CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi
Hawley, Kelly L, Olson, Chris M., Jr, Iglesias-Pedraz, Juan M, Navasa, Nicolás, Cervantes, Jorge L, Caimano, Melissa J, Izadi, Hooman, Ingalls, Robin R, Pal, Utpal, Salazar, Juan C, Radolf, Justin D, Anguita, Juan
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2012)
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p38 Mitogen-Activated Protein Kinase Controls NF-κB Transcriptional Activation and Tumor Necrosis Factor Alpha Production through RelA Phosphorylation Mediated by Mitogen- and Stress-Activated Protein Kinase 1 in Response to Borrelia burgdorferi Antigens
Olson, Chris M, Hedrick, Michael N, Izadi, Hooman, Bates, Tonya C, Olivera, Elias R, Anguita, Juan
Published in Infection and Immunity (01.01.2007)
Published in Infection and Immunity (01.01.2007)
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Journal Article
c-Jun N-Terminal Kinase 1 Is Required for Toll-Like Receptor 1 Gene Expression in Macrophages
Izadi, Hooman, Motameni, Amirreza T, Bates, Tonya C, Olivera, Elias R, Villar-Suarez, Vega, Joshi, Ila, Garg, Renu, Osborne, Barbara A, Davis, Roger J, Rincón, Mercedes, Anguita, Juan
Published in Infection and Immunity (01.10.2007)
Published in Infection and Immunity (01.10.2007)
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Journal Article
Sgr-2921, a Potent CDC7 Inhibitor, Demonstrates Significant Anti-Leukemic Responses in Patient-Derived AML Models Representing Difficult-to-Treat Disease
Izadi, Hooman, Wang, Hui, Atsriku, Christian, Konst, Zef, Levinson, Adam, Piccotti, Joseph, Pirie-Shepherd, Steven, Tang, Lin, Weiss, Dan, Akinsanya, Karen, Wright, Hamish, Jensen, Kristian K
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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A phase 1/2 dose escalation study of the BCL-2 inhibitor ZN-d5 and the WEE1 inhibitor azenosertib (ZN-c3) in patients (Pts) with acute myeloid leukemia (AML)
Smith, Catherine Choy, Vachhani, Pankit, Garcia-Manero, Guillermo, Grieselhuber, Nicole Renee, Guru Murthy, Guru Subramanian, Bhatia, Astha, Arora, Jatinder, Izadi, Hooman, Fiorino, Anthony, Rampal, Raajit
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Abstract 4707: Evaluation of efficacy and immune response to PD1 checkpoint inhibition in human immune-reconstituted mice using patient-derived xenograft models
Izadi, Hooman, Broudy, Tommy, Yan, Deborah, Thatte, Jayant
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Rumen‐protected l‐carnitine supplementation during mating period altered metabolic status and reproductive performance of ewes
Masoomi, Maziar, Kheirandish, Parisa, Javadmanesh, Ali, Danesh Mesgaran, Sadjad, Izadi, Hooman, Danesh Mesgaran, Mohsen
Published in Journal of animal physiology and animal nutrition (01.03.2024)
Published in Journal of animal physiology and animal nutrition (01.03.2024)
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Journal Article
암에 대한 WEE1 억제제
IZADI HOOMAN, DE JONG PETRUS RUDOLF, BUNKER KEVIN DUANE, HUANG PETER QINHUA, DONATE FERNANDO, SAMATAR AHMED ABDI
Year of Publication 06.08.2024
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Year of Publication 06.08.2024
Patent
복합제
IZADI HOOMAN, PINCHMAN JOSEPH ROBERT, BUNKER KEVIN DUANE, HUANG PETER QINHUA, SAMATAR AHMED ABDI, DONATE FERNANDO
Year of Publication 12.01.2023
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Year of Publication 12.01.2023
Patent
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IZADI HOOMAN, PINCHMAN JOSEPH ROBERT, BUNKER KEVIN DUANE, HUANG PETER QINHUA, SAMATAR AHMED ABDI, DONATE FERNANDO
