Pharmacokinetics of fingolimod (FTY720) and a combined oral contraceptive coadministered in healthy women: drug-drug interaction study results
David, Olivier J, Ocwieja, Magdalena, Meiser, Karin, Emotte, Corinne, Jakab, Annamaria, Wemer, Johan, den Daas, Izaak, Schmouder, Robert
Published in International journal of clinical pharmacology and therapeutics (01.08.2012)
Published in International journal of clinical pharmacology and therapeutics (01.08.2012)
Get more information
Journal Article
Development of a pharmacokinetic and pharmacodynamic model for intranasal administration of midazolam in older adults: a single-site two-period crossover study
Barends, Clemens, den Daas, Izaak, Driesens, Mendy, Visser, Anita, Absalom, Anthony, Colin, Pieter
Published in British journal of anaesthesia : BJA (01.08.2023)
Published in British journal of anaesthesia : BJA (01.08.2023)
Get full text
Journal Article
Sampling issues of cerebrospinal fluid and plasma monoamines: Investigation of the circadian rhythm and rostrocaudal concentration gradient
Janssens, Jana, Atmosoerodjo, Sawal D., Vermeiren, Yannick, Absalom, Anthony R., den Daas, Izaak, De Deyn, Peter P.
Published in Neurochemistry international (01.09.2019)
Published in Neurochemistry international (01.09.2019)
Get full text
Journal Article
Modeling the Effect of Excitation on Depth of Anesthesia Monitoring in γ-Aminobutyric Acid Type A Receptor Agonist ABP-700
Valk, Beatrijs I, Eleveld, Douglas J, Meyer, Peter, Meier, Sascha, den Daas, Izaak, van Amsterdam, Kai, Campagna, Jason A, Sweeney, Steven P, Absalom, Anthony R, Struys, Michel M. R F
Published in Anesthesiology (Philadelphia) (01.01.2021)
Published in Anesthesiology (Philadelphia) (01.01.2021)
Get full text
Journal Article
Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action)
Wilkinson, Joanne, Abd-Elaziz, Khalid, den Daas, Izaak, Wemer, Johan, van Haastert, Michiel, Hodgkinson, Victoria, Foster, Michelle, Coyle, Cathal
Published in Drug development and industrial pharmacy (04.03.2019)
Published in Drug development and industrial pharmacy (04.03.2019)
Get more information
Journal Article
A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics–Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a Single Ascending Bolus Dose
Struys, Michel M. R F, Valk, Beatrijs I, Eleveld, Douglas J, Absalom, Anthony R, Meyer, Peter, Meier, Sascha, den Daas, Izaak, Chou, Thomas, van Amsterdam, Kai, Campagna, Jason A, Sweeney, Steven P
Published in Anesthesiology (Philadelphia) (01.07.2017)
Published in Anesthesiology (Philadelphia) (01.07.2017)
Get full text
Journal Article
O1‐12‐05: PHASE 1 STUDY IN HEALTHY VOLUNTEERS OF THE O‐GLCNACASE INHIBITOR ASN120290 AS A NOVEL THERAPY FOR PROGRESSIVE SUPRANUCLEAR PALSY AND RELATED TAUOPATHIES
Ryan, J. Michael, Quattropani, Anna, Abd-Elaziz, Khalid, Daas, Izaak, Schneider, Manfred, Ousson, Solenne, Neny, Maud, Sand, Astrid, Hantson, Jennifer, Permanne, Bruno, Wiessner, Christoph, Beher, Dirk
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
Get full text
Journal Article
Dynamics of neutrophil gelatinase‐associated lipocalin plasma and cerebrospinal fluid concentrations in older males
Naudé, Petrus J. W., Dekens, Doortje W., Eisel, Ulrich L. M., den Daas, Izaak, De Deyn, Peter P.
