Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection
Hale, J. Scott, Youngblood, Ben, Latner, Donald R., Mohammed, Ata Ur Rasheed, Ye, Lilin, Akondy, Rama S., Wu, Tuoqi, Iyer, Smita S., Ahmed, Rafi
Published in Immunity (Cambridge, Mass.) (18.04.2013)
Published in Immunity (Cambridge, Mass.) (18.04.2013)
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Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol
Rahman, Khalidur, Desai, Chirayu, Iyer, Smita S, Thorn, Natalie E, Kumar, Pradeep, Liu, Yunshan, Smith, Tekla, Neish, Andrew S, Li, Hongliang, Tan, Shiyun, Wu, Pengbo, Liu, Xiaoxiong, Yu, Yuanjie, Farris, Alton B, Nusrat, Asma, Parkos, Charles A, Anania, Frank A
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2016)
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SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19
Beckman, Danielle, Bonillas, Alyssa, Diniz, Giovanne B., Ott, Sean, Roh, Jamin W., Elizaldi, Sonny R., Schmidt, Brian A., Sammak, Rebecca L., Van Rompay, Koen K.A., Iyer, Smita S., Morrison, John H.
Published in Cell reports (Cambridge) (01.11.2022)
Published in Cell reports (Cambridge) (01.11.2022)
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Induction of Th1-Biased T Follicular Helper (Tfh) Cells in Lymphoid Tissues during Chronic Simian Immunodeficiency Virus Infection Defines Functionally Distinct Germinal Center Tfh Cells
Velu, Vijayakumar, Mylvaganam, Geetha Hanna, Gangadhara, Sailaja, Hong, Jung Joo, Iyer, Smita S, Gumber, Sanjeev, Ibegbu, Chris C, Villinger, Francois, Amara, Rama Rao
Published in The Journal of immunology (1950) (01.09.2016)
Published in The Journal of immunology (1950) (01.09.2016)
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Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection
Penaloza-MacMaster, Pablo, Kamphorst, Alice O, Wieland, Andreas, Araki, Koichi, Iyer, Smita S, West, Erin E, O'Mara, Leigh, Yang, Shu, Konieczny, Bogumila T, Sharpe, Arlene H, Freeman, Gordon J, Rudensky, Alexander Y, Ahmed, Rafi
Published in The Journal of experimental medicine (25.08.2014)
Published in The Journal of experimental medicine (25.08.2014)
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SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques
Shaan Lakshmanappa, Yashavanth, Elizaldi, Sonny R, Roh, Jamin W, Schmidt, Brian A, Carroll, Timothy D, Weaver, Kourtney D, Smith, Justin C, Verma, Anil, Deere, Jesse D, Dutra, Joseph, Stone, Mars, Franz, Sergej, Sammak, Rebecca Lee, Olstad, Katherine J, Rachel Reader, J, Ma, Zhong-Min, Nguyen, Nancy K, Watanabe, Jennifer, Usachenko, Jodie, Immareddy, Ramya, Yee, JoAnn L, Weiskopf, Daniela, Sette, Alessandro, Hartigan-O'Connor, Dennis, McSorley, Stephen J, Morrison, John H, Tran, Nam K, Simmons, Graham, Busch, Michael P, Kozlowski, Pamela A, Van Rompay, Koen K A, Miller, Christopher J, Iyer, Smita S
Published in Nature communications (22.01.2021)
Published in Nature communications (22.01.2021)
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Blocking integrin α4β7-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis
Rai, Ravi P., Liu, Yunshan, Iyer, Smita S., Liu, Silvia, Gupta, Biki, Desai, Chirayu, Kumar, Pradeep, Smith, Tekla, Singhi, Aatur D., Nusrat, Asma, Parkos, Charles A., Monga, Satdarshan P., Czaja, Mark J., Anania, Frank A., Raeman, Reben
Published in Journal of hepatology (01.11.2020)
Published in Journal of hepatology (01.11.2020)
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Characteristics of HIV target CD4 T cells collected using different sampling methods from the genital tract of HIV seronegative women
Iyer, Smita S, Sabula, Michael J, Mehta, C Christina, Haddad, Lisa B, Brown, Nakita L, Amara, Rama R, Ofotokun, Igho, Sheth, Anandi N
Published in PloS one (01.06.2017)
Published in PloS one (01.06.2017)
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Deep analysis of CD4 T cells in the rhesus CNS during SIV infection
Elizaldi, Sonny R, Verma, Anil, Ma, Zhong-Min, Ott, Sean, Rajasundaram, Dhivyaa, Hawes, Chase E, Lakshmanappa, Yashavanth Shaan, Cottrell, Mackenzie L, Kashuba, Angela D M, Ambrose, Zandrea, Lifson, Jeffrey D, Morrison, John H, Iyer, Smita S
