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Published in Bioorganic & medicinal chemistry (01.11.2018)
Published in Bioorganic & medicinal chemistry (01.11.2018)
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Design, Synthesis and Biological Evaluation of Novel Triazole N -acylhydrazone Hybrids for Alzheimer's Disease
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Published in Molecules (Basel, Switzerland) (10.07.2020)
Published in Molecules (Basel, Switzerland) (10.07.2020)
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Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling
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Published in MedChemComm (01.12.2019)
Published in MedChemComm (01.12.2019)
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Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
Cristancho Ortiz, Cindy Juliet, de Freitas Silva, Matheus, Pruccoli, Letizia, Fonseca Nadur, Nathália, de Azevedo, Luciana Luíza, Kümmerle, Arthur Eugen, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel, Leomil Coelho, Luiz Felipe, Guimarães, Marcos J, da Silva, Fernanda M. R, Castro, Newton, Gontijo, Vanessa Silva, Rojas, Viviana C. T, de Oliveira, Merelym Ketterym, Vilela, Fabiana Cardoso, Giusti-Paiva, Alexandre, Barbosa, Gisele, Lima, Lídia Moreira, Pinheiro, Gabriela Beserra, Veras, Letícia Germino, Mortari, Márcia Renata, Tarozzi, Andrea, Viegas, Claudio
Published in MedChemComm (25.05.2022)
Published in MedChemComm (25.05.2022)
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Anti-Restriction Gene Homologs Are Highly Represented in Methicillin-Resistant and Multidrug-Resistant Staphylococcus aureus ST239 and ST398: Implications for Resistance Gene Acquisitions
Silva, Deborah Nascimento Santos, Beltrame, Cristiana Ossaille, Botelho, Ana Maria Nunes, Martini, Caroline Lopes, Esteves, Matheus Assis Côrtes, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel, Figueiredo, Agnes Marie Sá
Published in Antibiotics (Basel) (08.09.2022)
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DockThor-VS: A Free Platform for Receptor-Ligand Virtual Screening
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Published in Journal of molecular biology (01.09.2024)
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Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer?s disease
Vaz, Sarah Macedo, Silva, Matheus de Freitas, Franco, Graziella dos Reis Rosa, Guimaraes, Marcos Jorge R., da Silva, Fernanda Motta R., Castro, Newton Gonsalves, Guedes, Isabella Alvim, Dardenne, Laurent E., Alves, Marina Amaral, da Costa, Rafael Garrett, Pinheiro, Gabriela Beserra, Veras, Leticia Germino, Mortari, Marcia Renata, Pruccoli, Letizia, Tarozzi, Andrea, Viegas Jr, Claudio
Published in Bioorganic & medicinal chemistry (01.10.2022)
Published in Bioorganic & medicinal chemistry (01.10.2022)
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Analysis of a novel class A β-lactamase OKP-B-6 of Klebsiella quasipneumoniae: structural characterisation and interaction with commercially available drugs
Bellini, Reinaldo, Guedes, Isabella Alvim, Ciapina, Luciane Prioli, de Vasconcelos, Ana Tereza Ribeiro, Dardenne, Laurent Emmanuel, Nicolás, Marisa Fabiana
Published in Memórias do Instituto Oswaldo Cruz (01.01.2022)
Published in Memórias do Instituto Oswaldo Cruz (01.01.2022)
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Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease
Macedo Vaz, Sarah, de Freitas Silva, Matheus, dos Reis Rosa Franco, Graziella, Jorge R. Guimarães, Marcos, Motta R. da Silva, Fernanda, Gonçalves Castro, Newton, Alvim Guedes, Isabella, Dardenne, Laurent E., Amaral Alves, Marina, Garrett da Costa, Rafael, Beserra Pinheiro, Gabriela, Germino Veras, Letícia, Renata Mortari, Márcia, Pruccoli, Letizia, Tarozzi, Andrea, Viegas, Cláudio
Published in Bioorganic & medicinal chemistry (01.10.2022)
Published in Bioorganic & medicinal chemistry (01.10.2022)
