An inhibitor of RORγ for chronic pulmonary obstructive disease treatment
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Published in Scientific reports (24.05.2022)
Published in Scientific reports (24.05.2022)
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Oxidative DMSO Cyclization Cascade to Bicyclic Hydroxyketonitriles
Kornfeind, John, Iyer, Pravin S, Keller, Taylor M, Fleming, Fraser F
Published in Journal of organic chemistry (06.05.2022)
Published in Journal of organic chemistry (06.05.2022)
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1,4-azaindole, a potential drug candidate for treatment of tuberculosis
Chatterji, Monalisa, Shandil, Radha, Manjunatha, M R, Solapure, Suresh, Ramachandran, Vasanthi, Kumar, Naveen, Saralaya, Ramanatha, Panduga, Vijender, Reddy, Jitendar, Prabhakar, K R, Sharma, Sreevalli, Sadler, Claire, Cooper, Christopher B, Mdluli, Khisi, Iyer, Pravin S, Narayanan, Shridhar, Shirude, Pravin S
Published in Antimicrobial agents and chemotherapy (01.09.2014)
Published in Antimicrobial agents and chemotherapy (01.09.2014)
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Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo
Shirude, Pravin S, Shandil, Radha, Sadler, Claire, Naik, Maruti, Hosagrahara, Vinayak, Hameed, Shahul, Shinde, Vikas, Bathula, Chandramohan, Humnabadkar, Vaishali, Kumar, Naveen, Reddy, Jitendar, Panduga, Vijender, Sharma, Sreevalli, Ambady, Anisha, Hegde, Naina, Whiteaker, James, McLaughlin, Robert E, Gardner, Humphrey, Madhavapeddi, Prashanti, Ramachandran, Vasanthi, Kaur, Parvinder, Narayan, Ashwini, Guptha, Supreeth, Awasthy, Disha, Narayan, Chandan, Mahadevaswamy, Jyothi, Vishwas, KG, Ahuja, Vijaykamal, Srivastava, Abhishek, Prabhakar, KR, Bharath, Sowmya, Kale, Ramesh, Ramaiah, Manjunatha, Choudhury, Nilanjana Roy, Sambandamurthy, Vasan K, Solapure, Suresh, Iyer, Pravin S, Narayanan, Shridhar, Chatterji, Monalisa
Published in Journal of medicinal chemistry (12.12.2013)
Published in Journal of medicinal chemistry (12.12.2013)
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Synthesis and in vitro evaluation of novel 8-aminoquinoline–pyrazolopyrimidine hybrids as potent antimalarial agents
Kannan, Murugan, Raichurkar, Anandkumar V., Khan, Fazlur Rahman Nawaz, Iyer, Pravin S.
Published in Bioorganic & medicinal chemistry letters (01.03.2015)
Published in Bioorganic & medicinal chemistry letters (01.03.2015)
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Development of potent and selective Cathepsin C inhibitors free of aortic binding liability by application of a conformational restriction strategy
Banerjee, Abhisek, Velagaleti, Ranganadh, Patil, Sandip, Pawar, Mahesh, Yadav, Pravin, Kadam, Pradip, Qadri, Mohammad Mohsin, Chakraborti, Samitabh, Saini, Jagmohan S., Behera, Dayanidhi B., Karanjai, Keya, Iyer, Pravin S., Gharat, Laxmikant A., Das, Sanjib
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
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4‑Aminoquinolone Piperidine Amides: Noncovalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity
Naik, Maruti, Humnabadkar, Vaishali, Tantry, Subramanyam J, Panda, Manoranjan, Narayan, Ashwini, Guptha, Supreeth, Panduga, Vijender, Manjrekar, Praveena, Jena, Lalit kumar, Koushik, Krishna, Shanbhag, Gajanan, Jatheendranath, Sandesh, Manjunatha, M. R, Gorai, Gopinath, Bathula, Chandramohan, Rudrapatna, Suresh, Achar, Vijayashree, Sharma, Sreevalli, Ambady, Anisha, Hegde, Naina, Mahadevaswamy, Jyothi, Kaur, Parvinder, Sambandamurthy, Vasan K, Awasthy, Disha, Narayan, Chandan, Ravishankar, Sudha, Madhavapeddi, Prashanti, Reddy, Jitendar, Prabhakar, KR, Saralaya, Ramanatha, Chatterji, Monalisa, Whiteaker, James, McLaughlin, Bob, Chiarelli, Laurent R, Riccardi, Giovanna, Pasca, Maria Rosalia, Binda, Claudia, Neres, João, Dhar, Neeraj, Signorino-Gelo, François, McKinney, John D, Ramachandran, Vasanthi, Shandil, Radha, Tommasi, Ruben, Iyer, Pravin S, Narayanan, Shridhar, Hosagrahara, Vinayak, Kavanagh, Stefan, Dinesh, Neela, Ghorpade, Sandeep R
