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Published in Genome Biology (30.11.2023)
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Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma
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Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes
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Published in Cancer (01.12.2021)
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Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes
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Published in Cancer (01.05.2019)
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Pancreatic cancer biology and genetics from an evolutionary perspective
Makohon-Moore, Alvin, Iacobuzio-Donahue, Christine A.
Published in Nature reviews. Cancer (01.09.2016)
Published in Nature reviews. Cancer (01.09.2016)
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Fumarate hydratase FH c.1431_1433dupAAA (p.Lys477dup) variant is not associated with cancer including renal cell carcinoma
Zhang, Liying, Walsh, Michael F., Jairam, Sowmya, Mandelker, Diana, Zhong, Yi, Kemel, Yelena, Chen, Ying‐Bei, Musheyev, David, Zehir, Ahmet, Jayakumaran, Gowtham, Brzostowski, Edyta, Birsoy, Ozge, Yang, Ciyu, Li, Yirong, Somar, Joshua, DeLair, Deborah, Pradhan, Nisha, Berger, Michael F., Cadoo, Karen, Carlo, Maria I., Robson, Mark E., Stadler, Zsofia K., Iacobuzio‐Donahue, Christine A., Joseph, Vijai, Offit, Kenneth
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Molecular pathways in pancreatic carcinogenesis
Macgregor-Das, Anne M., Iacobuzio-Donahue, Christine A.
Published in Journal of surgical oncology (01.01.2013)
Published in Journal of surgical oncology (01.01.2013)
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GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1
Zhong, Yi, Wang, Zheng, Fu, Baojin, Pan, Fan, Yachida, Shinichi, Dhara, Mousumi, Albesiano, Emilia, Li, Li, Naito, Yoshiki, Vilardell, Felip, Cummings, Christopher, Martinelli, Paola, Li, Ang, Yonescu, Raluca, Ma, Qingyong, Griffin, Constance A, Real, Francisco X, Iacobuzio-Donahue, Christine A
Published in PloS one (19.07.2011)
Published in PloS one (19.07.2011)
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TGF-β Tumor Suppression through a Lethal EMT
David, Charles J., Huang, Yun-Han, Chen, Mo, Su, Jie, Zou, Yilong, Bardeesy, Nabeel, Iacobuzio-Donahue, Christine A., Massagué, Joan
Published in Cell (25.02.2016)
Published in Cell (25.02.2016)
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Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells
Klemm, Florian, Maas, Roeltje R., Bowman, Robert L., Kornete, Mara, Soukup, Klara, Nassiri, Sina, Brouland, Jean-Philippe, Iacobuzio-Donahue, Christine A., Brennan, Cameron, Tabar, Viviane, Gutin, Philip H., Daniel, Roy T., Hegi, Monika E., Joyce, Johanna A.
Published in Cell (25.06.2020)
Published in Cell (25.06.2020)
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The mutational landscape of normal human endometrial epithelium
Moore, Luiza, Leongamornlert, Daniel, Coorens, Tim H. H., Sanders, Mathijs A., Ellis, Peter, Dentro, Stefan C., Dawson, Kevin J., Butler, Tim, Rahbari, Raheleh, Mitchell, Thomas J., Maura, Francesco, Nangalia, Jyoti, Tarpey, Patrick S., Brunner, Simon F., Lee-Six, Henry, Hooks, Yvette, Moody, Sarah, Mahbubani, Krishnaa T., Jimenez-Linan, Mercedes, Brosens, Jan J., Iacobuzio-Donahue, Christine A., Martincorena, Inigo, Saeb-Parsy, Kourosh, Campbell, Peter J., Stratton, Michael R.
Published in Nature (London) (30.04.2020)
Published in Nature (London) (30.04.2020)
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An analysis of genetic heterogeneity in untreated cancers
Reiter, Johannes G., Baretti, Marina, Gerold, Jeffrey M., Makohon-Moore, Alvin P., Daud, Adil, Iacobuzio-Donahue, Christine A., Azad, Nilofer S., Kinzler, Kenneth W., Nowak, Martin A., Vogelstein, Bert
Published in Nature reviews. Cancer (01.11.2019)
Published in Nature reviews. Cancer (01.11.2019)
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Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases
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Published in Science (American Association for the Advancement of Science) (15.06.2018)
Published in Science (American Association for the Advancement of Science) (15.06.2018)
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Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
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Published in Nature genetics (01.03.2017)
Published in Nature genetics (01.03.2017)
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Phase 2 multi‐institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinoma
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Published in Cancer (01.04.2015)
Published in Cancer (01.04.2015)
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Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations
Hu, Zishuo I, Shia, Jinru, Stadler, Zsofia K, Varghese, Anna M, Capanu, Marinela, Salo-Mullen, Erin, Lowery, Maeve A, Diaz, Jr, Luis A, Mandelker, Diana, Yu, Kenneth H, Zervoudakis, Alice, Kelsen, David P, Iacobuzio-Donahue, Christine A, Klimstra, David S, Saltz, Leonard B, Sahin, Ibrahim H, O'Reilly, Eileen M
Published in Clinical cancer research (15.03.2018)
Published in Clinical cancer research (15.03.2018)
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Minimal functional driver gene heterogeneity among untreated metastases
Reiter, Johannes G, Makohon-Moore, Alvin P, Gerold, Jeffrey M, Heyde, Alexander, Attiyeh, Marc A, Kohutek, Zachary A, Tokheim, Collin J, Brown, Alexia, DeBlasio, Rayne M, Niyazov, Juliana, Zucker, Amanda, Karchin, Rachel, Kinzler, Kenneth W, Iacobuzio-Donahue, Christine A, Vogelstein, Bert, Nowak, Martin A
Published in Science (American Association for the Advancement of Science) (07.09.2018)
Published in Science (American Association for the Advancement of Science) (07.09.2018)
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Ordered and deterministic cancer genome evolution after p53 loss
Baslan, Timour, Morris, John P., Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M., Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M., Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J., Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark T. A., Socci, Nicholas D., Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D., Iacobuzio-Donahue, Christine A., Lowe, Scott W.
Published in Nature (London) (25.08.2022)
Published in Nature (London) (25.08.2022)
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