Published in PLoS pathogens (07.12.2023)
Published in PLoS pathogens (07.12.2023)
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Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques
Van Rompay, Koen K A, Olstad, Katherine J, Sammak, Rebecca L, Dutra, Joseph, Watanabe, Jennifer K, Usachenko, Jodie L, Immareddy, Ramya, Verma, Anil, Shaan Lakshmanappa, Yashavanth, Schmidt, Brian A, Roh, Jamin W, Elizaldi, Sonny R, Allen, A Mark, Muecksch, Frauke, Lorenzi, Julio C C, Lockwood, Sarah, Pollard, Rachel E, Yee, JoAnn L, Nham, Peter B, Ardeshir, Amir, Deere, Jesse D, Patterson, Jean, Dang, Que, Hatziioannou, Theodora, Bieniasz, Paul D, Iyer, Smita S, Hartigan-O'Connor, Dennis J, Nussenzweig, Michel C, Reader, J Rachel
Published in PLoS pathogens (06.07.2021)
Published in PLoS pathogens (06.07.2021)
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Chronic SIV-Induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain
Elizaldi, Sonny R, Hawes, Chase E, Verma, Anil, Shaan Lakshmanappa, Yashavanth, Dinasarapu, Ashok R, Schlegel, Brent T, Rajasundaram, Dhivyaa, Li, Jie, Durbin-Johnson, Blythe P, Ma, Zhong-Min, Pal, Pabitra B, Beckman, Danielle, Ott, Sean, Raeman, Reben, Lifson, Jeffrey, Morrison, John H, Iyer, Smita S
Published in The Journal of clinical investigation (01.05.2024)
Published in The Journal of clinical investigation (01.05.2024)
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Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques
Iyer, Smita S, Gangadhara, Sailaja, Victor, Blandine, Gomez, Rosy, Basu, Rahul, Hong, Jung Joo, Labranche, Celia, Montefiori, David C, Villinger, Francois, Moss, Bernard, Amara, Rama Rao
Published in The Journal of immunology (1950) (01.08.2015)
Published in The Journal of immunology (1950) (01.08.2015)
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Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection
Hawes, Chase E, Elizaldi, Sonny R, Beckman, Danielle, Diniz, Giovanne B, Shaan Lakshmanappa, Yashavanth, Ott, Sean, Durbin-Johnson, Blythe P, Dinasarapu, Ashok R, Gompers, Andrea, Morrison, John H, Iyer, Smita S
Published in Journal of neuroinflammation (06.10.2022)
Published in Journal of neuroinflammation (06.10.2022)
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Tailoring Tfh profiles enhances antibody persistence to a clade C HIV-1 vaccine in rhesus macaques
Verma, Anil, Hawes, Chase E, Elizaldi, Sonny R, Smith, Justin C, Rajasundaram, Dhivyaa, Pedersen, Gabriel Kristian, Shen, Xiaoying, Williams, LaTonya D, Tomaras, Georgia D, Kozlowski, Pamela A, Amara, Rama R, Iyer, Smita S
Published in eLife (22.02.2024)
Published in eLife (22.02.2024)
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Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
Verma, Anil, Schmidt, Brian A, Elizaldi, Sonny R, Nguyen, Nancy K, Walter, Korey A, Beck, Zoltan, Trinh, Hung V, Dinasarapu, Ashok R, Lakshmanappa, Yashavanth Shaan, Rane, Niharika N, Matyas, Gary R, Rao, Mangala, Shen, Xiaoying, Tomaras, Georgia D, LaBranche, Celia C, Reimann, Keith A, Foehl, David H, Gach, Johannes S, thal, Donald N, Kozlowski, Pamela A, Amara, Rama R, Iyer, Smita S
Published in Journal of virology (28.02.2020)
Published in Journal of virology (28.02.2020)
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Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice
Xu, Jianguo, Woods, Charles R, Mora, Ana L, Joodi, Robert, Brigham, Kenneth L, Iyer, Smita, Rojas, Mauricio
Published in American journal of physiology. Lung cellular and molecular physiology (01.07.2007)
Published in American journal of physiology. Lung cellular and molecular physiology (01.07.2007)
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Cysteine Redox Potential Determines Pro-Inflammatory IL-1β Levels
Iyer, Smita S., Accardi, Carolyn J., Ziegler, Thomas R., Blanco, Roberto A., Ritzenthaler, Jeffrey D., Rojas, Mauricio, Roman, Jesse, Jones, Dean P.
Published in PloS one (27.03.2009)
Published in PloS one (27.03.2009)
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