Published in Journal of medicinal chemistry (26.06.2014)
Published in Journal of medicinal chemistry (26.06.2014)
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Lead Optimization of 1,4-Azaindoles as Antimycobacterial Agents
Shirude, Pravin S, Shandil, Radha K, Manjunatha, M. R, Sadler, Claire, Panda, Manoranjan, Panduga, Vijender, Reddy, Jitendar, Saralaya, Ramanatha, Nanduri, Robert, Ambady, Anisha, Ravishankar, Sudha, Sambandamurthy, Vasan K, Humnabadkar, Vaishali, Jena, Lalit K, Suresh, Rudrapatna S, Srivastava, Abhishek, Prabhakar, K. R, Whiteaker, James, McLaughlin, Robert E, Sharma, Sreevalli, Cooper, Christopher B, Mdluli, Khisi, Butler, Scott, Iyer, Pravin S, Narayanan, Shridhar, Chatterji, Monalisa
Published in Journal of medicinal chemistry (10.07.2014)
Published in Journal of medicinal chemistry (10.07.2014)
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Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity
R, Manjunatha M, Shandil, Radha, Panda, Manoranjan, Sadler, Claire, Ambady, Anisha, Panduga, Vijender, Kumar, Naveen, Mahadevaswamy, Jyothi, Sreenivasaiah, M, Narayan, Ashwini, Guptha, Supreeth, Sharma, Sreevalli, Sambandamurthy, Vasan K, Ramachandran, Vasanthi, Mallya, Meenakshi, Cooper, Christopher, Mdluli, Khisi, Butler, Scott, Tommasi, Ruben, Iyer, Pravin S, Narayanan, Shridhar, Chatterji, Monalisa, Shirude, Pravin S
Published in ACS medicinal chemistry letters (10.10.2019)
Published in ACS medicinal chemistry letters (10.10.2019)
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Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate
Hameed P, Shahul, Solapure, Suresh, Patil, Vikas, Henrich, Philipp P, Magistrado, Pamela A, Bharath, Sowmya, Murugan, Kannan, Viswanath, Pavithra, Puttur, Jayashree, Srivastava, Abhishek, Bellale, Eknath, Panduga, Vijender, Shanbag, Gajanan, Awasthy, Disha, Landge, Sudhir, Morayya, Sapna, Koushik, Krishna, Saralaya, Ramanatha, Raichurkar, Anandkumar, Rautela, Nikhil, Roy Choudhury, Nilanjana, Ambady, Anisha, Nandishaiah, Radha, Reddy, Jitendar, Prabhakar, K R, Menasinakai, Sreenivasaiah, Rudrapatna, Suresh, Chatterji, Monalisa, Jiménez-Díaz, María Belén, Martínez, María Santos, Sanz, Laura María, Coburn-Flynn, Olivia, Fidock, David A, Lukens, Amanda K, Wirth, Dyann F, Bandodkar, Balachandra, Mukherjee, Kakoli, McLaughlin, Robert E, Waterson, David, Rosenbrier-Ribeiro, Lyn, Hickling, Kevin, Balasubramanian, V, Warner, Peter, Hosagrahara, Vinayak, Dudley, Adam, Iyer, Pravin S, Narayanan, Shridhar, Kavanagh, Stefan, Sambandamurthy, Vasan K
Published in Nature communications (31.03.2015)
Published in Nature communications (31.03.2015)
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Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition
Safina, Brian S, Baker, Stewart, Baumgardner, Matt, Blaney, Paul M, Chan, Bryan K, Chen, Yung-Hsiang, Cartwright, Matthew W, Castanedo, Georgette, Chabot, Christine, Cheguillaume, Arnaud J, Goldsmith, Paul, Goldstein, David M, Goyal, Bindu, Hancox, Timothy, Handa, Raj K, Iyer, Pravin S, Kaur, Jasmit, Kondru, Rama, Kenny, Jane R, Krintel, Sussie L, Li, Jun, Lesnick, John, Lucas, Matthew C, Lewis, Cristina, Mukadam, Sophie, Murray, Jeremy, Nadin, Alan J, Nonomiya, Jim, Padilla, Fernando, Palmer, Wylie S, Pang, Jodie, Pegg, Neil, Price, Steve, Reif, Karin, Salphati, Laurent, Savy, Pascal A, Seward, Eileen M, Shuttleworth, Stephen, Sohal, Sukhjit, Sweeney, Zachary K, Tay, Suzanne, Tivitmahaisoon, Parcharee, Waszkowycz, Bohdan, Wei, Binqing, Yue, Qin, Zhang, Chenghong, Sutherlin, Daniel P
Published in Journal of medicinal chemistry (28.06.2012)
Published in Journal of medicinal chemistry (28.06.2012)
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N‑Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds
