Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
Zhang, Yueping, Han, Yong-Hae, Putluru, Siva Prasad, Matta, Murali Krishna, Kole, Prashant, Mandlekar, Sandhya, Furlong, Michael T, Liu, Tongtong, Iyer, Ramaswamy A, Marathe, Punit, Yang, Zheng, Lai, Yurong, Rodrigues, A David
Published in Drug metabolism and disposition (01.03.2016)
Published in Drug metabolism and disposition (01.03.2016)
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Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
Kraynov, Eugenia, Kamath, Amrita V, Walles, Markus, Tarcsa, Edit, Deslandes, Antoine, Iyer, Ramaswamy A, Datta-Mannan, Amita, Sriraman, Priya, Bairlein, Michaela, Yang, Johnny J, Barfield, Matthew, Xiao, Guangqing, Escandon, Enrique, Wang, Weirong, Rock, Dan A, Chemuturi, Nagendra V, Moore, David J
Published in Drug metabolism and disposition (01.05.2016)
Published in Drug metabolism and disposition (01.05.2016)
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Cysteine conjugate β-lyase-dependent metabolism of compound A (2-[fluoromethoxy]-1,1,3,3,3-pentafluoro-1-propene) in Human subjects anesthetized with Sevoflurane and in rats given compound A
IYER, R. A, FRINK, E. JR, EBERT, T. J, ANDERS, M. W
Published in Anesthesiology (Philadelphia) (01.03.1998)
Published in Anesthesiology (Philadelphia) (01.03.1998)
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Oral bioavailability and disposition of [14C]omapatrilat in healthy subjects
Malhotra, B K, Iyer, R A, Soucek, K M, Behr, D, Liao, W C, Mitroka, J G, Kaul, S, Cohen, M B, Knupp, C A
Published in Journal of clinical pharmacology (01.08.2001)
Published in Journal of clinical pharmacology (01.08.2001)
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Heterocyclic N-Acetoxyarylamines, Models for the Putative Ultimate Carcinogens of Aromatic Amines: 2-Acetoxyamino-5-phenylpyridine and 2-Acetoxyaminopyridine
Ojala, W. H., Iyer, R. A., Hanna, P. E., Gleason, W. B.
Published in Acta crystallographica. Section C, Crystal structure communications (15.05.1997)
Published in Acta crystallographica. Section C, Crystal structure communications (15.05.1997)
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Nephrotoxicity of the glutathione and cysteine S-conjugates of the sevoflurane degradation product 2-(fluoromethoxy)-1,1,3,3, 3-pentafluoro-1-propene (Compound A) in male Fischer 344 rats
Iyer, R A, Baggs, R B, Anders, M W
Published in The Journal of pharmacology and experimental therapeutics (01.12.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.12.1997)
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Metabolism of [14C]Omapatrilat, a Sulfhydryl-Containing Vasopeptidase Inhibitor in Humans
Ramaswamy A. Iyer, James Mitroka, Bimal Malhotra, Samuel Bonacorsi, Jr, Stephen C. Waller, J. Kent Rinehart, Vikram A. Roongta, Kishin Kripalani
Published in Drug metabolism and disposition (01.01.2001)
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Published in Drug metabolism and disposition (01.01.2001)
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Mass balance, pharmacokinetics, and metabolism of [ 14 C] brivanib (BMS-582664), prodrug of BMS-540215, in subjects with advanced or metastatic solid tumors
Ganapathi, R., Mekhail, T., Wu, C., Fischer, B., Gong, J., Iyer, R. A., Gan, J., Pursley, J., Patricia, D., Masson, E.
Published in Journal of clinical oncology (20.05.2009)
Published in Journal of clinical oncology (20.05.2009)
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Comparative Biotransformation of Radiolabeled [14C]Omapatrilat and Stable-labeled [13C2]Omapatrilat after Oral Administration to Rats, Dogs, and Humans
Ramaswamy A. Iyer, Bimal Malhotra, Sanaullah Khan, James Mitroka, Samuel Bonacorsi, Jr, Stephen C. Waller, J. Kent Rinehart, Kishin Kripalani
Published in Drug metabolism and disposition (01.01.2003)
Published in Drug metabolism and disposition (01.01.2003)
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N-(carbobenzyloxy)isatin: A slow binding α-keto lactam inhibitor of α-chymotrypsin
Iyer, Ramaswamy A., Hanna, Patrick E.
Published in Bioorganic & medicinal chemistry letters (05.01.1995)
Published in Bioorganic & medicinal chemistry letters (05.01.1995)
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Fourier-transform ion cyclotron resonance mass spectrometric studies of elimination reactions of anionic bases with metabolites of a fluorinated anesthetic agent: towards modeling bioactivation in the gas phase
Luu, Nganha C, Iyer, Ramaswamy A, Anders, M.W, Ridge, Douglas P
Published in International journal of mass spectrometry (21.01.2000)
Published in International journal of mass spectrometry (21.01.2000)
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