Published in European journal of clinical investigation (01.12.2017)
Published in European journal of clinical investigation (01.12.2017)
Get full text
Journal Article
Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers
de Boer, Theo, Wieling, Jaap, Meulman, Erik, Reuvers, Mariska, Renkema, Gonda, den Daas, Izaak, van Iersel, Thijs, Wemer, Johan, Chen, LingSing
Published in Biomedical chromatography (01.10.2011)
Published in Biomedical chromatography (01.10.2011)
Get full text
Journal Article
Serial CSF sampling over a period of 30Â h via an indwelling spinal catheter in healthy volunteers: headache, back pain, tolerability and measured acetylcholine profile
Den Daas, Izaak, Wemer, Johan, Abou Farha, Khalid, Tamminga, Wim, de Boer, Theo, Spanjersberg, Rob, Struys, Michel M; R; F, Absalom, Anthony R
Published in European journal of clinical pharmacology (01.05.2013)
Published in European journal of clinical pharmacology (01.05.2013)
Get full text
Journal Article
Serial CSF sampling over a period of 30 h via an indwelling spinal catheter in healthy volunteers: headache, back pain, tolerability and measured acetylcholine profile
den Daas, Izaak, Wemer, Johan, Abou Farha, Khalid, Tamminga, Wim, de Boer, Theo, Spanjersberg, Rob, Struys, Michel M. R. F., Absalom, Anthony R.
Published in European journal of clinical pharmacology (01.05.2013)
Published in European journal of clinical pharmacology (01.05.2013)
Get full text
Journal Article
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Anti-Vwf Nanobody® ALX-0681 After Single and Multiple Subcutaneous Administrations to Healthy Volunteers
Abd-Elaziz, Khalid, Kamphuisen, Pieter W., Lyssens, Christophe, Reuvers, Mariska, den Daas, Izaak, Van Bockstaele, Femke, Vercruysse, Kristof, Ulrichts, Hans, Baumeister, Judith, Crabbe, Patricia, Compernolle, Veerle, Holz, Josefin-Beate
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
Get full text
Journal Article
Orally active carbamate prodrugs of the selective dopamine agonist N-0437: in-vivo activities in the 6-OHDA turning model and in-vitro activities
den Daas, I, de Boer, P, Tepper, P G, Rollema, H, Horn, A S
Published in Journal of pharmacy and pharmacology (01.01.1991)
Published in Journal of pharmacy and pharmacology (01.01.1991)
Get more information
Journal Article
Cloning and characterisation of the human 5‐HT5A serotonin receptor
Rees, Stephen, den Daas, Izaak, Foord, Steven, Goodson, Susannah, Bull, David, Kilpatrick, Gavin, Lee, Melanie
Published in FEBS letters (05.12.1994)
Published in FEBS letters (05.12.1994)
Get full text
Journal Article
A novel series of arylpiperazines with high affinity and selectivity for the dopamine D3 receptor
John Murray, P., Harrison, Lee A., Johnson, Martin R., Robertson, Graeme M., Scopes, David I.C., Bull, David R., Graham, Elizabeth A., Hayes, Ann G., Kilpatrick, Gavin J., Daas, Izaak Den, Large, Charles, Sheehan, Michael J., Stubbs, Carole M., Turpin, Michael P.
Published in Bioorganic & medicinal chemistry letters (02.02.1995)
Published in Bioorganic & medicinal chemistry letters (02.02.1995)
Get full text
Journal Article
A novel series of arylpiperazines with high affinity and selectivity for the dopamine D 3 receptor
John Murray, P., Harrison, Lee A., Johnson, Martin R., Robertson, Graeme M., Scopes, David I.C., Bull, David R., Graham, Elizabeth A., Hayes, Ann G., Kilpatrick, Gavin J., Daas, Izaak Den, Large, Charles, Sheehan, Michael J., Stubbs, Carole M., Turpin, Michael P.
Published in Bioorganic & medicinal chemistry letters (02.02.1995)
Published in Bioorganic & medicinal chemistry letters (02.02.1995)
Get full text
Journal Article