Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study
Kasugai, Kunio, Iwai, Hisakazu, Kuboyama, Noboru, Yoshikawa, Aya, Fukudo, Shin
Published in Journal of gastroenterology (01.06.2019)
Published in Journal of gastroenterology (01.06.2019)
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Cross‐over study in hyperammonemia patients for efficacy, safety, and acceptability of a new lactulose preparation (SK‐1202) compared to approved drug
Yoshiji, Hitoshi, Karino, Yoshiyasu, Suzuki, Yoshiyuki, Suzuki, Fumitaka, Uejima, Masakazu, Aikata, Hiroshi, Chayama, Kazuaki, Iwai, Hisakazu, Suzuki, Eiji, Kumada, Hiromitsu
Published in Hepatology research (01.12.2018)
Published in Hepatology research (01.12.2018)
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Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
Ohkura, Takako, Ohta, Kunihiro, Nagao, Takuya, Kusumoto, Kumiko, Koeda, Akiko, Ueda, Tadayoshi, Jomura, Tomoko, Ikeya, Takeshi, Ozeki, Emiko, Wada, Kazuki, Naitoh, Kazushi, Inoue, Yukiko, Takahashi, Naoki, Iwai, Hisakazu, Arakawa, Hiroshi, Ogihara, Takuo
Published in Drug metabolism and pharmacokinetics (2014)
Published in Drug metabolism and pharmacokinetics (2014)
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Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Ogihara, Takuo, Iwai, Hisakazu, Inoue, Yukiko, Katagi, Jun, Matsumoto, Norihito, Motoi-Ohtsuji, Makiko, Kakiki, Motoharu, Kaneda, Shinya, Nagao, Takuya, Kusumoto, Kumiko, Ozeki, Emiko, Jomura, Tomoko, Tanaka, Sho, Ueda, Tadayoshi, Ohta, Kunihiro, Ohkura, Takako, Arakawa, Hiroshi, Nagai, Daichi
Published in Fundamental Toxicological Sciences (2015)
Published in Fundamental Toxicological Sciences (2015)
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Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
Takako OHKURA, Kunihiro OHTA, Takuya NAGAO, Kumiko KUSUMOTO, Akiko KOEDA, Tadayoshi UEDA, Tomoko JOMURA, Takeshi IKEYA, Emiko OZEKI, Kazuki WADA, Kazushi NAITOH, Yukiko INOUE, Naoki TAKAHASHI, Hisakazu IWAI, Hiroshi ARAKAWA, Takuo OGIHARA
Published in DRUG METABOLISM AND PHARMACOKINETICS (25.10.2014)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (25.10.2014)
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2-Bromopropane-Induced Hypoplasia of Bone Marrow in Male Rats
Nakajima, Tamie, Shimodaira, Shigetaka, Ichihara, Gaku, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Ichikawa, Ichihito, Kamijima, Michihiro, Yu, Xiaozhong, Xie, Zhelin, Kondo, Hidetaka, Takeuchi, Yasuhiro
Published in Journal of Occupational Health (01.07.1997)
Published in Journal of Occupational Health (01.07.1997)
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Histopathologic Findings of Bone Marrow Induced by 2-Bromopropane in Male Rats
Nakajima, Tamie, Shimodaira, Shigetaka, Ichihara, Gaku, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Ichikawa, Ichihito, Kamijima, Michihiro, Yu, Xiaozhong, Xie, Zhelin, Kondo, Hidetaka, Takeuchi, Yasuhiro
Published in Journal of Occupational Health (01.04.1997)
Published in Journal of Occupational Health (01.04.1997)
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1-Bromopropane, an Alternative to Ozone Layer Depleting Solvents, Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Exposure
Ichihara, Gaku, Kitoh, Junzoh, Yu, Xiaozhong, Asaeda, Nobuyuki, Iwai, Hisakazu, Kumazawa, Toshihiko, Shibata, Eiji, Yamada, Tetsuya, Wang, Hailan, Xie, Zhenlin, Takeuchi, Yasuhiro
Published in Toxicological sciences (01.05.2000)
Published in Toxicological sciences (01.05.2000)
