Structure-activity relationship (SBR) studies on oxazolidinone antibacterial agents. 2. Relationship between lipophilicity and antibacterial activity in 5-thiocarbonyl oxazolidinones
Tokuyama, R, Takahashi, Y, Tomita, Y, Tsubouchi, M, Yoshida, T, Iwasaki, N, Kado, N, Okezaki, E, Nagata, O
Published in Chemical & pharmaceutical bulletin (2001)
Published in Chemical & pharmaceutical bulletin (2001)
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Structure-Activity Relationship (SAR) Studies on Oxazolidinone Antibacterial Agents. 1. Conversion of 5-Substituent on Oxazolidinone
TOKUYAMA, Ryukou, TAKAHASHI, Yoshiei, TOMITA, Yayoi, SUZUKI, Tomio, YOSHIDA, Toshihiko, IWASAKI, Nobuhiko, KADO, Noriyuki, OKEZAKI, Eiichi, NAGATA, Osamu
Published in Chemical & pharmaceutical bulletin (2001)
Published in Chemical & pharmaceutical bulletin (2001)
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Structure-activity relationship (SAR) studies on oxazolidinone antibacterial agents. 3. Synthesis and evaluation of 5-thiocarbamate oxazolidinones
Tokuyama, R, Takahashi, Y, Tomita, Y, Tsubouchi, M, Iwasaki, N, Kado, N, Okezaki, E, Nagata, O
Published in Chemical & pharmaceutical bulletin (2001)
Published in Chemical & pharmaceutical bulletin (2001)
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Synthesis and Gastrointestinal Prokinetic Activity of Novel Benzamide Derivatives with Amphoteric Side Chains
SAKAGUCHI, Jun, IWASAKI, Nobuhiko, IWANAGA, Yuji, SAITO, Takaharu, TAKAHARA, Eiji, KATO, Hideo, HANAOKA, Miyoji
Published in Chemical & pharmaceutical bulletin (01.04.2001)
Published in Chemical & pharmaceutical bulletin (01.04.2001)
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Effects of alkyl substitutions of xanthine skeleton on bronchodilation
Sakai, Ryosuke, Konno, Kayo, Yamamoto, Yasunori, Sanae, Fujiko, Takagi, Kenzo, Hasegawa, Takaaki, Iwasaki, Nobuhiko, Kakiuchi, Masato, Kato, Hideo, Miyamoto, Kenichi
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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An Improved Synthesis of Butyl 4-[(4-Amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate (AU-224)
SAKAGUCHI, Jun, HIGASHI, Taijiro, AZUMA, Takahiro, SUZUKI, Tomio, IWASAKI, Nobuhiko, KONDO, Noriyuki, NAGATA, Osamu, KATO, Hideo, HANAOKA, Miyoji
Published in Chemical & pharmaceutical bulletin (2001)
Published in Chemical & pharmaceutical bulletin (2001)
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Amphoteric Drugs. 3. Synthesis and Antiallergic Activity of 3-[(5,11-Dihydro[1]benzoxepino[4,3-b]pyridin-11-ylidene)piperidino]propionic Acid Derivatives and Related Compounds
Iwasaki, Nobuhiko, Ohashi, Tetsuo, Musoh, Keiichi, Nishino, Hiroyuki, Kado, Noriyuki, Yasuda, Shingo, Kato, Hideo, Ito, Yasuo
Published in Journal of medicinal chemistry (01.02.1995)
Published in Journal of medicinal chemistry (01.02.1995)
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Amphoteric drugs. II: Synthesis and antiallergic activity of [4-(5H-dibenzo[a,d] cyclohepten-5-ylidene) piperidino] alkanoic acid derivatives and related compounds
IWASAKI, N, SAKAGUCHI, J, OHASHI, T, YAMAZAKI, M, OGAWA, N, YASUDA, S, KOSHINAKA, E, KATO, H, ITO, Y, SAWANISHI, H
Published in Chemical & pharmaceutical bulletin (1994)
Published in Chemical & pharmaceutical bulletin (1994)
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Amphoteric Drugs. I. Synthesis and Antiallergic Activity of (4-(Diphenylmethoxy)piperidino)-, (4-(Diphenylmethyl)piperazinyl)- and (4-(Diphenylmethylene)piperidino)alkanoic Acid Derivatives
IWASAKI, Nobuhiko, SAKAGUCHI, Jun, OHASHI, Tetsuo, TAKAHARA, Eiji, OGAWA, Nobuo, YASUDA, Shingo, KOSHINAKA, Eiichi, KATO, Hideo, ITO, Yasuo, SAWANISHI, Hiroyuki
Published in Chemical & pharmaceutical bulletin (1994)
Published in Chemical & pharmaceutical bulletin (1994)
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Study on Zwitter-Ionization of Drugs. II. Synthesis and Pharmacological Activity of Some N-[3-(5H-Dibenzo[a, d]cyclohepten-5-ylidene)propyl]-N-methylamino- and N-[3-(6H-Dibenz[b, e]oxepin-11-ylidene)propyl]-N-methylamino-alkanoic Acid Derivatives and Related Compounds
MURAMATSU, Hiromi, SAWANISHI, Hiroyuki, IWASAKI, Nobuhiko, KAKIUCHI, Masato, OHASHI, Tetsuo, KATO, Hideo, ITO, Yasuo
Published in Chemical & pharmaceutical bulletin (1993)
Published in Chemical & pharmaceutical bulletin (1993)
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Studies on Antiallergic Agents. II. : Quantitative Structure-Activity Relationships of Novel 6-Substituted N-(1H-Tetrazol-5-yl)-2-pyrazinecarboxamides
MAKINO, Eiichi, MITANI, Kazuya, IWASAKI, Nobuhiko, KATO, Hideo, ITO, Yasuo, AZUMA, Hiroshi, FUJITA, Toshio
Published in Chemical & pharmaceutical bulletin (1990)
Published in Chemical & pharmaceutical bulletin (1990)
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Hit-to-lead optimization of 1,4-dihydroindeno[1,2- c]pyrazoles as a novel class of KDR kinase inhibitors
Dinges, Jürgen, Akritopoulou-Zanze, Irini, Arnold, Lee D., Barlozzari, Teresa, Bousquet, Peter F., Cunha, George A., Ericsson, Anna M., Iwasaki, Nobuhiko, Michaelides, Michael R., Ogawa, Nobuo, Phelan, Kathleen M., Rafferty, Paul, Sowin, Thomas J., Stewart, Kent D., Tokuyama, Ryukou, Xia, Zhiren, Zhang, Henry Q.
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
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