Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability
Rizzardi, Lindsay F, Hickey, Peter F, Rodriguez DiBlasi, Varenka, Tryggvadóttir, Rakel, Callahan, Colin M, Idrizi, Adrian, Hansen, Kasper D, Feinberg, Andrew P
Published in Nature neuroscience (01.02.2019)
Published in Nature neuroscience (01.02.2019)
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Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits
Rizzardi, Lindsay F, Hickey, Peter F, Idrizi, Adrian, Tryggvadóttir, Rakel, Callahan, Colin M, Stephens, Kimberly E, Taverna, Sean D, Zhang, Hao, Ramazanoglu, Sinan, Hansen, Kasper D, Feinberg, Andrew P
Published in Genome Biology (22.04.2021)
Published in Genome Biology (22.04.2021)
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Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation
Wulfridge, Phillip, Davidovich, Adam, Salvador, Anna C, Manno, Gabrielle C, Tryggvadottir, Rakel, Idrizi, Adrian, Huda, M Nazmul, Bennett, Brian J, Adams, L Garry, Hansen, Kasper D, Threadgill, David W, Feinberg, Andrew P
Published in PLoS genetics (23.10.2023)
Published in PLoS genetics (23.10.2023)
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A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML
Koldobskiy, Michael A., Abante, Jordi, Jenkinson, Garrett, Pujadas, Elisabet, Tetens, Ashley, Zhao, Feifei, Tryggvadottir, Rakel, Idrizi, Adrian, Reinisch, Andreas, Majeti, Ravindra, Goutsias, John, Feinberg, Andrew P.
Published in Epigenetics (02.08.2020)
Published in Epigenetics (02.08.2020)
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Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis
Koldobskiy, Michael A, Jenkinson, Garrett, Abante, Jordi, Rodriguez DiBlasi, Varenka A, Zhou, Weiqiang, Pujadas, Elisabet, Idrizi, Adrian, Tryggvadottir, Rakel, Callahan, Colin, Bonifant, Challice L, Rabin, Karen R, Brown, Patrick A, Ji, Hongkai, Goutsias, John, Feinberg, Andrew P
Published in Nature biomedical engineering (01.04.2021)
Published in Nature biomedical engineering (01.04.2021)
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DIPG-42. MAPPING THE DNA METHYLATION LANDSCAPE OF DIPG REVEALS NOTABLE METHYLOME VARIABILITY RESPONSIVE TO PHARMACOLOGIC MODULATION
Tetens, Ashley, Martin, Allison, Arnold, Antje, Novak, Orlandi, Idrizi, Adrian, Tryggvadottir, Rakel, Craig-Schwartz, Jordyn, Barbato, Michael, Eberhart, Charles, Resnick, Adam, Koldobskiy, Michael
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study
Montano, Carolina, Taub, Margaret A, Jaffe, Andrew, Briem, Eirikur, Feinberg, Jason I, Trygvadottir, Rakel, Idrizi, Adrian, Runarsson, Arni, Berndsen, Birna, Gur, Ruben C, Moore, Tyler M, Perry, Rodney T, Fugman, Doug, Sabunciyan, Sarven, Yolken, Robert H, Hyde, Thomas M, Kleinman, Joel E, Sobell, Janet L, Pato, Carlos N, Pato, Michele T, Go, Rodney C, Nimgaonkar, Vishwajit, Weinberger, Daniel R, Braff, David, Gur, Raquel E, Fallin, Margaret Daniele, Feinberg, Andrew P
Published in JAMA psychiatry (Chicago, Ill.) (01.05.2016)
Published in JAMA psychiatry (Chicago, Ill.) (01.05.2016)
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DIPG-58. TARGETING DISORDERED DNA METHYLATION IN DIPG TO CONSTRAIN VARIABILITY AND INDUCE IMMUNE SIGNALING
Tetens, Ashley R, Martin, Allison M, Arnold, Antje, Novak, Orlandi V, Idrizi, Adrian, Tryggvadottir, Rakel, Craig-Schwartz, Jordyn, Liapodimitri, Athanasia, Lunsford, Kayleigh, Barbato, Michael I, Eberhart, Charles G, Resnick, Adam C, Raabe, Eric H, Koldobskiy, Michael A
