Search Results - "ISAACSON, Jeffrey" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

by Lin, Kevin K, Harrell, Maria I, Oza, Amit M, Oaknin, Ana, Ray-Coquard, Isabelle, Tinker, Anna V, Helman, Elena, Radke, Marc R, Say, Carmen, Vo, Lan-Thanh, Mann, Elaina, Isaacson, Jeffrey D, Maloney, Lara, O'Malley, David M, Chambers, Setsuko K, Kaufmann, Scott H, Scott, Clare L, Konecny, Gottfried E, Coleman, Robert L, Sun, James X, Giordano, Heidi, Brenton, James D, Harding, Thomas C, McNeish, Iain A, Swisher, Elizabeth M
Published in Cancer discovery (01.02.2019)

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$A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone‐refractory prostate cancer$

A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone‐refractory prostate cancer

by Carducci, Michael A., Saad, Fred, Abrahamsson, Per‐Anders, Dearnaley, David P., Schulman, Claude C., North, Scott A., Sleep, Darryl J., Isaacson, Jeffrey D., Nelson, Joel B.
Published in Cancer (01.11.2007)

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$Atrasentan, an Endothelin-Receptor Antagonist for Refractory Adenocarcinomas: Safety and Pharmacokinetics$

Atrasentan, an Endothelin-Receptor Antagonist for Refractory Adenocarcinomas: Safety and Pharmacokinetics

by CARDUCCI, Michael A, NELSON, Joel B, JANUS, Todd J, ANDRE, Amy, HOSMANE, Balakrishna S, PADLEY, Robert J, BOWLING, M. Kathy, ROGERS, Theresa, EISENBERGER, Mario A, SINIBALDI, Victoria, DONEHOWER, Ross, LEAHY, Terri L, CARR, Robert A, ISAACSON, Jeffrey D
Published in Journal of clinical oncology (15.04.2002)

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Pharmacokinetic-Pharmacodynamic Analysis of Lopinavir-Ritonavir in Combination with Efavirenz and Two Nucleoside Reverse Transcriptase Inhibitors in Extensively Pretreated Human Immunodeficiency Virus-Infected Patients

Pharmacokinetic-Pharmacodynamic Analysis of Lopinavir-Ritonavir in Combination with Efavirenz and Two Nucleoside Reverse Transcriptase Inhibitors in Extensively Pretreated Human Immunodeficiency Virus-Infected Patients

by ANN HSU, ISAACSON, Jeffrey, RODE, Richard, KEMPF, Dale J, GRANNEMAN, G. Richard, SUN, Eugene, BRUN, Scott, BERNSTEIN, Barry, LAM, Wayne, BERTZ, Richard, FOIT, Cheryl, RYNKIEWICZ, Karen, RICHARDS, Bruce, KING, Martin
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)

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Analysis of the virological response with respect to baseline viral phenotype and genotype in protease inhibitor-experienced HIV-1-infected patients receiving lopinavir/ritonavir therapy

Analysis of the virological response with respect to baseline viral phenotype and genotype in protease inhibitor-experienced HIV-1-infected patients receiving lopinavir/ritonavir therapy

by KEMPF, Dale J, ISAACSON, Jeffrey D, KING, Martin S, BRUN, Scott C, SYLTE, Jacquelyn, RICHARDS, Bruce, BERNSTEIN, Barry, RODE, Richard, SUN, Eugene
Published in Antiviral therapy (01.09.2002)

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$Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer$

Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer

by ZONNENBERG, Bernard A, GROENEWEGEN, Gerard, JANUS, Todd J, LEAHY, Terri W, HUMERICKHOUSE, Rod A, ISAACSON, Jeffrey D, CARR, Robert A, VOEST, Emile
Published in Clinical cancer research (01.08.2003)

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Clinical observation of liver chemistry abnormalities in asthmatics

Clinical observation of liver chemistry abnormalities in asthmatics

by Katz, David A, Isaacson, Jeffrey D, Han, Lixin, Drajesk, Jeffrey F, Comer, Gail M, Heath-Chiozzi, Margo E
Published in Current drug safety (01.09.2009)

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Identification of Genotypic Changes in Human Immunodeficiency Virus Protease That Correlate with Reduced Susceptibility to the Protease Inhibitor Lopinavir among Viral Isolates from Protease Inhibitor-Experienced Patients

Identification of Genotypic Changes in Human Immunodeficiency Virus Protease That Correlate with Reduced Susceptibility to the Protease Inhibitor Lopinavir among Viral Isolates from Protease Inhibitor-Experienced Patients

by Kempf, D J, Isaacson, J D, King, M S, Brun, S C, Xu, Y, Real, K, Bernstein, B M, Japour, A J, Sun, E, Rode, R A
Published in Journal of Virology (01.08.2001)

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Lack of correlation between SREBF1 genotype and hyperlipidemia in individuals treated with highly active antiretroviral therapy

Lack of correlation between SREBF1 genotype and hyperlipidemia in individuals treated with highly active antiretroviral therapy

by Yang, Aiming, King, Martin S, Han, Lixin, Isaacson, Jeffrey D, Mueller, Toby, Grimm, David R, Scott, C Brun, Katz, David A
Published in AIDS (London) (26.09.2003)

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The relationship between individual-level culture and consumer decision-making styles through consumer involvement

The relationship between individual-level culture and consumer decision-making styles through consumer involvement

by Isaacson, Jeffrey Ian, Jordaan, Yolanda, van Heerden, Gené
Published in Journal of retailing and consumer services (01.03.2018)

