Aging and Clonal Behavior of Hematopoietic Stem Cells
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Published in International journal of molecular sciences (09.02.2022)
Published in International journal of molecular sciences (09.02.2022)
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Published in Nature communications (16.05.2022)
Published in Nature communications (16.05.2022)
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Multifaceted role of the polycomb-group gene EZH2 in hematological malignancies
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Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
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Published in Nature communications (26.10.2021)
Published in Nature communications (26.10.2021)
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Overexpression of Hmga2 activates Igf2bp2 and remodels transcriptional program of Tet2-deficient stem cells in myeloid transformation
Bai, Jie, Yokomizo-Nakano, Takako, Kubota, Sho, Sun, Yuqi, Kanai, Akinori, Iimori, Mihoko, Harada, Hironori, Iwama, Atsushi, Sashida, Goro
Published in Oncogene (25.02.2021)
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Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity
Loo, Tze Mun, Kamachi, Fumitaka, Watanabe, Yoshihiro, Yoshimoto, Shin, Kanda, Hiroaki, Arai, Yuriko, Nakajima-Takagi, Yaeko, Iwama, Atsushi, Koga, Tomoaki, Sugimoto, Yukihiko, Ozawa, Takayuki, Nakamura, Masaru, Kumagai, Miho, Watashi, Koichi, Taketo, Makoto M., Aoki, Tomohiro, Narumiya, Shuh, Oshima, Masanobu, Arita, Makoto, Hara, Eiji, Ohtani, Naoko
Published in Cancer discovery (01.05.2017)
Published in Cancer discovery (01.05.2017)
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Chemically defined cytokine-free expansion of human haematopoietic stem cells
Sakurai, Masatoshi, Ishitsuka, Kantaro, Ito, Ryoji, Wilkinson, Adam C., Kimura, Takaharu, Mizutani, Eiji, Nishikii, Hidekazu, Sudo, Kazuhiro, Becker, Hans Jiro, Takemoto, Hiroshi, Sano, Tsubasa, Kataoka, Keisuke, Takahashi, Satoshi, Nakamura, Yukio, Kent, David G., Iwama, Atsushi, Chiba, Shigeru, Okamoto, Shinichiro, Nakauchi, Hiromitsu, Yamazaki, Satoshi
Published in Nature (London) (02.03.2023)
Published in Nature (London) (02.03.2023)
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Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner
Mochizuki-Kashio, Makiko, Aoyama, Kazumasa, Sashida, Goro, Oshima, Motohiko, Tomioka, Takahisa, Muto, Tomoya, Wang, Changshan, Iwama, Atsushi
Published in Blood (03.09.2015)
Published in Blood (03.09.2015)
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Obesity accelerates hair thinning by stem cell-centric converging mechanisms
Morinaga, Hironobu, Mohri, Yasuaki, Grachtchouk, Marina, Asakawa, Kyosuke, Matsumura, Hiroyuki, Oshima, Motohiko, Takayama, Naoya, Kato, Tomoki, Nishimori, Yuriko, Sorimachi, Yuriko, Takubo, Keiyo, Suganami, Takayoshi, Iwama, Atsushi, Iwakura, Yoichiro, Dlugosz, Andrzej A., Nishimura, Emi K.
Published in Nature (London) (08.07.2021)
Published in Nature (London) (08.07.2021)
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Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche
Kuribayashi, Wakako, Oshima, Motohiko, Itokawa, Naoki, Koide, Shuhei, Nakajima-Takagi, Yaeko, Yamashita, Masayuki, Yamazaki, Satoshi, Rahmutulla, Bahityar, Miura, Fumihito, Ito, Takashi, Kaneda, Atsushi, Iwama, Atsushi
Published in The Journal of experimental medicine (01.03.2021)
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Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition
Rizq, Ola, Mimura, Naoya, Oshima, Motohiko, Saraya, Atsunori, Koide, Shuhei, Kato, Yuko, Aoyama, Kazumasa, Nakajima-Takagi, Yaeko, Wang, Changshan, Chiba, Tetsuhiro, Ma, Anqi, Jin, Jian, Iseki, Tohru, Nakaseko, Chiaki, Iwama, Atsushi
Published in Clinical cancer research (15.08.2017)
Published in Clinical cancer research (15.08.2017)
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Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm
Kubota, Sho, Tokunaga, Kenji, Umezu, Tomohiro, Yokomizo-Nakano, Takako, Sun, Yuqi, Oshima, Motohiko, Tan, Kar Tong, Yang, Henry, Kanai, Akinori, Iwanaga, Eisaku, Asou, Norio, Maeda, Takahiro, Nakagata, Naomi, Iwama, Atsushi, Ohyashiki, Kazuma, Osato, Motomi, Sashida, Goro
Published in Nature communications (10.04.2019)
Published in Nature communications (10.04.2019)
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