masashi, Watanabe, Hirohisa, Okado, Haruo, Katsuno, Masahisa, Sobue, Gen
Published in Cell reports (Cambridge) (31.01.2017)
Published in Cell reports (Cambridge) (31.01.2017)
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Journal Article
Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies
Iguchi, Yohei, Katsuno, Masahisa, Takagi, Shinnosuke, Ishigaki, Shinsuke, Niwa, Jun-ichi, Hasegawa, Masato, Tanaka, Fumiaki, Sobue, Gen
Published in Neurobiology of disease (01.03.2012)
Published in Neurobiology of disease (01.03.2012)
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Journal Article
Reliability and consistency of the Japanese version of the Primary Lateral Sclerosis Functional Rating Scale
Yanagihashi, Masaru, Hirayama, Takehisa, Shibukawa, Mari, Nagasawa, Junpei, Fujita, Koji, Izumi, Yuishin, Morita, Mitsuya, Bokuda, Kota, Takahashi, Kazushi, Kanai, Kazuaki, Atsuta, Naoki, Iguchi, Yohei, Katsuno, Masahisa, Murakami, Yoshitaka, Mitsumoto, Hiroshi, Kano, Osamu
Published in BMC neurology (13.08.2024)
Published in BMC neurology (13.08.2024)
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Journal Article
The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis
Tanaka, Hirotaka, Shimazawa, Masamitsu, Kimura, Masataka, Takata, Masafumi, Tsuruma, Kazuhiro, Yamada, Mitsunori, Takahashi, Hitoshi, Hozumi, Isao, Niwa, Jun-ichi, Iguchi, Yohei, Nikawa, Takeshi, Sobue, Gen, Inuzuka, Takashi, Hara, Hideaki
Published in Scientific reports (13.08.2012)
Published in Scientific reports (13.08.2012)
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Journal Article