Protein Engineering on Human Recombinant Follistatin: Enhancing Pharmacokinetic Characteristics for Therapeutic Application
Shen, Chuan, Iskenderian, Andrea, Lundberg, Dianna, He, Tao, Palmieri, Kathleen, Crooker, Robert, Deng, Qingwei, Traylor, Matthew, Gu, Sheng, Rong, Haojing, Ehmann, David, Pescatore, Brian, Strack-Logue, Bettina, Romashko, Alla, Baviello, George, Gill, John, Zhang, Bohong, Meiyappan, Muthuraman, Pan, Clark, Norton, Angela W
Published in The Journal of pharmacology and experimental therapeutics (01.08.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2018)
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Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone
Iskenderian, Andrea, Liu, Nan, Deng, Qingwei, Huang, Yan, Shen, Chuan, Palmieri, Kathleen, Crooker, Robert, Lundberg, Dianna, Kastrapeli, Niksa, Pescatore, Brian, Romashko, Alla, Dumas, John, Comeau, Robert, Norton, Angela, Pan, Jing, Rong, Haojing, Derakhchan, Katayoun, Ehmann, David E
Published in Skeletal muscle (27.10.2018)
Published in Skeletal muscle (27.10.2018)
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Leveraging Quantitative Systems Pharmacology Approach into Development of Human Recombinant Follistatin Fusion Protein for Duchenne Muscular Dystrophy
Nguyen, Hoa Q., Iskenderian, Andrea, Ehmann, David, Jasper, Paul, Zhang, Zhiwei, Rong, Haojing, Welty, Devin, Narayanan, Rangaraj
Published in CPT: pharmacometrics and systems pharmacology (01.06.2020)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2020)
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Human Sulfatase 2 inhibits in vivo tumor growth of MDA-MB-231 human breast cancer xenografts
Peterson, Sarah M, Iskenderian, Andrea, Cook, Lynette, Romashko, Alla, Tobin, Kristen, Jones, Michael, Norton, Angela, Gómez-Yafal, Alicia, Heartlein, Michael W, Concino, Michael F, Liaw, Lucy, Martini, Paolo G V
Published in BMC cancer (13.08.2010)
Published in BMC cancer (13.08.2010)
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490c – C1Inh: A Novel Therapeutic Target to Treat Biliary Atresia and Liver Fibrosis
Navabi, Nazanin, Gutta, Sridevi, Mourya, Reena, Holmes, Kevin, Iskenderian, Andrea, Islam, Rizwana, Rong, Haojing, Norton, Angela, Sypek, Joseph, Shivakumar, Pranavkumar
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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Expression, purification, and characterization of human mannose-6-phosphate receptor – Extra cellular domain from a stable cell line utilizing a small molecule biomimetic of the mannose-6-phosphate moiety
Dwyer, Brian, Lundberg, Dianna, Iskenderian, Andrea, Strack-Logue, Bettina, Pescatore, Brian, Norton, Angela W., Xu, Jin, Meiyappan, Muthuraman, Concino, Michael F., Zhang, Bohong
Published in Protein expression and purification (01.06.2020)
Published in Protein expression and purification (01.06.2020)
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TREATMENT OF SANFILIPPO SYNDROME TYPE B
PAN JING, CALIAS PERICLES, CONCINO MICHAEL F, ZHANG BOHONG, PFEIFER RICHARD, ROMASHKO ALLA, LUNDBERG DIANNA, MARTINI PAOLO, HOLMES KEVIN, NORTON ANGELA, MEIYAPPAN MUTHURAMAN, HUANG YAN, ALESSANDRINI MARY, STRACK LOGUE BETTINA, ISKENDERIAN ANDREA
Year of Publication 29.04.2013
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Year of Publication 29.04.2013
Patent
PROTÉINES DE FUSION DE L'INHIBITEUR DE LA C1 ESTÉRASE ET LEURS UTILISATIONS
NORTON, Angela, ISKENDERIAN, Andrea, STRACK-LOGUE, Bettina, PAN, Clark
Year of Publication 15.09.2021
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Year of Publication 15.09.2021
Patent
C1 ESTERASE INHIBITOR FUSION PROTEINS AND USES THEREOF
Pan, Clark, Strack-Logue, Bettina, Norton, Angela, Iskenderian, Andrea
Year of Publication 11.03.2021
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Year of Publication 11.03.2021
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C1 ESTERASE INHIBITOR FUSION PROTEINS AND USES THEREOF
NORTON, Angela, ISKENDERIAN, Andrea, STRACK-LOGUE, Bettina, PAN, Clark
Year of Publication 27.01.2021
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Year of Publication 27.01.2021
Patent
C1 esterase inhibitor fusion proteins and uses thereof
Pan, Clark, Strack-Logue, Bettina, Norton, Angela, Iskenderian, Andrea
Year of Publication 19.11.2020
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Year of Publication 19.11.2020
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Recombinant placenta growth factor for treating Duchenne muscular dystrophy
Meiyappan, Muthuraman, Concino, Michael F, Norton, Angela, Iskenderian, Andrea
Year of Publication 04.08.2020
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Year of Publication 04.08.2020
Patent
C1 ESTERASE INHIBITOR FUSION PROTEINS AND USES THEREOF
NORTON, Angela, ISKENDERIAN, Andrea, STRACK-LOGUE, Bettina, PAN, Clark
Year of Publication 27.05.2020
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Year of Publication 27.05.2020
Patent
PLACENTA GROWTH FACTOR IN TREATING DUCHENNE MUSCULAR DYSTROPHY
CONCINO, Michael F, NORTON, Angela, ISKENDERIAN, Andrea, MEIYAPPAN, Muthuraman
Year of Publication 08.04.2020
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Year of Publication 08.04.2020
Patent