NOXA upregulation by the prohibitin‐binding compound fluorizoline is transcriptionally regulated by integrated stress response‐induced ATF3 and ATF4
Núñez‐Vázquez, Sonia, Sánchez‐Vera, Ismael, Saura‐Esteller, José, Cosialls, Ana M., Noisier, Anaïs F.M., Albericio, Fernando, Lavilla, Rodolfo, Pons, Gabriel, Iglesias‐Serret, Daniel, Gil, Joan
Published in The FEBS journal (01.02.2021)
Published in The FEBS journal (01.02.2021)
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A Trifluorinated Thiazoline Scaffold Leading to Pro-apoptotic Agents Targeting Prohibitins
Pérez-Perarnau, Alba, Preciado, Sara, Palmeri, Claudia Mariela, Moncunill-Massaguer, Cristina, Iglesias-Serret, Daniel, González-Gironès, Diana M., Miguel, Miriam, Karasawa, Satoki, Sakamoto, Satoshi, Cosialls, Ana M., Rubio-Patiño, Camila, Saura-Esteller, José, Ramón, Rosario, Caja, Laia, Fabregat, Isabel, Pons, Gabriel, Handa, Hiroshi, Albericio, Fernando, Gil, Joan, Lavilla, Rodolfo
Published in Angewandte Chemie (International ed.) (15.09.2014)
Published in Angewandte Chemie (International ed.) (15.09.2014)
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The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax
Cosialls, Ana M, Pomares, Helena, Iglesias-Serret, Daniel, Saura-Esteller, José, Núñez-Vázquez, Sonia, González-Gironès, Diana M, de la Banda, Esmeralda, Preciado, Sara, Albericio, Fernando, Lavilla, Rodolfo, Pons, Gabriel, González-Barca, Eva M, Gil, Joan
Published in Haematologica (Roma) (01.09.2017)
Published in Haematologica (Roma) (01.09.2017)
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A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
Moncunill-Massaguer, Cristina, Saura-Esteller, José, Pérez-Perarnau, Alba, Palmeri, Claudia Mariela, Núñez-Vázquez, Sonia, Cosialls, Ana M, González-Gironès, Diana M, Pomares, Helena, Korwitz, Anne, Preciado, Sara, Albericio, Fernando, Lavilla, Rodolfo, Pons, Gabriel, Langer, Thomas, Iglesias-Serret, Daniel, Gil, Joan
Published in Oncotarget (08.12.2015)
Published in Oncotarget (08.12.2015)
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Targeting prohibitins induces apoptosis in acute myeloid leukemia cells
Pomares, Helena, Palmeri, Claudia M, Iglesias-Serret, Daniel, Moncunill-Massaguer, Cristina, Saura-Esteller, José, Núñez-Vázquez, Sonia, Gamundi, Enric, Arnan, Montserrat, Preciado, Sara, Albericio, Fernando, Lavilla, Rodolfo, Pons, Gabriel, González-Barca, Eva M, Cosialls, Ana M, Gil, Joan
Published in Oncotarget (04.10.2016)
Published in Oncotarget (04.10.2016)
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Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and -independent pathways in B-cell chronic lymphocytic leukemia cells: role of protein kinase Cβ
Barragán, Montserrat, de Frias, Mercè, Iglesias-Serret, Daniel, Campàs, Clara, Castaño, Esther, Santidrián, Antonio F, Coll-Mulet, Llorenç, Cosialls, Ana M, Domingo, Alicia, Pons, Gabriel, Gil, Joan
Published in Journal of leukocyte biology (01.12.2006)
Published in Journal of leukocyte biology (01.12.2006)
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Akt inhibitors induce apoptosis in chronic lymphocytic leukemia cells
DE FRIAS, Mercè, IGLESIAS-SERRET, Daniel, COSIALLS, Ana M, COLL-MULET, Llorenç, SANTIDRIAN, Antonio F, GONZALEZ-GIRONES, Diana M, DE LA BANDA, Esmeralda, PONS, Gabriel, GIL, Joan
Published in Haematologica (Roma) (01.12.2009)
Published in Haematologica (Roma) (01.12.2009)
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Purine Nucleotide Alterations in Tumoral Cell Lines Maintained with Physiological Levels of Folic Acid
Cano-Estrada, Claudia, de Benito-Gómez, Lidia, Escudero-Ferruz, Paula, Ontiveros, Neus, Iglesias-Serret, Daniel, López, José M
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
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The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI
Sánchez-Vera, Ismael, Núñez-Vázquez, Sonia, Saura-Esteller, José, Cosialls, Ana M, Heib, Judith, Nadal Rodríguez, Pau, Ghashghaei, Ouldouz, Lavilla, Rodolfo, Pons, Gabriel, Gil, Joan, Iglesias-Serret, Daniel
Published in International journal of molecular sciences (29.04.2023)
Published in International journal of molecular sciences (29.04.2023)
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Activated ERBB2/HER2 Licenses Sensitivity to Apoptosis upon Endoplasmic Reticulum Stress through a PERK-Dependent Pathway
MARTIN-PEREZ, Rosa, PALACIOS, Carmen, YERBES, Rosario, CANO-GONZALEZ, Ana, IGLESIAS-SERRET, Daniel, GIL, Joan, REGINATO, Mauricio J, LOPEZ-RIVAS, Abelardo