Year of Publication 29.08.2022
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Year of Publication 29.08.2022
Patent
Abstract 2606: ZN-c3, a potent and selective Wee-1 inhibitor demonstrates anti-tumor activities in combination with other targeted therapies and overcomes PARP inhibitor resistance
Li, Jiali, Ma, Jianhui, de Jong, Petrus R., Izadi, Hooman, Hoang, Tiffany, Ibrahim, Noah, Boren, Brant, Hegde, Sayee Hegde, Doñate, Fernando, Samatar, Ahmed A.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract 2605: BH3 mimetics synergize with the Wee1 inhibitor ZN-c3 by activating caspases which induce DNA damage and degrade key proteins
Izadi, Hooman, Ibrahim, Noah, Hoang, Tiffany, Ma, Jianhui, de Jong, Petrus R., Pinchman, Joseph, Bunker, Kevin D., Samatar, Ahmed A., Doñate, Fernando
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 2591: Combination of the BCL-2 inhibitor ZN-d5 with the WEE1 inhibitor ZN-c3 shows additive or synergistic anti-tumor activity in acute myeloid leukemia (AML) models
Izadi, Hooman, Hoang, Tiffany, Ibrahim, Noah, Pinchman, Joseph, Boren, Brant C., Ma, Jianhui, de Jong, Petrus R., Li, Jiali, Bunker, Kevin D., Samatar, Ahmed A., Doñate, Fernando
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 2811: Comparative study of anti-PD1 and CSF1R inhibition on tumor-infiltrating lymphocytes and macrophage populations across a panel of syngeneic tumor models
Maves, Yuki Kato, Izadi, Hooman, Talaoc, Elvira C., Yan, Deborah, Echegaray, Charlene, Calinisan, Andrew, Moya, Krystal, Venant, Heather, Garland, Mitchell, Iyer, Radhika, Gosh, Shounak, Songco, Stephanie, Thatte, Jayant, Broudy, Tommy
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Regulation of Oxidative Stress by Methylation-Controlled J Protein Controls Macrophage Responses to Inflammatory Insults
Navasa, Nicolás, Martín, Itziar, Iglesias-Pedraz, Juan Manuel, Beraza, Naiara, Atondo, Estíbaliz, Izadi, Hooman, Ayaz, Furkan, Fernández-Álvarez, Sara, Hatle, Ketki, Som, Abhigyam, Dienz, Oliver, Osborne, Barbara A., Martínez-Chantar, Maria Luz, Rincón, Mercedes, Anguita, Juan
Published in The Journal of infectious diseases (01.01.2015)
Published in The Journal of infectious diseases (01.01.2015)
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Abstract 2153: Cyclin E1 protein overexpression sensitizes ovarian cancer cells to ZN-c3, a novel, selective and oral bioavailable inhibitor of Wee1
Ma, Jianhui, Liu, Wen, Chung, Heekyung, Izadi, Hooman, DeJong, Petrus, Harismendy, Olivier, li, Jia, Doñate, Fernando, Samatar, Ahmed, Lackner, Mark, Escoubet, Laure, Bunker, Kevin, Kim, Daehwan, Jameson, Nathan, Ozmen, Tugba Yildiran, Jeong, Kangjin, Zhang, Dong, Pan, Wen-An, Mills, Gordon
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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조합
IZADI HOOMAN, PINCHMAN JOSEPH ROBERT, BOREN BRANT CLAYTON, BUNKER KEVIN DUANE, HUANG PETER QINHUA, SAMATAR AHMED ABDI, DONATE FERNANDO, LI JIALI
Year of Publication 29.08.2022
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Year of Publication 29.08.2022
Patent
조합물
IZADI HOOMAN, PINCHMAN JOSEPH ROBERT, MA JIANHUI, BUNKER KEVIN DUANE, HUANG PETER QINHUA, HEGDE SAYEE GAJANAN, SAMATAR AHMED ABDI, DONATE FERNANDO, LI JIALI
Year of Publication 29.08.2022
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Year of Publication 29.08.2022
Patent
조합
IZADI HOOMAN, PINCHMAN JOSEPH ROBERT, BOREN BRANT CLAYTON, BUNKER KEVIN DUANE, HUANG PETER QINHUA, SAMATAR AHMED ABDI, DONATE FERNANDO, LI JIALI
Year of Publication 29.08.2022
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Year of Publication 29.08.2022
Patent