Immunotherapies for Aging-Related Neurodegenerative Diseases—Emerging Perspectives and New Targets
Kwon, Somin, Iba, Michiyo, Kim, Changyoun, Masliah, Eliezer
Published in Neurotherapeutics (01.07.2020)
Published in Neurotherapeutics (01.07.2020)
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Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice
Guo, Jing L, Narasimhan, Sneha, Changolkar, Lakshmi, He, Zhuohao, Stieber, Anna, Zhang, Bin, Gathagan, Ronald J, Iba, Michiyo, McBride, Jennifer D, Trojanowski, John Q, Lee, Virginia M Y
Published in The Journal of experimental medicine (14.11.2016)
Published in The Journal of experimental medicine (14.11.2016)
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Journal Article
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
Iba, Michiyo, Guo, Jing L, McBride, Jennifer D, Zhang, Bin, Trojanowski, John Q, Lee, Virginia M-Y
Published in The Journal of neuroscience (16.01.2013)
Published in The Journal of neuroscience (16.01.2013)
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Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections
Iba, Michiyo, McBride, Jennifer D., Guo, Jing L., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Published in Acta neuropathologica (01.09.2015)
Published in Acta neuropathologica (01.09.2015)
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Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains
Boluda, Susana, Iba, Michiyo, Zhang, Bin, Raible, Kevin M., Lee, Virginia M-Y., Trojanowski, John Q.
Published in Acta neuropathologica (01.02.2015)
Published in Acta neuropathologica (01.02.2015)
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Journal Article
α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
Tran, Hien T., Chung, Charlotte Hiu-Yan, Iba, Michiyo, Zhang, Bin, Trojanowski, John Q., Luk, Kelvin C., Lee, Virginia M.Y.
Published in Cell reports (Cambridge) (26.06.2014)
Published in Cell reports (Cambridge) (26.06.2014)
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Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
Iba, Michiyo, Kim, Changyoun, Sallin, Michelle, Kwon, Somin, Verma, Anjali, Overk, Cassia, Rissman, Robert A, Sen, Ranjan, Sen, Jyoti Misra, Masliah, Eliezer
Published in Journal of neuroinflammation (17.07.2020)
Published in Journal of neuroinflammation (17.07.2020)
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Journal Article
Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation
Kim, Changyoun, Spencer, Brian, Rockenstein, Edward, Yamakado, Hodaka, Mante, Michael, Adame, Anthony, Fields, Jerel Adam, Masliah, Deborah, Iba, Michiyo, Lee, He-Jin, Rissman, Robert A, Lee, Seung-Jae, Masliah, Eliezer
Published in Molecular neurodegeneration (09.08.2018)
Published in Molecular neurodegeneration (09.08.2018)
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Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy
Carroll, Jenna C, Iba, Michiyo, Bangasser, Debra A, Valentino, Rita J, James, Michael J, Brunden, Kurt R, Lee, Virginia M-Y, Trojanowski, John Q
Published in The Journal of neuroscience (05.10.2011)
Published in The Journal of neuroscience (05.10.2011)
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Journal Article
P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating
Takeuchi, Hiroki, Iba, Michiyo, Inoue, Haruhisa, Higuchi, Makoto, Takao, Keizo, Tsukita, Kayoko, Karatsu, Yoshiko, Iwamoto, Yumiko, Miyakawa, Tsuyoshi, Suhara, Tetsuya, Trojanowski, John Q, Lee, Virginia M-Y, Takahashi, Ryosuke
Published in PloS one (15.06.2011)
Published in PloS one (15.06.2011)
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Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy
Brunden, Kurt R, Zhang, Bin, Carroll, Jenna, Yao, Yuemang, Potuzak, Justin S, Hogan, Anne-Marie L, Iba, Michiyo, James, Michael J, Xie, Sharon X, Ballatore, Carlo, Smith, 3rd, Amos B, Lee, Virginia M-Y, Trojanowski, John Q
Published in The Journal of neuroscience (13.10.2010)
Published in The Journal of neuroscience (13.10.2010)
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Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies
Kwon, Somin, Iba, Michiyo, Masliah, Eliezer, Kim, Changyoun
Published in Experimental neurobiology (31.10.2019)
Published in Experimental neurobiology (31.10.2019)
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Journal Article
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease
Iba, Michiyo, Kwon, Somin, Kim, Changyoun, Szabo, Marcell, Horan-Portelance, Liam, Lopez-Ocasio, Maria, Dagur, Pradeep, Overk, Cassia, Rissman, Robert A, Masliah, Eliezer
Published in Journal of neuroinflammation (15.04.2024)
Published in Journal of neuroinflammation (15.04.2024)
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Retraction Note: Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits in a mouse model of DLB/PD
Iba, Michiyo, McDevitt, Ross A, Kim, Changyoun, Roy, Roshni, Sarantopoulou, Dimitra, Tommer, Ella, Siegars, Byron, Sallin, Michelle, Kwon, Somin, Sen, Jyoti Misra, Sen, Ranjan, Masliah, Eliezer
Published in Molecular neurodegeneration (16.10.2024)
Published in Molecular neurodegeneration (16.10.2024)
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Journal Article
Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells
Kim, Changyoun, Kwon, Somin, Iba, Michiyo, Spencer, Brian, Rockenstein, Edward, Mante, Michael, Adame, Anthony, Shin, Soo Jean, Fields, Jerel A., Rissman, Robert A., Lee, Seung-Jae, Masliah, Eliezer
Published in Experimental & molecular medicine (01.02.2021)
Published in Experimental & molecular medicine (01.02.2021)
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Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models
Iba, Michiyo, Kim, Changyoun, Florio, Jazmin, Mante, Michael, Adame, Anthony, Rockenstein, Edward, Kwon, Somin, Rissman, Robert, Masliah, Eliezer
Published in Frontiers in neuroscience (31.03.2020)
Published in Frontiers in neuroscience (31.03.2020)
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Journal Article
RETRACTED ARTICLE: Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits in a mouse model of DLB/PD
Iba, Michiyo, McDevitt, Ross A., Kim, Changyoun, Roy, Roshni, Sarantopoulou, Dimitra, Tommer, Ella, Siegars, Byron, Sallin, Michelle, Kwon, Somin, Sen, Jyoti Misra, Sen, Ranjan, Masliah, Eliezer
Published in Molecular neurodegeneration (05.09.2022)
Published in Molecular neurodegeneration (05.09.2022)
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Journal Article
Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies
Kim, Changyoun, Hovakimyan, Armine, Zagorski, Karen, Antonyan, Tatevik, Petrushina, Irina, Davtyan, Hayk, Chailyan, Gor, Hasselmann, Jonathan, Iba, Michiyo, Adame, Anthony, Rockenstein, Edward, Szabo, Marcell, Blurton-Jones, Mathew, Cribbs, David H., Ghochikyan, Anahit, Masliah, Eliezer, Agadjanyan, Michael G.
Published in npj vaccines (10.01.2022)
Published in npj vaccines (10.01.2022)
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Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies
Kim, Changyoun, Hovakimyan, Armine, Zagorski, Karen, Antonyan, Tatevik, Petrushina, Irina, Davtyan, Hayk, Chailyan, Gor, Hasselmann, Jonathan, Iba, Michiyo, Adame, Anthony, Rockenstein, Edward, Szabo, Marcell, Blurton-Jones, Mathew, Cribbs, David H., Ghochikyan, Anahit, Masliah, Eliezer, Agadjanyan, Michael G.
Published in npj vaccines (17.07.2023)
Published in npj vaccines (17.07.2023)
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