Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models
Okamoto, Kiyoshi, Kodama, Kotaro, Takase, Kazuma, Sugi, Naoko Hata, Yamamoto, Yuji, Iwata, Masao, Tsuruoka, Akihiko
Published in Cancer letters (28.10.2013)
Published in Cancer letters (28.10.2013)
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Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models
Funahashi, Yasuhiro, Iwata, Masao, Okamoto, Kiyoshi, Kimura, Takayuki, Hata-Sugi, Naoko, Kodama, Kotaro, Matsui, Junji, Tohyama, Osamu, Minoshima, Yukinori
Published in Journal of Thyroid Research (01.01.2014)
Published in Journal of Thyroid Research (01.01.2014)
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Splicing factor SF3b as a target of the antitumor natural product pladienolide
Mizui, Yoshiharu, Kotake, Yoshihiko, Sagane, Koji, Owa, Takashi, Mimori-Kiyosue, Yuko, Shimizu, Hajime, Uesugi, Mai, Ishihama, Yasushi, Iwata, Masao
Published in Nature chemical biology (01.09.2007)
Published in Nature chemical biology (01.09.2007)
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Radiolabeled liposome imaging determines an indication for liposomal anticancer agent in ovarian cancer mouse xenograft models
Ito, Ken, Hamamichi, Shusei, Asano, Makoto, Hori, Yusaku, Matsui, Junji, Iwata, Masao, Funahashi, Yasuhiro, Umeda, Izumi O., Fujii, Hirofumi
Published in Cancer science (01.01.2016)
Published in Cancer science (01.01.2016)
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High antitumor activity of pladienolide B and its derivative in gastric cancer
Sato, Momoko, Muguruma, Naoki, Nakagawa, Tadahiko, Okamoto, Koichi, Kimura, Tetsuo, Kitamura, Shinji, Yano, Hiromi, Sannomiya, Katsutaka, Goji, Takahiro, Miyamoto, Hiroshi, Okahisa, Toshiya, Mikasa, Hiroaki, Wada, Satoshi, Iwata, Masao, Takayama, Tetsuji
Published in Cancer science (01.01.2014)
Published in Cancer science (01.01.2014)
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E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models
Watanabe Miyano, Saori, Yamamoto, Yuji, Kodama, Kotaro, Miyajima, Yukiko, Mikamoto, Masaki, Nakagawa, Takayuki, Kuramochi, Hiroko, Funasaka, Setsuo, Nagao, Satoshi, Sugi, Naoko Hata, Okamoto, Kiyoshi, Minoshima, Yukinori, Nakatani, Yusuke, Karoji, Yuki, Ohashi, Isao, Yamane, Yoshinobu, Okada, Toshimi, Matsushima, Tomohiro, Matsui, Junji, Iwata, Masao, Uenaka, Toshimitsu, Tsuruoka, Akihiko
Published in Molecular cancer therapeutics (01.11.2016)
Published in Molecular cancer therapeutics (01.11.2016)
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Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107: III. In Vitro and In Vivo Antitumor Activities
MIZUI, YOSHIHARU, SAKAI, TAKASHI, IWATA, MASAO, UENAKA, TOSHIMITSU, OKAMOTO, KIYOSHI, SHIMIZU, HAJIME, YAMORI, TAKAO, YOSHIMATSU, KENTARO, ASADA, MAKOTO
Published in Journal of antibiotics (01.03.2004)
Published in Journal of antibiotics (01.03.2004)
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Biological validation that SF3b is a target of the antitumor macrolide pladienolide
Yokoi, Akira, Kotake, Yoshihiko, Takahashi, Kentaro, Kadowaki, Tadashi, Matsumoto, Yoshiko, Minoshima, Yukinori, Sugi, Naoko H., Sagane, Koji, Hamaguchi, Makoto, Iwata, Masao, Mizui, Yoshiharu
Published in The FEBS journal (01.12.2011)
Published in The FEBS journal (01.12.2011)
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E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
Yamada, Kazuhiko, Hori, Yusaku, Inoue, Satoshi, Yamamoto, Yuji, Iso, Kentaro, Kamiyama, Hiroshi, Yamaguchi, Atsumi, Kimura, Takayuki, Uesugi, Mai, Ito, Junichi, Matsuki, Masahiro, Nakamoto, Kazutaka, Harada, Hitoshi, Yoneda, Naoki, Takemura, Atsushi, Kushida, Ikuo, Wakayama, Naomi, Kubara, Kenji, Kato, Yu, Semba, Taro, Yokoi, Akira, Matsukura, Masayuki, Odagami, Takenao, Iwata, Masao, Tsuruoka, Akihiko, Uenaka, Toshimitsu, Matsui, Junji, Matsushima, Tomohiro, Nomoto, Kenichi, Kouji, Hiroyuki, Owa, Takashi, Funahashi, Yasuhiro, Ozawa, Yoichi
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Abstract 3778: In vitro and in vivo characterization of E7090, a novel and selective FGFR inhibitor, for the treatment of endometrial cancer
Miyano, Saori Watanabe, Yamamoto, Yuji, Kodama, Kotaro, Sugi, Naoko Hata, Minoshima, Yukinori, Matsui, Junji, Iwata, Masao
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Novel ATP-competitive MEK inhibitor E6201 is effective against vemurafenib-resistant melanoma harboring the MEK1-C121S mutation in a preclinical model
Narita, Yusuke, Okamoto, Kiyoshi, Kawada, Megumi Ikemori, Takase, Kazuma, Minoshima, Yukinori, Kodama, Kotaro, Iwata, Masao, Miyamoto, Norimasa, Sawada, Kohei
Published in Molecular cancer therapeutics (01.04.2014)
Published in Molecular cancer therapeutics (01.04.2014)
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