Estimation of changes in serum creatinine and creatinine clearance caused by renal transporter inhibition in healthy subjects
Nakada, Tomohisa, Kudo, Toshiyuki, Kume, Toshiyuki, Kusuhara, Hiroyuki, Ito, Kiyomi
Published in Drug metabolism and pharmacokinetics (01.08.2019)
Published in Drug metabolism and pharmacokinetics (01.08.2019)
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Journal Article
Caffeine consumption as a risk factor for childhood and adolescence migraine
Hikita, Toshiyuki, Goda, Hitomi, Ogawa, Yasuko, Kudo, Toshiyuki, Ito, Kiyomi
Published in Pediatrics international (01.01.2023)
Published in Pediatrics international (01.01.2023)
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Journal Article
Use of a Physiologically Based Pharmacokinetic Model for Quantitative Prediction of Drug–Drug Interactions via CYP3A4 and Estimation of the Intestinal Availability of CYP3A4 Substrates
Mano, Yoko, Sugiyama, Yuichi, Ito, Kiyomi
Published in Journal of pharmaceutical sciences (01.09.2015)
Published in Journal of pharmaceutical sciences (01.09.2015)
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Journal Article
Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease
Yamagishi, Yoshiaki, Kudo, Toshiyuki, Oyumi, Masafumi, Sakamoto, Yusuke, Takahashi, Kazuki, Akashi, Taiki, Kobayashi, Shohei, Kawakami, Takeaki, Goda, Hitomi, Sato, Yasuhiro, Mimaki, Masakazu, Kodama, Hiroko, Munakata, Mitsutoshi, Makino, Kosho, Takahashi, Hideyo, Fukami, Toshiro, Ito, Kiyomi
Published in Pharmaceutical research (01.08.2021)
Published in Pharmaceutical research (01.08.2021)
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Journal Article
Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers
Funakoshi, Ryohkan, Tomoda, Yukana, Kudo, Toshiyuki, Furihata, Kenichi, Kusuhara, Hiroyuki, Ito, Kiyomi
Published in British journal of clinical pharmacology (01.07.2019)
Published in British journal of clinical pharmacology (01.07.2019)
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Journal Article
Quantitative analysis of elevation of serum creatinine via renal transporter inhibition by trimethoprim in healthy subjects using physiologically-based pharmacokinetic model
Nakada, Tomohisa, Kudo, Toshiyuki, Kume, Toshiyuki, Kusuhara, Hiroyuki, Ito, Kiyomi
Published in Drug metabolism and pharmacokinetics (01.02.2018)
Published in Drug metabolism and pharmacokinetics (01.02.2018)
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Journal Article
Analysis of the repaglinide concentration increase produced by gemfibrozil and itraconazole based on the inhibition of the hepatic uptake transporter and metabolic enzymes
Kudo, Toshiyuki, Hisaka, Akihiro, Sugiyama, Yuichi, Ito, Kiyomi
Published in Drug metabolism and disposition (01.02.2013)
Published in Drug metabolism and disposition (01.02.2013)
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Journal Article
Gastroprotective Effect of Enteral Nutrition Formula in Mice Injected Subcutaneously with Indomethacin
Yamagishi, Yoshiaki, Saiki, Rei, Yoshimi, Takeshi, Kudo, Toshiyuki, Ito, Kiyomi
Published in Nutrients (21.09.2021)
Published in Nutrients (21.09.2021)
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Journal Article
Strategies to improve the prediction accuracy of hepatic intrinsic clearance of three antidiabetic drugs: Application of the extended clearance concept and consideration of the effect of albumin on CYP2C metabolism and OATP1B-mediated hepatic uptake
Fujino, Ryo, Hashizume, Kenta, Aoyama, Shinsuke, Maeda, Kazuya, Ito, Kiyomi, Toshimoto, Kota, Lee, Wooin, Ninomiya, Shin-ichi, Sugiyama, Yuichi
Published in European journal of pharmaceutical sciences (01.12.2018)
Published in European journal of pharmaceutical sciences (01.12.2018)
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Journal Article
Anti-Obesity and Anti-Diabetic Effects of Acacia Polyphenol in Obese Diabetic KKAy Mice Fed High-Fat Diet
Ikarashi, Nobutomo, Toda, Takahiro, Okaniwa, Takehiro, Ito, Kiyomi, Ochiai, Wataru, Sugiyama, Kiyoshi
Published in Evidence-based complementary and alternative medicine (01.01.2011)
Published in Evidence-based complementary and alternative medicine (01.01.2011)
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Journal Article
Physiologically based pharmacokinetic model analysis of the inhibitory effect of vonoprazan on the metabolic activation of proguanil
Okubo, Kenjiro, Kudo, Toshiyuki, Yoshihara, Sae, Nakabayashi, Yu, Nakauchi, Kana, Tanaka, Akimi, Saito, Moe, Tsujisawa, Ayumi, Goda, Hitomi, Yamagishi, Yoshiaki, Otake, Chinatsu, Makino, Kosho, Takahashi, Hideyo, Ito, Kiyomi
Published in Drug metabolism and pharmacokinetics (01.02.2024)
Published in Drug metabolism and pharmacokinetics (01.02.2024)
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Journal Article
Chorea-like symptoms and high blood concentration of ceftriaxone in a patient undergoing hemodialysis: A case report
Yokoyama, Yoshiaki, Hosokawa, Naoto, Kudo, Toshiyuki, Goda, Hitomi, Ito, Kiyomi, Suzuki, Masanori, Funakoshi, Ryohkan
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01.03.2020)
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01.03.2020)
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Journal Article
Estimation of the Contribution of CYP2C8 and CYP3A4 in Repaglinide Metabolism by Human Liver Microsomes Under Various Buffer Conditions
Kudo, Toshiyuki, Goda, Hitomi, Yokosuka, Yuki, Tanaka, Ryo, Komatsu, Seina, Ito, Kiyomi
Published in Journal of pharmaceutical sciences (01.09.2017)
Published in Journal of pharmaceutical sciences (01.09.2017)
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Journal Article
Chemoselective Demethylation of Methoxypyridine
Makino, Kosho, Hasegawa, Yumi, Inoue, Takahide, Araki, Koji, Tabata, Hidetsugu, Oshitari, Tetsuta, Ito, Kiyomi, Natsugari, Hideaki, Takahashi, Hideyo
Published in Synlett (01.05.2019)
Published in Synlett (01.05.2019)
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Journal Article
Omega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells
Pizato, Nathalia, Luzete, Beatriz Christina, Kiffer, Larissa Fernanda Melo Vasconcelos, Corrêa, Luís Henrique, de Oliveira Santos, Igor, Assumpção, José Antônio Fagundes, Ito, Marina Kiyomi, Magalhães, Kelly Grace
Published in Scientific reports (31.01.2018)
Published in Scientific reports (31.01.2018)
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