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Novel series of tacrine-tianeptine hybrids: Synthesis, cholinesterase inhibitory activity, S10013 secretion and a molecular modeling approach
Ceschi, Marco Antonio, da Costa, Jessie Sobieski, Bizarro Lopes, Joao Paulo, Camara, Viktor Saraiva, Campo, Leandra Franciscato, de Amorim Borges, Antonio Cesar, Saraiva Goncalves, Carlos Alberto, de Souza, Daniela Fraga, Konrath, Eduardo Luis, Martins Karl, Ana Luiza, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel
Published in European journal of medicinal chemistry (04.10.2016)
Published in European journal of medicinal chemistry (04.10.2016)
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Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases
Ortiz, Cindy Juliet Cristancho, Damasio, Caio Miranda, Pruccoli, Letizia, Nadur, Nathália Fonseca, de Azevedo, Luciana Luiza, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel, Kümmerle, Arthur Eugen, Tarozzi, Andrea, Viegas, Claudio
Published in Neurochemical research (01.12.2020)
Published in Neurochemical research (01.12.2020)
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Novel series of tacrine-tianeptine hybrids: Synthesis, cholinesterase inhibitory activity, S100B secretion and a molecular modeling approach
Ceschi, Marco Antonio, da Costa, Jessie Sobieski, Lopes, João Paulo Bizarro, Câmara, Viktor Saraiva, Campo, Leandra Franciscato, Borges, Antonio César de Amorim, Gonçalves, Carlos Alberto Saraiva, de Souza, Daniela Fraga, Konrath, Eduardo Luis, Karl, Ana Luiza Martins, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel
Published in European journal of medicinal chemistry (04.10.2016)
Published in European journal of medicinal chemistry (04.10.2016)
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Anti-Restriction Gene Homologs Are Highly Represented in Methicillin-Resistant and Multidrug-Resistant IStaphylococcus aureus/I ST239 and ST398: Implications for Resistance Gene Acquisitions
Silva, Deborah Nascimento Santos, Beltrame, Cristiana Ossaille, Botelho, Ana Maria Nunes, Ma, Esteves, Matheus Assis Côrtes, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel, Figueiredo, Agnes Marie Sá
Published in Antibiotics (Basel) (01.09.2022)
Published in Antibiotics (Basel) (01.09.2022)
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A unique SaeS allele overrides cell-density dependent expression of saeR and lukSF-PV in the ST30-SCCmecIV lineage of CA-MRSA
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Published in International journal of medical microbiology (01.09.2016)
Published in International journal of medical microbiology (01.09.2016)
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Synthesis of new lophine–carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling† †Electronic supplementary information (ESI) available: Graphics and extra data of in vitro and in silico experiments and detailed spectroscopic characterization. See DOI: 10.1039/c9md00358d
Lopes, João Paulo Bizarro, Silva, Luana, Ceschi, Marco Antonio, Lüdtke, Diogo Seibert, Zimmer, Aline Rigon, Ruaro, Thais Carine, Dantas, Rafael Ferreira, de Salles, Cristiane Martins Cardoso, Silva-Jr, Floriano Paes, Senger, Mario Roberto, Barbosa, Gisele, Lima, Lídia Moreira, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel
Published in MedChemComm (08.11.2019)
Published in MedChemComm (08.11.2019)
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A unique SaeS allele overrides cell-density dependent expression of saeR and lukSF-PV in the ST30-SCC mec IV lineage of CA-MRSA
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Published in International journal of medical microbiology (2016)
Published in International journal of medical microbiology (2016)
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molécula híbrida contendo núcleos lofina e derivados de carboidratos, composição farmacêutica, processo de síntese e seus usos
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Year of Publication 13.08.2019
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