Published in Cancer research (Chicago, Ill.) (15.03.2014)
Published in Cancer research (Chicago, Ill.) (15.03.2014)
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The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells
Cosialls, Ana M., Sánchez-Vera, Ismael, Pomares, Helena, Perramon-Andújar, Judit, Sanchez-Esteban, Sandra, Palmeri, Claudia M., Iglesias-Serret, Daniel, Saura-Esteller, José, Núñez-Vázquez, Sonia, Lavilla, Rodolfo, González-Barca, Eva M., Pons, Gabriel, Gil, Joan
Published in Biochemical pharmacology (01.10.2020)
Published in Biochemical pharmacology (01.10.2020)
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Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines
Saura-Esteller, José, Sánchez-Vera, Ismael, Núñez-Vázquez, Sonia, Cosialls, Ana M., Gama-Pérez, Pau, Bhosale, Gauri, Mendive-Tapia, Lorena, Lavilla, Rodolfo, Pons, Gabriel, Garcia-Roves, Pablo M., Duchen, Michael R., Iglesias-Serret, Daniel, Gil, Joan
Published in International journal of molecular sciences (06.06.2021)
Published in International journal of molecular sciences (06.06.2021)
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The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells
Núñez-Vázquez, Sonia, Saura-Esteller, José, Sánchez-Vera, Ismael, Guilbaud, Emma, Cosialls, Ana M., Pons, Gabriel, Ricci, Jean-Ehrland, Iglesias-Serret, Daniel, Marchetti, Sandrine, Gil, Joan
Published in Oncogenesis (New York, NY) (27.09.2021)
Published in Oncogenesis (New York, NY) (27.09.2021)
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Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells
Cano-González, Ana, Mauro-Lizcano, Marta, Iglesias-Serret, Daniel, Gil, Joan, López-Rivas, Abelardo
Published in Cell death & disease (26.01.2018)
Published in Cell death & disease (26.01.2018)
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Bcl-2 inhibitors induce apoptosis in chronic lymphocytic leukemia cells
Campàs, Clara, Cosialls, Ana M., Barragán, Montserrat, Iglesias-Serret, Daniel, Santidrián, Antonio F., Coll-Mulet, Llorenç, de Frias, Mercè, Domingo, Alicia, Pons, Gabriel, Gil, Joan
Published in Experimental hematology (01.12.2006)
Published in Experimental hematology (01.12.2006)
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Multiplex ligation‐dependent probe amplification for detection of genomic alterations in chronic lymphocytic leukaemia
Coll‐Mulet, Llorenç, Santidrián, Antonio F., Cosialls, Ana M., Iglesias‐Serret, Daniel, De Frias, Mercè, Grau, Javier, Menoyo, Anna, González‐Barca, Eva, Pons, Gabriel, Domingo, Alicia, Gil, Joan
Published in British journal of haematology (01.09.2008)
Published in British journal of haematology (01.09.2008)
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Transcriptional and translational control of Mcl-1 during apoptosis
Iglesias-Serret, Daniel, Piqué, Maria, Gil, Joan, Pons, Gabriel, López, José M
Published in Archives of biochemistry and biophysics (15.09.2003)
Published in Archives of biochemistry and biophysics (15.09.2003)
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Analysis of apoptosis regulatory genes altered by histone deacetylase inhibitors in chronic lymphocytic leukemia cells
Pérez-Perarnau, Alba, Coll-Mulet, Llorenç, Rubio-Patiño, Camila, Iglesias-Serret, Daniel, Cosialls, Ana M., González-Gironès, Diana M., de Frias, Mercè, de Sevilla, Alberto Fernández, de la Banda, Esmeralda, Pons, Gabriel, Gil, Joan
Published in Epigenetics (01.10.2011)
Published in Epigenetics (01.10.2011)
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Isoform‐selective phosphoinositide 3‐kinase inhibitors induce apoptosis in chronic lymphocytic leukaemia cells
De Frias, Mercè, Iglesias‐Serret, Daniel, Cosialls, Ana M., González‐Gironès, Diana M., Pérez‐Perarnau, Alba, Rubio‐Patiño, Camila, Rückle, Thomas, Camps, Montserrat, De Sevilla, Alberto Fernández, De La Banda, Esmeralda, Pons, Gabriel, Gil, Joan
Published in British journal of haematology (01.07.2010)
Published in British journal of haematology (01.07.2010)
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The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells
Santidrian, Antonio F, Cosialls, Ana M, Coll-Mulet, Llorenc, Iglesias-Serret, Daniel, de Frias, Merce, Gonzalez-Girones, Diana M, Campas, Clara, Domingo, Alicia, Pons, Gabriel, Gil, Joan
Published in Haematologica (Roma) (01.12.2007)
Published in Haematologica (Roma) (01.12.2007)
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