Identification of a Selective, Non-Prostanoid EP2 Receptor Agonist for the Treatment of Glaucoma: Omidenepag and its Prodrug Omidenepag Isopropyl
Iwamura, Ryo, Tanaka, Masayuki, Okanari, Eiji, Kirihara, Tomoko, Odani-Kawabata, Noriko, Shams, Naveed, Yoneda, Kenji
Published in Journal of medicinal chemistry (09.08.2018)
Published in Journal of medicinal chemistry (09.08.2018)
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Downregulation of COL12A1 and COL13A1 by a selective EP2 receptor agonist, omidenepag, in human trabecular meshwork cells
Kumon, Masashi, Fuwa, Masahiro, Shimazaki, Atsushi, Odani-Kawabata, Noriko, Iwamura, Ryo, Yoneda, Kenji, Kato, Masatomo
Published in PloS one (11.01.2023)
Published in PloS one (11.01.2023)
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Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, on Aqueous Humor Dynamics in Laser-Induced Ocular Hypertensive Monkeys
Fuwa, Masahiro, Toris, Carol B, Fan, Shan, Taniguchi, Takazumi, Ichikawa, Masaki, Odani-Kawabata, Noriko, Iwamura, Ryo, Yoneda, Kenji, Matsugi, Takeshi, Shams, Naveed K, Zhang, Jin-Zhong
Published in Journal of ocular pharmacology and therapeutics (01.09.2018)
Published in Journal of ocular pharmacology and therapeutics (01.09.2018)
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Pharmacologic Characterization of Omidenepag Isopropyl, a Novel Selective EP2 Receptor Agonist, as an Ocular Hypotensive Agent
Kirihara, Tomoko, Taniguchi, Takazumi, Yamamura, Kenzo, Iwamura, Ryo, Yoneda, Kenji, Odani-Kawabata, Noriko, Shimazaki, Atsushi, Matsugi, Takeshi, Shams, Naveed, Zhang, Jin-Zhong
Published in Investigative ophthalmology & visual science (01.01.2018)
Published in Investigative ophthalmology & visual science (01.01.2018)
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Effects of the Selective EP2 Receptor Agonist Omidenepag on Adipocyte Differentiation in 3T3-L1 Cells
Yamamoto, Yasuko, Taniguchi, Takazumi, Inazumi, Tomoaki, Iwamura, Ryo, Yoneda, Kenji, Odani-Kawabata, Noriko, Matsugi, Takeshi, Sugimoto, Yukihiko, Shams, Naveed K
Published in Journal of ocular pharmacology and therapeutics (01.04.2020)
Published in Journal of ocular pharmacology and therapeutics (01.04.2020)
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Antiplatelet action of R‐99224, an active metabolite of a novel thienopyridine‐type Gi‐linked P2T antagonist, CS‐747
Sugidachi, Atsuhiro, Asai, Fumitoshi, Yoneda, Kenji, Iwamura, Ryo, Ogawa, Taketoshi, Otsuguro, Ken‐ichi, Koike, Hiroyuki
Published in British journal of pharmacology (01.01.2001)
Published in British journal of pharmacology (01.01.2001)
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Additive Intraocular Pressure-Lowering Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, Combined with Existing Antiglaucoma Agents in Conscious Ocular Normotensive Monkeys
Fuwa, Masahiro, Shimazaki, Atsushi, Odani-Kawabata, Noriko, Kirihara, Tomoko, Taniguchi, Takazumi, Iwamura, Ryo, Yoneda, Kenji, Kato, Masatomo, Morishima, Kenji, Shams, Naveed K
Published in Journal of ocular pharmacology and therapeutics (01.05.2021)
Published in Journal of ocular pharmacology and therapeutics (01.05.2021)
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이환식 함질소 헤테로환 화합물
IWAMURA RYO, NAKAJIMA TATSUO, TSUBOIKE KAZUNARI, HAYASHI NORIMITSU, ISHIZAWA KOUHEI, TSUZAKI YASUNORI
Year of Publication 16.04.2019
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Year of Publication 16.04.2019
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BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND
TSUZAKI, Yasunori, NAKAJIMA, Tatsuo, ISHIZAWA, Kouhei, HAYASHI, Norimitsu, TSUBOIKE, Kazunari, IWAMURA, Ryo
Year of Publication 01.03.2018
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Year of Publication 01.03.2018
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IWAMURA RYO, YAMAMOTO YASUHITO, SETOGUCHI HIROYUKI, TAKAMA AKIRA, KUNO YUKA, AKAZA HIROTO, TSUZAKI YASUNORI
Year of Publication 12.01.2018
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Year of Publication 12.01.2018
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CRYSTAL OF SALT OF NOVEL 3-AZABICYCLO[3.1.0]HEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
TSUZAKI Yasunori, TAKAMA Akira, AKAZA Hiroto, KUNO Yuka, SETOGUCHI Hiroyuki, IWAMURA Ryo, YAMAMOTO Yasuhito
Year of Publication 24.11.2016
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Year of Publication 24.11.2016
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Antiplatelet action of R‐99224, an active metabolite of a novel thienopyridine‐type G i ‐linked P2T antagonist, CS‐747
Sugidachi, Atsuhiro, Asai, Fumitoshi, Yoneda, Kenji, Iwamura, Ryo, Ogawa, Taketoshi, Otsuguro, Ken‐ichi, Koike, Hiroyuki
Published in British journal of pharmacology (29.01.2009)
Published in British journal of pharmacology (29.01.2009)
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NOVEL 3-AZABICYCLO[3.1.0]HEXANE DRIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES
SHIMIZU MOTOHISA, TANIKO KAORI, KURUMAZUKA DAISUKE, IWAMURA RYO, IMURA YUUKI, HARADA SATOKO, OKABE MORIO, SETOGUCHI HIROYUKI, IZUCHI TORU, MIYAZAWA TOSHIYUKI, KANEKO TATSUROH, AKAZA HIROTO, KIMURA TOMIO, TSUZAKI YASUNORI
Year of Publication 06.07.2016
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Year of Publication 06.07.2016
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SULFONAMIDE COMPOUNDS
OKANARI, EIJI, KATSUBE, TETSUSHI, SHIGETOMI, MANABU, IWAMURA, RYO, TOKUNAGA, YASUNORI
Year of Publication 17.03.2011
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Year of Publication 17.03.2011
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