Synthesis and structure–activity analysis of diphenylpyrazolodiazene inhibitors of the HIV-1 Nef virulence factor
Iyer, Prema C., Zhao, Jielu, Emert-Sedlak, Lori A., Moore, Kerry K., Smithgall, Thomas E., Day, Billy W.
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
Get full text
Journal Article
Design and activity of AP endonuclease-1 inhibitors
Feng, Zhiwei, Kochanek, Stanton, Close, David, Wang, LiRong, Srinivasan, Ajay, Almehizia, Abdulrahman A., Iyer, Prema, Xie, Xiang-Qun, Johnston, Paul A., Gold, Barry
Published in Journal of chemical biology (01.07.2015)
Published in Journal of chemical biology (01.07.2015)
Get full text
Journal Article
Synthesis and Characterization of DNA Minor Groove Binding Alkylating Agents
Iyer, Prema, Srinivasan, Ajay, Singh, Sreelekha K, Mascara, Gerard P, Zayitova, Sevara, Sidone, Brian, Fouquerel, Elise, Svilar, David, Sobol, Robert W, Bobola, Michael S, Silber, John R, Gold, Barry
Published in Chemical research in toxicology (18.01.2013)
Published in Chemical research in toxicology (18.01.2013)
Get full text
Journal Article
Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism
Huang, Qingqiu, Stalnecker, Clint, Zhang, Chengliang, McDermott, Lee A., Iyer, Prema, O’Neill, Jason, Reimer, Shawn, Cerione, Richard A., Katt, William P.
Published in The Journal of biological chemistry (09.03.2018)
Published in The Journal of biological chemistry (09.03.2018)
Get full text
Journal Article
Pharmacological Validation of HDAC8 as a Therapeutic Target for AKI: PO0331
Huryn, Donna M., Long, Keith E., McDaniels, Michael D., Delgado, Rachel, Vaughn, Zoe, Iyer, Prema C., Sander, Veronika, Davidson, Alan J., de Caestecker, Mark P., Hukriede, Neil A.
Published in Journal of the American Society of Nephrology (01.10.2021)
Published in Journal of the American Society of Nephrology (01.10.2021)
Get full text
Journal Article
GAC inhibitors with a 4-hydroxypiperidine spacer: Requirements for potency
McDermott, Lee, Koes, David, Mohammed, Shabber, Iyer, Prema, Boby, Melissa, Balasubramanian, Venkatakrishnan, Geedy, Mackenzie, Katt, William, Cerione, Richard
Published in Bioorganic & medicinal chemistry letters (01.10.2019)
Published in Bioorganic & medicinal chemistry letters (01.10.2019)
Get full text
Journal Article
Design and evaluation of novel glutaminase inhibitors
McDermott, Lee A., Iyer, Prema, Vernetti, Larry, Rimer, Shawn, Sun, Jingran, Boby, Melissa, Yang, Tianyi, Fioravanti, Michael, O’Neill, Jason, Wang, Liwei, Drakes, Dylan, Katt, William, Huang, Qingqiu, Cerione, Richard
Published in Bioorganic & medicinal chemistry (15.04.2016)
Published in Bioorganic & medicinal chemistry (15.04.2016)
Get full text
Journal Article
Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology
Pei, Fen, Li, Hongchun, Henderson, Mark J., Titus, Steven A., Jadhav, Ajit, Simeonov, Anton, Cobanoglu, Murat Can, Mousavi, Seyed H., Shun, Tongying, McDermott, Lee, Iyer, Prema, Fioravanti, Michael, Carlisle, Diane, Friedlander, Robert M., Bahar, Ivet, Taylor, D. Lansing, Lezon, Timothy R., Stern, Andrew M., Schurdak, Mark E.
Published in Scientific reports (19.12.2017)
Published in Scientific reports (19.12.2017)
Get full text
Journal Article
XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine
Russo, Debora, Fronza, Gilberto, Ottaggio, Laura, Monti, Paola, Perfumo, Chiara, Inga, Alberto, Iyer, Prema, Gold, Barry, Menichini, Paola
Published in DNA repair (01.07.2010)
Published in DNA repair (01.07.2010)
Get full text
Journal Article
HDAC INHIBITORS
Kristufek, Tyler, Huryn, Donna M, Panda, Jagannath, Terrab, Leila, Sozer, Uygar, Liang, Mary, Chauhan, Shikha Singh, Crocker, Desirae Lynn, Wipf, Peter, Joyasawal, Sipak, Topacio, Andrea, Thornton, Alyssa, LaPorte, Matthew G, Houghton, Michael James, Iyer, Prema, Maskrey, Taber Sarah
Year of Publication 15.02.2024
Get full text
Year of Publication 15.02.2024
Patent