Upregulation of Retinal Vascular Endothelial Growth Factor mRNAs in Spontaneously Diabetic Rats without Ophthalmoscopic Retinopathy
Segawa, Yasunori, Shirao, Yutaka, Yamagishi, Sho-ichi, Higashide, Tomomi, Kobayashi, Miho, Katsuno, Kenji, Iyobe, Akira, Harada, Hiromu, Sato, Fumiyasu, Miyata, Hiroshi, Asai, Hiroshi, Nishimura, Akira, Takahira, Masayuki, Souno, Tsutomu, Segawa, Youji, Maeda, Kazuhiko, Shima, Kenji, Mizuno, Akira, Yamamoto, Hiroshi, Kawasaki, Kazuo
Published in Ophthalmic research (01.11.1998)
Published in Ophthalmic research (01.11.1998)
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A practical synthesis of the [(2R)-3-(morpholinocarbonyl)-2-(1-naphthylmethyl)propionyl]-L-histidine moiety (P4-P2) in renin inhibitors
Harada, Hiromu, Yamaguchi, Toshiaki, Iyobe, Akira, Tsubaki, Atsushi, Kamijo, Tetsuhide, Iizuka, Kinji, Ogura, Katsuyuki, Kiso, Yoshiaki
Published in Journal of organic chemistry (01.03.1990)
Published in Journal of organic chemistry (01.03.1990)
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SUCCESSFUL ASYMMETRIC DIELS-ALDER APPROACH TO OPTICALLY ACTIVE C-NUCLEOSIDES. ENANTIOSELECTIVE TOTAL SYNTHESIS OF D-SHOWDOMYCIN AND D-2, 5-ANHYDROALLOSE DERIVATIVES
Takayama, Hiromitsu, Iyobe, Akira, Koizumi, Toru
Published in Chemical & pharmaceutical bulletin (01.01.1987)
Published in Chemical & pharmaceutical bulletin (01.01.1987)
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Synthesis and Structure-Activity Relationships of Human Renin Inhibitors Designed from Angiotensinogen Transition State
IIZUKA, Kinji, KAMIJO, Tetsuhide, HARADA, Hiromu, AKAHANE, Kenji, KUBOTA, Tetsuhiro, ETOH, Yasuo, SHIMAOKA, Iwao, TSUBAKI, Atsushi, MURAKAMI, Makoto, YAMAGUCHI, Toshiaki, IYOBE, Akira, UMEYAMA, Hideaki, KISO, Yoshiaki
Published in Chemical & pharmaceutical bulletin (01.01.1990)
Published in Chemical & pharmaceutical bulletin (01.01.1990)
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A practical synthesis of an orally potent renin inhibitor, isopropyl (2R,3S)-4-cyclohexyl-2-hydroxy-3-{N-[(2R)-2-morpholinocarbonylmethyl-3-(1-naphthyl)propionyl]-L-histidyl}aminobutyrate
HARADA, H, IYOBE, A, TSUBAKI, A, YAMAGUCHI, T, HIRATA, K, KAMIJO, T, IIZUKA, K, KISO, Y
Published in Journal of the Chemical Society, Perkin Transactions 1 (1990)
Published in Journal of the Chemical Society, Perkin Transactions 1 (1990)
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CRYSTALS OF GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVE
IYOBE, AKIRA, TATANI, KAZUYA, TERANISHI, HIROTAKA, YONEKUBO, SHIGERU, ISAJI, MASAYUKI
Year of Publication 02.10.2003
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Year of Publication 02.10.2003
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GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF
IYOBE, AKIRA, NISHIMURA, TOSHIHIRO, FUJIOKA, MINORU, HIRATOCHI, MASAHIRO, FUJIKURA, HIDEKI, KATSUNO, KENJI, ISAJI, MASAYUKI
Year of Publication 08.03.2001
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Year of Publication 08.03.2001
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Upregulation of retinal vascular endothelial growth factor mRNAs in spontaneously diabetic rats without ophthalmoscopic retinopathy. A possible participation of advanced glycation end products in the development of the early phase of diabetic retinopathy
Segawa, Y, Shirao, Y, Yamagishi, S, Higashide, T, Kobayashi, M, Katsuno, K, Iyobe, A, Harada, H, Sato, F, Miyata, H, Asai, H, Nishimura, A, Takahira, M, Souno, T, Segawa, Y, Maeda, K, Shima, K, Mizuno, A, Yamamoto, H, Kawasaki, K
Published in Ophthalmic research (01.11.1998)
Published in Ophthalmic research (01.11.1998)
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2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS
HARADA, HIROMU, NONAKA, YOSHINORI, IYOBE, AKIRA, FUJIKURA, HIDEKI, KAMATA, KOJI, KUSAMA, HIROSHI, HOTEI, YUKIHIKO, SATOH, FUMIYASU
Year of Publication 13.03.1997
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Year of Publication 13.03.1997
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2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS
HARADA, HIROMU, IYOBE, AKIRA, KOBAYASHI, MIHO, KAMATA, KOJI, KATSUNO, KENJI, KUSAMA, HIROSHI, SATOH, FUMIYASU, KOIZUMI, TAKASHI
Year of Publication 21.11.1996
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Year of Publication 21.11.1996
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CRYSTALS OF GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVE
YONEKUBO SHIGERU, ISAJI MASAYUKI, IYOBE AKIRA, TERANISHI HIROTAKA, TATANI KAZUYA
Year of Publication 29.02.2012
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Year of Publication 29.02.2012
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GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF
IYOBE, AKIRA, NISHIMURA, TOSHIHIRO, FUJIOKA, MINORU, HIRATOCHI, MASAHIRO, FUJIKURA, HIDEKI, KATSUNO, KENJI, ISAJI, MASAYUKI
Year of Publication 28.02.2014
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Year of Publication 28.02.2014
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Glukopyranosylbenzylbenzenderivatkrystaller
LSAJI MASAYUKI, YONEKUBO SHIGERU, IYOBE AKIRA, TERANISHI HIROTAKA, TATANI KAZUYA
Year of Publication 21.03.2011
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Year of Publication 21.03.2011
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CRYSTALS OF GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVE
IYOBE, AKIRA, TATANI, KAZUYA, TERANISHI, HIROTAKA, YONEKUBO, SHIGERU, ISAJI, MASAYUKI
Year of Publication 17.08.2010
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Year of Publication 17.08.2010
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CRYSTALS OF GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVE
IYOBE, AKIRA, TATANI, KAZUYA, TERANISHI, HIROTAKA, YONEKUBO, SHIGERU, ISAJI, MASAYUKI
Year of Publication 28.10.2009
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Year of Publication 28.10.2009
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Crystals of glucopyranosyloxybenzyl benzene derivative
SHIGERU YONEKUBO, AKIRA IYOBE, MASAYUKI ISAJI, KAZUYA TATANI, HIROTAKA TERANISHI
Year of Publication 12.03.2009
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Year of Publication 12.03.2009
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