P4‐188: ORL1: A Novel Mechanism with Potential to Provide Beneficial Effects for Depressive Symptoms Associated With Alzheimer's Disease (AD)
Iyer, Rathna, Duplantier, Allen, Brodney, Michael, Snyder, Bradley, Arnold, Elizabeth, McDowell, Laura, Leurent, Claire, Prior, Faith, Zagouras, Panayiotis, Roof, Robin
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
ORL1: A Novel Mechanism With Potential to Provide Beneficial Effects for Depressive Symptoms Associated With Alzheimer's Disease (AD)
Iyer, Rathna, Duplantier, Allen, Brodney, Michael, Snyder, Bradley, Arnold, Elizabeth, McDowell, Laura, Leurent, Claire, Prior, Faith, Zagouras, Panayiotis, Roof, Robin
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
P1‐296: Gamma‐secretase inhibitors and gamma‐secretase modulators differentially regulate amyloid‐beta 42 peptide generation in native brain membrane preparations from multiple species
Oborski, Christine E.J., Parker, Christine, Pettersson, Martin, Johnson, Douglas S., Iyer, Rathna, Bales, Kelly
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
Gamma-secretase inhibitors and gamma-secretase modulators differentially regulate amyloid-beta 42 peptide generation in native brain membrane preparations from multiple species
Oborski, Christine E.J, Parker, Christine, Pettersson, Martin, Johnson, Douglas S, Iyer, Rathna, Bales, Kelly
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
Design, synthesis, and pharmacological evaluation of phenoxy pyridyl derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists
DOUNAY, Amy B, BARTA, Nancy S, MAITI, Samarendra N, ORTWINE, Daniel F, PROBERT, Al, STRATMAN, Nancy C, SUBEDI, Rajendra, WHISMAN, Tammy, WENJIAN XU, ZOSKI, Kim, CAMPBELL, Brian M, COLEMAN, Corey, COLLANTES, Elizabeth M, DENNY, Lynne, DUTTA, Satavisha, GRAY, David L, DONGFENG HOU, IYER, Rathna
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Journal Article
P4‐184: Profile of selective ORL1 antagonist demonstrates mechanism safe to target for symptomatic treatment in Alzheimer's Disease
Duplantier, Allen, Iyer, Rathna, Pettersen, Betty, Roof, Robin, Cianfrogna, Julie, Leung, Louis, Brodney, Michael, McDowell, Laura, Barricklow, Jason, Cannon, Keri, Chang, Cheng, Leurent, Claire, Prior, Faith, Taylor, Christine, Wisialowski, Todd
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Profile of selective ORL1 antagonist demonstrates mechanism safe to target for symptomatic treatment in Alzheimer's Disease
Duplantier, Allen, Iyer, Rathna, Pettersen, Betty, Roof, Robin, Cianfrogna, Julie, Leung, Louis, Brodney, Michael, McDowell, Laura, Barricklow, Jason, Cannon, Keri, Chang, Cheng, Leurent, Claire, Prior, Faith, Taylor, Christine, Wisialowski, Todd
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
P4‐197: A selective ORL1 antagonist enhances hippocampal function and reverses pharmacologically induced cognitive deficits in rodents
Roof, Robin, Siok, Chester, Hajos, Mihaly, Cianfrogna, Julie, Chang, Cheng, Leung, Louis, Duplantier, Allen, Brodney, Michael, McDowell, Laura, Prior, Faith, Vanase‐Frawley, Michelle, McGinnis, Dina, Kozak, Rouba, Seymour, Patricia, Leurent, Claire, Iyer, Rathna
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
A selective ORL1 antagonist enhances hippocampal function and reverses pharmacologically induced cognitive deficits in rodents
Roof, Robin, Siok, Chester, Hajos, Mihaly, Cianfrogna, Julie, Chang, Cheng, Leung, Louis, Duplantier, Allen, Brodney, Michael, McDowell, Laura, Prior, Faith, Vanase-Frawley, Michelle, McGinnis, Dina, Kozak, Rouba, Seymour, Patricia, Leurent, Claire, Iyer, Rathna
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Design, synthesis, and pharmacological evaluation of phenoxy pyridyl derivatives as dual norepinephrine reuptake inhibitors and 5-HT sub(1A) partial agonists
Dounay, Amy B, Barta, Nancy S, Campbell, Brian M, Coleman, Corey, Collantes, Elizabeth M, Denny, Lynne, Dutta, Satavisha, Gray, David L, Hou, Dongfeng, Iyer, Rathna, Maiti, Samarendra N, Ortwine, Daniel F, Probert, Al, Stratman, Nancy C, Subedi, Rajendra, Whisman, Tammy, Xu, Wenjian, Zoski, Kim
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Journal Article
Design, synthesis, and pharmacological evaluation of phenoxy pyridyl derivatives as dual norepinephrine reuptake inhibitors and 5-HT 1A partial agonists
Dounay, Amy B., Barta, Nancy S., Campbell, Brian M., Coleman, Corey, Collantes, Elizabeth M., Denny, Lynne, Dutta, Satavisha, Gray, David L., Hou, Dongfeng, Iyer, Rathna, Maiti, Samarendra N., Ortwine, Daniel F., Probert, Al, Stratman, Nancy C., Subedi, Rajendra, Whisman, Tammy, Xu, Wenjian, Zoski, Kim
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article