Ramachandran, Sreekanth, Hameed P, Shahul, Srivastava, Abhishek, Shanbhag, Gajanan, Morayya, Sapna, Rautela, Nikhil, Awasthy, Disha, Kavanagh, Stefan, Bharath, Sowmya, Reddy, Jitendar, Panduga, Vijender, Prabhakar, K. R, Saralaya, Ramanatha, Nanduri, Robert, Raichurkar, Anandkumar, Menasinakai, Sreenivasaiah, Achar, Vijayashree, Jiménez-Díaz, María Belén, Martínez, María Santos, Angulo-Barturen, Iñigo, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Duffy, Sandra, Avery, Vicky M, Waterson, David, Lee, Marcus C. S, Coburn-Flynn, Olivia, Fidock, David A, Iyer, Pravin S, Narayanan, Shridhar, Hosagrahara, Vinayak, Sambandamurthy, Vasan K
Published in Journal of medicinal chemistry (14.08.2014)
Published in Journal of medicinal chemistry (14.08.2014)
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Aminoazabenzimidazoles, a Novel Class of Orally Active Antimalarial Agents
Hameed P, Shahul, Chinnapattu, Murugan, Shanbag, Gajanan, Manjrekar, Praveena, Koushik, Krishna, Raichurkar, Anandkumar, Patil, Vikas, Jatheendranath, Sandesh, Rudrapatna, Suresh S, Barde, Shubhada P, Rautela, Nikhil, Awasthy, Disha, Morayya, Sapna, Narayan, Chandan, Kavanagh, Stefan, Saralaya, Ramanatha, Bharath, Sowmya, Viswanath, Pavithra, Mukherjee, Kakoli, Bandodkar, Balachandra, Srivastava, Abhishek, Panduga, Vijender, Reddy, Jitender, Prabhakar, K. R, Sinha, Achyut, Jiménez-Díaz, María Belén, Martínez, María Santos, Angulo-Barturen, Iñigo, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Duffy, Sandra, Avery, Vicky M, Magistrado, Pamela A, Lukens, Amanda K, Wirth, Dyann F, Waterson, David, Balasubramanian, V, Iyer, Pravin S, Narayanan, Shridhar, Hosagrahara, Vinayak, Sambandamurthy, Vasan K, Ramachandran, Sreekanth
Published in Journal of medicinal chemistry (10.07.2014)
Published in Journal of medicinal chemistry (10.07.2014)
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Reagent-Based DOS: Developing a Diastereoselective Methodology to Access Spirocyclic- and Fused Heterocyclic Ring Systems
Damerla, V. Surendra Babu, Tulluri, Chiranjeevi, Gundla, Rambabu, Naviri, Lava, Adepally, Uma, Iyer, Pravin S., Murthy, Y. L. N., Prabhakar, Nampally, Sen, Subhabrata
Published in Chemistry, an Asian journal (01.10.2012)
Published in Chemistry, an Asian journal (01.10.2012)
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Journal Article
2‑Phenylindole and Arylsulphonamide: Novel Scaffolds Bactericidal against Mycobacterium tuberculosis
Naik, Maruti, Ghorpade, Sandeep, Jena, Lalit Kumar, Gorai, Gopinath, Narayan, Ashwini, Guptha, Supreeth, Sharma, Sreevalli, Dinesh, Neela, Kaur, Parvinder, Nandishaiah, Radha, Bhat, Jyothi, Balakrishnan, Gayathri, Humnabadkar, Vaishali, Ramachandran, Vasanthi, Naviri, Lava Kumar, Khadtare, Pallavi, Panda, Manoranjan, Iyer, Pravin S, Chatterji, Monalisa
Published in ACS medicinal chemistry letters (11.09.2014)
Published in ACS medicinal chemistry letters (11.09.2014)
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Journal Article
2-Substituted N-aryl piperazines as novel triple reuptake inhibitors for the treatment of depression
Carter, David S., Cai, Hai-Ying, Lee, Eun Kyung, Iyer, Pravin S., Lucas, Matthew C., Roetz, Ralf, Schoenfeld, Ryan C., Weikert, Robert J.
Published in Bioorganic & medicinal chemistry letters (01.07.2010)
Published in Bioorganic & medicinal chemistry letters (01.07.2010)
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Journal Article
Synthesis of Privileged Scaffolds by Using Diversity-Oriented Synthesis
Surakanti, Ramu, Sanivarapu, Sumalatha, Thulluri, Chiranjeevi, Iyer, Pravin S., Tangirala, Raghuram S., Gundla, Rambabu, Addepally, Uma, Murthy, Y. L. N., Velide, Lakshmi, Sen, Subhabrata
Published in Chemistry, an Asian journal (01.06.2013)
Published in Chemistry, an Asian journal (01.06.2013)
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Journal Article
Corrigendum: Synthesis of Privileged Scaffolds by Using Diversity-Oriented Synthesis
Surakanti, Ramu, Sanivarapu, Sumalatha, Thulluri, Chiranjeevi, Iyer, Pravin S., Tangirala, Raghuram S., Gundla, Rambabu, Addepally, Uma, Murthy, Y. L. N., Velide, Lakshmi, Sen, Subhabrata
Published in Chemistry, an Asian journal (01.07.2014)
Published in Chemistry, an Asian journal (01.07.2014)
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