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The CNS-Penetrant Soluble Guanylate Cyclase Stimulator CY6463 Reveals its Therapeutic Potential in Neurodegenerative Diseases
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Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator
Rennie, Glen R., Barden, Timothy C., Bernier, Sylvie G., Carvalho, Andrew, Deming, Renee, Germano, Peter, Hudson, Colleen, Im, G-Yoon J., Iyengar, Rajesh R., Jia, Lei, Jung, Joon, Kim, Elise, Lee, Thomas W.-H., Mermerian, Ara, Moore, Joel, Nakai, Takashi, Perl, Nicholas R., Tobin, Jenny, Zimmer, Daniel P., Renhowe, Paul A.
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Year of Publication 21.05.2024
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Year of Publication 03.05.2024
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Year of Publication 25.08.2023
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Year of Publication 25.08.2023
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An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists
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Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
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Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity
Judd, Andrew S., Souers, Andrew J., Wodka, Dariusz, Zhao, Gang, Mulhern, Mathew M., Iyengar, Rajesh R., Gao, Ju, Lynch, John K., Freeman, Jennifer C., Falls, H. Douglas, Brodjian, Sevan, Dayton, Brian D., Reilly, Regina M., Gintant, Gary, Limberis, James T., Mikhail, Ann, Leitza, Sandra T., Houseman, Kathryn A., Diaz, Gilbert, Bush, Eugene N., Shapiro, Robin, Knourek-Segel, Victoria, Hernandez, Lisa E., Marsh, Kennan C., Sham, Hing L., Collins, Christine A., Kym, Philip R.
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SHEPPECK JAMES EDWARD, MERMERIAN ARA, IYENGAR RAJESH R, NAKAI TAKASHI, BARDEN TIMOTHY CLAUDE, RENNIE GLEN ROBERT, RENHOWE PAUL ALLAN
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Year of Publication 12.08.2019
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Year of Publication 12.08.2019
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LONG KIMBERLY KAFADAR, RENHOWE PAUL ALLEN, HUDSON COLLEEN, JUNG JOON, BARDEM TIMOTHY CLAUDE, MARK G. CURRIE, IYER KARTHIK, MERMERIAN ARA, PERL NICHOLAS ROBERT, IM G YOON JAMIE, NAKAI TAKASHI, RENNIE GLEN ROBERT, JIA JAMES, SHEPPECK JAMES EDWARD, MOORE JOEL, LEE THOMAS WAI HO, IYENGAR RAJESH R, YU XIANG Y, MILNE GEORGE TODD
Year of Publication 23.02.2021
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Year of Publication 23.02.2021
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Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: The effects of chirality on substituted indan-1-ylamines
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Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
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JUNG JOON, IYER KARTHIK, TANG KIM, MERMERIAN ARA, IM G YOON JAMIE, NAKAI TAKASHI, RENNIE GLEN ROBERT, JIA LEI, GERMANO PETER, LEE THOMAS WAI HO, IYENGAR RAJESH R, BARDEN TIMOTHY CLAUDE, RENHOWE PAUL ALLAN
Year of Publication 25.04.2019
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Year of Publication 25.04.2019
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Year of Publication 14.11.2013
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Year of Publication 14.11.2013
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LONG KIMBERLY KAFADAR, RENHOWE PAUL ALLEN, HUDSON COLLEEN, JUNG JOON, IYER KARTHIK, MERMERIAN ARA, PERL NICHOLAS ROBERT, IM G YOON JAMIE, NAKAI TAKASHI, RENNIE GLEN ROBERT, JIA JAMES, SHEPPECK JAMES EDWARD, MOORE JOEL, LEE THOMAS WAI HO, IYENGAR RAJESH R, YU XIANG Y, MILNE GEORGE TODD, BARDEN TIMOTHY CLAUDE
Year of Publication 18.11.2015
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Year of Publication 18.11.2015
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Discovery of IWP-051, a Novel Orally Bioavailable Soluble Guanylate Cyclase Stimulator with Sustained and Dose-Dependent Hemodynamic Effects
Nakai, Takashi, Perl, Nicholas R, Iyengar, Rajesh R, Mermerian, Ara, Im, G-Yoon J, Lee, Thomas W-H, Rennie, Glen R, Jia, James, Renhowe, Paul A, Barden, Timothy C, Sheppeck, James E, Iyer, Karthik, Jung, Joon, Milne, G Todd, Segal, Chrissie, Long, Kimberly, Miyashiro, Joy, Bernier, Sylvie, Jacobson, Sarah, Tobin, Jenny, Shea, Courtney, Germano, Peter, Chien, Yueh-tyng, Zimmer, Daniel
Published in BMC pharmacology & toxicology (02.09.2015)
Published in BMC pharmacology & toxicology (02.09.2015)
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