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Reproductive Toxicity of 1-Bromopropane, a Newly Introduced Alternative to Ozone Layer Depleting Solvents, in Male Rats
Ichihara, Gaku, Yu, Xiaozhong, Kitoh, Junzoh, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Shibata, Eiji, Yamada, Tetsuya, Wang, Hailan, Xie, Zhenlin, Maeda, Kei-ichiro, Tsukamura, Hiroko, Takeuchi, Yasuhiro
Published in Toxicological sciences (01.04.2000)
Published in Toxicological sciences (01.04.2000)
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NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME
CHIKAMATSU KAORI, MIYOSHI MIKA, MURAKAMI SEI, YAMASHITA TOKUYUKI, IWAI HISAKAZU, IZUCHI TOHRU, GOTO IZUMI, KASUGAI NOBUYOSHI, FUJIEDA HIROKI, MIYAZAWA TOSHIYUKI, SUZUKI KIMIE, KATAOKA DAISUKE, SEIFERT HANS JUERGEN MARKUS, LANG MARTIN, WOLF KAARINA KRISTINA, KATO NORIYASU, TSURUTA NOBUAKI, KATAOKA HIROYO, HIRAMATSU NAOKI, SAKAIRI MASAO, YAMADA YURIE, WATANABE NOBUHIDE, HARADA SATOKO, TAKAHASHI NAOKI, MAKINO MITSUHIRO, NAGAI KAZUSHIGE, KOGAMI MASAKAZU
Year of Publication 29.08.2012
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Year of Publication 29.08.2012
Patent
NOVEL THIOPHENECARBOXAMIDE DERIVATIVES AND USE THEREOF AS MEDICINE
CHIKAMATSU KAORI, MIYOSHI MIKA, MURAKAMI SEI, IZUCHI TOHRU, IWAI HISAKAZU, KUNO YUKA, YAMASHITA TOKUYUKI, GOTO IZUMI, KASUGAI NOBUYOSHI, FUJIEDA HIROKI, MIYAZAWA TOSHIYUKI, SUZUKI KIMIE, SEIFERT HANS-JUERGEN MARKUS, KATAOKA DAISUKE, LANG MARTIN, WOLF KAARINA KRISTINA, KATO NORIYASU, KONDOH YURIE, TSURUTA NOBUAKI, KATAOKA HIROYO, HIRAMATSU NAOKI, SAKAIRI MASAO, WATANABE NOBUHIDE, HARADA SATOKO, TAKAHASHI NAOKI, MAKINO MITSUHIRO, NAGAI KAZUSHIGE, KOGAMI MASAKAZU
Year of Publication 29.12.2011
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Year of Publication 29.12.2011
Patent
NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME
CHIKAMATSU KAORI, MIYOSHI MIKA, MURAKAMI SEI, YAMASHITA TOKUYUKI, IWAI HISAKAZU, IZUCHI TOHRU, GOTO IZUMI, KASUGAI NOBUYOSHI, FUJIEDA HIROKI, MIYAZAWA TOSHIYUKI, SUZUKI KIMIE, SEIFERT HANS-JUERGEN MARKUS, KATAOKA DAISUKE, LANG MARTIN, WOLF KAARINA KRISTINA, KATO NORIYASU, KONDOH YURIE, TSURUTA NOBUAKI, KATAOKA HIROYO, HIRAMATSU NAOKI, SAKAIRI MASAO, WATANABE NOBUHIDE, HARADA SATOKO, TAKAHASHI NAOKI, MAKINO MITSUHIRO, NAGAI KAZUSHIGE, KOGAMI MASAKAZU
Year of Publication 29.12.2010
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Year of Publication 29.12.2010
Patent
A case of Fabry's disease, fifty-five years old female, diagnosed on the basis of endomyocardial biopsy findings
Nunoda, Shin-ichi, Genda, Akira, Hifumi, Senshu, Taga, Kuniaki, Yasuda, Kikuo, Shimizu, Masami, Iwai, Hisakazu, Takeda, Ryoyu, Taniguchi, Noboru
Published in Shinzo (25.05.1983)
Published in Shinzo (25.05.1983)
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A case of aortitis syndrome associated with perimyocarditis
Sugihara, Norihiko, Genda, Akira, Nakayama, Akira, Iwai, Hisakazu, Nunoda, Shin-ichi, Mizuno, Sumio, Namura, Masanobu, Igarashi, Yutaka, Suematsu, Tetsuo, Horita, Yuki, Takeda, Ryoyu
Published in Shinzo (15.11.1984)
Published in Shinzo (15.11.1984)
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An autopsy case of diabetic cardiomyopathy
Yasuda, Kikuo, Genda, Akira, Taga, Kuniaki, Shimizu, Masami, Iwai, Hisakazu, Nunoda, Shinichi, Takeda, Ryoyu, Nakanuma, Yasuji, Ota, Goroku, Takeshi, Tadayoshi
Published in Shinzo (25.02.1984)
Published in Shinzo (25.02.1984)
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