Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma
Bhatia, Shailender, Longino, Natalie V, Miller, Natalie J, Kulikauskas, Rima, Iyer, Jayasri G, Ibrani, Dafina, Blom, Astrid, Byrd, David R, Parvathaneni, Upendra, Twitty, Christopher G, Campbell, Jean S, Le, Mai H, Gargosky, Sharron, Pierce, Robert H, Heller, Richard, Daud, Adil I, Nghiem, Paul
Published in Clinical cancer research (01.02.2020)
Published in Clinical cancer research (01.02.2020)
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Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma
Bhatia, Shailender, Miller, Natalie J, Lu, Hailing, Longino, Natalie V, Ibrani, Dafina, Shinohara, Michi M, Byrd, David R, Parvathaneni, Upendra, Kulikauskas, Rima, Ter Meulen, Jan, Hsu, Frank J, Koelle, David M, Nghiem, Paul
Published in Clinical cancer research (15.02.2019)
Published in Clinical cancer research (15.02.2019)
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Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markers
Afanasiev, Olga K, Yelistratova, Lola, Miller, Natalie, Nagase, Kotaro, Paulson, Kelly, Iyer, Jayasri G, Ibrani, Dafina, Koelle, David M, Nghiem, Paul
Published in Clinical cancer research (01.10.2013)
Published in Clinical cancer research (01.10.2013)
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Extended T-Cell Epitope Landscape in Merkel Cell Polyomavirus Large T and Small T Oncoproteins Identified Uniquely in Patients with Cancer
Hansen, Ulla Kring, Lyngaa, Rikke, Ibrani, Dafina, Church, Candice, Verhaegen, Monique, Dlugosz, Andrzej Antoni, Becker, Jürgen Christian, Straten, Per thor, Nghiem, Paul, Hadrup, Sine Reker
Published in Journal of investigative dermatology (01.01.2022)
Published in Journal of investigative dermatology (01.01.2022)
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T-cell Responses to Oncogenic Merkel Cell Polyomavirus Proteins Distinguish Patients with Merkel Cell Carcinoma from Healthy Donors
LYNGAA, Rikke, PEDERSEN, Natasja Wulff, SCHRAMA, David, THRUE, Charlotte Albaek, IBRANI, Dafina, MET, Özcan, PER THOR STRATEN, NGHIEM, Paul, BECKER, Jürgen C, HADRUP, Sine Reker
Published in Clinical cancer research (01.04.2014)
Published in Clinical cancer research (01.04.2014)
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Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling
Acar, Melih, Jafar-Nejad, Hamed, Takeuchi, Hideyuki, Rajan, Akhila, Ibrani, Dafina, Rana, Nadia A., Pan, Hongling, Haltiwanger, Robert S., Bellen, Hugo J.
Published in Cell (25.01.2008)
Published in Cell (25.01.2008)
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Prevalent and Diverse Intratumoral Oncoprotein-Specific CD8 + T Cells within Polyomavirus-Driven Merkel Cell Carcinomas
Jing, Lichen, Ott, Mariliis, Church, Candice D, Kulikauskas, Rima M, Ibrani, Dafina, Iyer, Jayasri G, Afanasiev, Olga K, Colunga, Aric, Cook, Maclean M, Xie, Hong, Greninger, Alexander L, Paulson, Kelly G, Chapuis, Aude G, Bhatia, Shailender, Nghiem, Paul, Koelle, David M
Published in Cancer immunology research (01.05.2020)
Published in Cancer immunology research (01.05.2020)
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Intratumoral G100, a TLR4 agonist, induces anti-tumor immune responses and tumor regression in patients with Merkel cell carcinoma
Bhatia, Shailender, Miller, Natalie J., Lu, Hailing, Vandeven, Natalie, Ibrani, Dafina, Shinohara, Michi M., Byrd, David R., Parvathaneni, Upendra, Kulikauskas, Rima, Meulen, Janter, Hsu, Frank J., Koelle, David M., Nghiem, Paul
Published in Clinical cancer research (09.08.2018)
Published in Clinical cancer research (09.08.2018)
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Human CD4 + T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain
Longino, Natalie V, Yang, Junbao, Iyer, Jayasri G, Ibrani, Dafina, Chow, I-Ting, Laing, Kerry J, Campbell, Victoria L, Paulson, Kelly G, Kulikauskas, Rima M, Church, Candice D, James, Eddie A, Nghiem, Paul, Kwok, William W, Koelle, David M
Published in Cancer immunology research (01.10.2019)
Published in Cancer immunology research (01.10.2019)
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Pilot trial of intratumoral (IT) G100, a toll-like receptor-4 (TLR4) agonist, in patients (pts) with Merkel cell carcinoma (MCC): Final clinical results and immunologic effects on the tumor microenvironment (TME)
Bhatia, Shailender, Miller, Natalie, Lu, Hailing, Ibrani, Dafina, Shinohara, Michi, Byrd, David R., Parvathaneni, Upendra, Vandeven, Natalie, Kulikauskas, Rima, Ter Meulen, Jan, Hsu, Frank J., Koelle, David M, Ngheim, Paul
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Pilot study of intratumoral G100, toll-like receptor-4 (TLR4) agonist, therapy in patients with Merkel cell carcinoma (MCC)
Bhatia, Shailender, Ibrani, Dafina, Vandeven, Natalie, Miller, Natalie, Shinohara, Michi, Byrd, David, Parvathaneni, Upendra, Shantha, Erica, Afanasiev, Olga K., Donahue, Michael, Koelle, David M, Hsu, Frank James, Nghiem, Paul
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
T-cell responses to oncogenic Merkel cell polyomavirus proteins distinguish Merkel cell carcinoma patients from healthy donors
Lyngaa, Rikke, Pedersen, Natasja Wulff, Schrama, David, Thrue, Charlotte Albæk, Ibrani, Dafina, Met, Özcan, Straten, Per thor, Nghiem, Paul, Becker, Jürgen C., Hadrup, Sine Reker
Published in Clinical cancer research (13.02.2014)
Published in Clinical cancer research (13.02.2014)
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Journal Article
Merkel Polyomavirus-Specific T Cells Fluctuate with Merkel Cell Carcinoma Burden and Express Therapeutically Taraetable PD-1 and Tim-3 Exhaustion Markers
AFANASIEV, Olga K, YELISTRATOVA, Lola, MILLER, Natalie, NAGASE, Kotaro, PAULSON, Kelly, IYER, Jayasri G, IBRANI, Dafina, KOELLE, David M, NGHIEM, Paul
Published in Clinical cancer research (2013)
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Published in Clinical cancer research (2013)
Journal Article
Rumi, a CAP10 domain protein, is a glycosyltransferase that modifies Notch and is required for Notch signaling
Acar, Melih, Jafar-Nejad, Hamed, Takeuchi, Hideyuki, Rajan, Akhila, Ibrani, Dafina, Rana, Nadia A., Pan, Hongling, Haltiwanger, Robert S., Bellen, Hugo J.
Published in Cell (25.01.2008)
Published in Cell (25.01.2008)
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Journal Article
Discovery of CD8 T cell epitopes in Merkel cell polyomavirus through combinatorial encoding with MHC multimers
Lyngaa, Rikke, Pedersen, Natasja W, Schrama, David, Thrue, Charlotte A, Met, Özcan, Ibrani, Dafina, thor Straten, Per, Nghiem, Paul, Becker, Jürgen C, Hadrup, Sine R
Published in Journal for immunotherapy of cancer (07.11.2013)
Published in Journal for immunotherapy of cancer (07.11.2013)
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