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Comprehensive DNA Methylation Analysis Indicates That Pancreatic Intraepithelial Neoplasia Lesions Are Acinar-Derived and Epigenetically Primed for Carcinogenesis
Lo, Emily K W, Mears, Brian M, Maurer, H Carlo, Idrizi, Adrian, Hansen, Kasper D, Thompson, Elizabeth D, Hruban, Ralph H, Olive, Kenneth P, Feinberg, Andrew P
Published in Cancer research (Chicago, Ill.) (02.06.2023)
Published in Cancer research (Chicago, Ill.) (02.06.2023)
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DNA methylation is stable during replication and cell cycle arrest
Vandiver, Amy R, Idrizi, Adrian, Rizzardi, Lindsay, Feinberg, Andrew P, Hansen, Kasper D
Published in Scientific reports (09.12.2015)
Published in Scientific reports (09.12.2015)
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DNA methylation landscapes in DIPG reveal methylome variability that can be modified pharmacologically
Tetens, Ashley R, Martin, Allison M, Arnold, Antje, Novak, Orlandi V, Idrizi, Adrian, Tryggvadottir, Rakel, Craig-Schwartz, Jordyn, Liapodimitri, Athanasia, Lunsford, Kayleigh, Barbato, Michael I, Eberhart, Charles G, Resnick, Adam C, Raabe, Eric H, Koldobskiy, Michael A
Published in Neuro-oncology advances (01.01.2024)
Published in Neuro-oncology advances (01.01.2024)
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Long-term impacts of disturbance on nitrogen-cycling bacteria in a New England salt marsh
Bernhard, Anne E, Dwyer, Courtney, Idrizi, Adrian, Bender, Geoffrey, Zwick, Rachel
Published in Frontiers in microbiology (04.02.2015)
Published in Frontiers in microbiology (04.02.2015)
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Journal Article
An information-theory analysis of DNA methylation identifies converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia
Koldobskiy, Michael A., Jenkinson, Garrett, Abante, Jordi, DiBlasi, Varenka A. Rodriguez, Zhou, Weiqiang, Pujadas, Elisabet, Idrizi, Adrian, Tryggvadottir, Rakel, Callahan, Colin, Bonifant, Challice L., Rabin, Karen R., Brown, Patrick A., Ji, Hongkai, Goutsias, John, Feinberg, Andrew P.
Published in Nature biomedical engineering (01.04.2021)
Published in Nature biomedical engineering (01.04.2021)
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Journal Article
Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation
Wulfridge, Phillip, Davidovich, Adam, Salvador, Anna C, Manno, Gabrielle C, Tryggvadottir, Rakel, Idrizi, Adrian, Huda, M Nazmul, Bennett, Brian J, Adams, L Garry, Hansen, Kasper D, Threadgill, David W, Feinberg, Andrew P
Published in bioRxiv : the preprint server for biology (28.04.2023)
Published in bioRxiv : the preprint server for biology (28.04.2023)
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Human brain region-specific variably methylated regions (VMRs) are enriched for heritability of distinct neuropsychiatric traits
Rizzardi, Lindsay F, Hickey, Peter F, Idrizi, Adrian, Rakel Tryggvadóttir, Callahan, Colin M, Stephens, Kimberly E, Taverna, Sean D, Zhang, Hao, Ramazanoglu, Sinan, Consortium, Gtex, Hansen, Kasper D, Feinberg, Andrew P
Published in bioRxiv (02.01.2021)
Published in bioRxiv (02.01.2021)
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Paper
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric disease heritability
Rizzardi, Lindsay, Hickey, Peter, Rodriguez, Varenka, Rakel Tryggvadottir, Callahan, Colin, Idrizi, Adrian, Hansen, Kasper, Feinberg, Andrew P
Published in bioRxiv (24.03.2017)
Published in bioRxiv (24.03.2017)
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