Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers
Fagnan, Alexandre, Bagger, Frederik Otzen, Piqué-Borràs, Maria-Riera, Ignacimouttou, Cathy, Caulier, Alexis, Lopez, Cécile K., Robert, Elie, Uzan, Benjamin, Gelsi-Boyer, Véronique, Aid, Zakia, Thirant, Cécile, Moll, Ute, Tauchmann, Samantha, Kurtovic-Kozaric, Amina, Maciejewski, Jaroslaw, Dierks, Christine, Spinelli, Orietta, Salmoiraghi, Silvia, Pabst, Thomas, Shimoda, Kazuya, Deleuze, Virginie, Lapillonne, Hélène, Sweeney, Connor, De Mas, Véronique, Leite, Betty, Kadri, Zahra, Malinge, Sébastien, de Botton, Stéphane, Micol, Jean-Baptiste, Kile, Benjamin, Carmichael, Catherine L., Iacobucci, Ilaria, Mullighan, Charles G., Carroll, Martin, Valent, Peter, Bernard, Olivier A., Delabesse, Eric, Vyas, Paresh, Birnbaum, Daniel, Anguita, Eduardo, Garçon, Loïc, Soler, Eric, Schwaller, Juerg, Mercher, Thomas
Published in Blood (06.08.2020)
Published in Blood (06.08.2020)
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ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia
Thirant, Cécile, Ignacimouttou, Cathy, Lopez, Cécile K., Diop, M’Boyba, Le Mouël, Lou, Thiollier, Clarisse, Siret, Aurélie, Dessen, Phillipe, Aid, Zakia, Rivière, Julie, Rameau, Philippe, Lefebvre, Céline, Khaled, Mehdi, Leverger, Guy, Ballerini, Paola, Petit, Arnaud, Raslova, Hana, Carmichael, Catherine L., Kile, Benjamin T., Soler, Eric, Crispino, John D., Wichmann, Christian, Pflumio, Françoise, Schwaller, Jürg, Vainchenker, William, Lobry, Camille, Droin, Nathalie, Bernard, Olivier A., Malinge, Sébastien, Mercher, Thomas
Published in Cancer cell (13.03.2017)
Published in Cancer cell (13.03.2017)
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Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models
Thiollier, Clarisse, Lopez, Cécile K, Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M'boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D, Ballerini, Paola, Bernard, Olivier A, Pflumio, Françoise, Mercher, Thomas
Published in The Journal of experimental medicine (22.10.2012)
Published in The Journal of experimental medicine (22.10.2012)
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The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300‐dependent stemness program
Fagnan, Alexandre, Aid, Zakia, Baille, Marie, Drakul, Aneta, Robert, Elie, Lopez, Cécile K., Thirant, Cécile, Lecluse, Yann, Rivière, Julie, Ignacimouttou, Cathy, Salmoiraghi, Silvia, Anguita, Eduardo, Naimo, Audrey, Marzac, Christophe, Pflumio, Françoise, Malinge, Sébastien, Wichmann, Christian, Huang, Yun, Lobry, Camille, Chaumeil, Julie, Soler, Eric, Bourquin, Jean‐Pierre, Nerlov, Claus, Bernard, Olivier A., Schwaller, Juerg, Mercher, Thomas
Published in HemaSphere (01.06.2024)
Published in HemaSphere (01.06.2024)
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Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models
Rivera-Munoz, Paola, Laurent, Anouchka P., Siret, Aurelie, Lopez, Cecile K., Ignacimouttou, Cathy, Cornejo, Melanie G., Bawa, Olivia, Rameau, Philippe, Bernard, Olivier A., Dessen, Philippe, Gilliland, Gary D., Mercher, Thomas, Malinge, Sébastien
Published in Blood advances (10.07.2018)
Published in Blood advances (10.07.2018)
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Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia
Laurent, Anouchka P, Siret, Aurélie, Ignacimouttou, Cathy, Panchal, Kunjal, Diop, M'Boyba, Jenni, Silvia, Tsai, Yi-Chien, Roos-Weil, Damien, Aid, Zakia, Prade, Nais, Lagarde, Stephanie, Plassard, Damien, Pierron, Gaelle, Daudigeos, Estelle, Lecluse, Yann, Droin, Nathalie, Bornhauser, Beat C, Cheung, Laurence C, Crispino, John D, Gaudry, Muriel, Bernard, Olivier A, Macintyre, Elizabeth, Barin Bonnigal, Carole, Kotecha, Rishi S, Geoerger, Birgit, Ballerini, Paola, Bourquin, Jean-Pierre, Delabesse, Eric, Mercher, Thomas, Malinge, Sebastien
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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ETO2-GLIS2 Controls Differentiation Arrest and Self-Renewal through Aberrant Enhancers Regulation in Pediatric Leukemia
Thirant, Cecile, Lopez, Cecile K, Ignacimouttou, Cathy, Diop, M'Boyba, Le Mouël, Lou, Thiollier, Clarisse, Siret, Aurelie, Dessen, Philippe, Aid, Zakia, Riviere, Julie, Rameau, Philippe, Lefebvre, Celine, Khaled, Mehdi, Leverger, Guy, Ballerini, Paola Fabiola, Petit, Arnaud, Raslova, Hana, Carmichael, Catherine, Kile, Benjamin T., Soler, Eric, Crispino, John, Wichmann, Christian, Lobry, Camille, Pfumio, Francoise, Schwaller, Juerg, Droin, Nathalie M., Vainchenker, William, Bernard, Olivier A., Malinge, Sebastien, Mercher, Thomas
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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