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Increased MHC Class II and CD25 expression on lymphocytes in the absence of persistent lymphocytosis in cattle experimentally infected with bovine leukemia virus

Increased MHC Class II and CD25 expression on lymphocytes in the absence of persistent lymphocytosis in cattle experimentally infected with bovine leukemia virus

by Isaacson, Jeffrey A, Flaming, Kevan P, Roth, James A
Published in Veterinary immunology and immunopathology (31.07.1998)

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TIGER 1: A randomized, open-label, phase 2/3 study of rociletinib (CO-1686) or erlotinib as first-line treatment for EGFR-mutant non-small cell lung cancer (NSCLC)

TIGER 1: A randomized, open-label, phase 2/3 study of rociletinib (CO-1686) or erlotinib as first-line treatment for EGFR-mutant non-small cell lung cancer (NSCLC)

by Camidge, D. Ross, Wolf, Juergen, Litten, Jason B., Higashi, Linda A, Isaacson, Jeffrey D., Mok, Tony
Published in Journal of clinical oncology (20.05.2015)

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TIGER-3: A phase 3, open-label, randomized study of rociletinib vs cytotoxic chemotherapy in patients (pts) with mutant EGFR non-small cell lung cancer (NSCLC) progressing on prior EGFR TKI therapy and doublet chemotherapy

TIGER-3: A phase 3, open-label, randomized study of rociletinib vs cytotoxic chemotherapy in patients (pts) with mutant EGFR non-small cell lung cancer (NSCLC) progressing on prior EGFR TKI therapy and doublet chemotherapy

by Yang, James Chih-Hsin, Popat, Sanjay, Georgiou, Panos, Miyamoto, Emiko, Isaacson, Jeffrey D., Wakelee, Heather A.
Published in Journal of clinical oncology (20.05.2015)

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Effects of long-term infection with bovine immunodeficiency virus and/or bovine leukemia virus on antibody and lymphocyte proliferative responses in cattle

Effects of long-term infection with bovine immunodeficiency virus and/or bovine leukemia virus on antibody and lymphocyte proliferative responses in cattle

by Isaacson, Jeffrey A, Flaming, Kevan P, Roth, James A
Published in Veterinary immunology and immunopathology (31.07.1998)

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Abstract CT339: Prospective molecular identification of ovarian cancer patients benefiting from PARP inhibitor (PARPi, rucaparib) maintenance therapy - reaching beyond germline BRCA mutations

Abstract CT339: Prospective molecular identification of ovarian cancer patients benefiting from PARP inhibitor (PARPi, rucaparib) maintenance therapy - reaching beyond germline BRCA mutations

by Swisher, Elizabeth, McNeish, Iain, Coleman, Robert L., Brenton, James D., Kaufmann, Scott H., Allen, Andrew, Raponi, Mitch, Giordano, Heidi, Maloney, Lara, Isaacson, Jeffrey, Ledermann, Jonathan A.
Published in Cancer research (Chicago, Ill.) (01.10.2014)

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TIGER-3: A phase 3 multinational open-label randomized study of rociletinib vs investigator-choice chemotherapy in patients (pts) with epidermal growth factor receptor mutant-positive (EGFRm) non-small cell lung cancer (NSCLC) progressing on prior EGFR tyrosine kinase inhibitor (TKI) therapy and doublet chemotherapy

TIGER-3: A phase 3 multinational open-label randomized study of rociletinib vs investigator-choice chemotherapy in patients (pts) with epidermal growth factor receptor mutant-positive (EGFRm) non-small cell lung cancer (NSCLC) progressing on prior EGFR tyrosine kinase inhibitor (TKI) therapy and doublet chemotherapy

by Yang, James Chih-Hsin, Popat, Sanjay, Novello, Silvia, Groen, Harry J.M., Perol, Maurice, Felip, Enriqueta, Griesinger, Frank, Reckamp, Karen L., Lee, Jong-Seok, Smit, Egbert F., Blakely, Collin M., Akerley, Wallace L., Kim, Young-Chul, Bazhenova, Lyudmila, Califano, Raffaele, Hall, Richard Delmar, Georgiou, Panayiotis, Isaacson, Jeffrey D., Golsorkhi, Tony, Wakelee, Heather A.
Published in Journal of clinical oncology (20.05.2016)

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Updated results from TIGER-X, a phase I/II open label study of rociletinib in patients (pts) with advanced, recurrent T790M-positive non-small cell lung cancer (NSCLC)

Updated results from TIGER-X, a phase I/II open label study of rociletinib in patients (pts) with advanced, recurrent T790M-positive non-small cell lung cancer (NSCLC)

by Goldman, Jonathan Wade, Soria, Jean-Charles, Wakelee, Heather A., Camidge, D. Ross, Gadgeel, Shirish M., Yu, Helena Alexandra, Reckamp, Karen L., Papadimitrakopoulou, Vassiliki, Perol, Maurice, Ou, Sai-Hong Ignatius, Matheny, Shannon L., Despain, Darrin, Isaacson, Jeffrey D., Yurasov, Sergey, Rolfe, Lindsey, Sequist, Lecia V.
Published in Journal of clinical oncology (20.05.2016)

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A phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors

A phase I/IIa study evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of lucitanib in advanced solid tumors

by Soria, Jean-Charles, De Braud, Filippo G., Bahleda, Ratislav, Adamo, Barbara, Cereda, Roberta, Camboni, Maria Gabriella, Robert, Renata, Isaacson, Jeffrey D., Litten, Jason B., Allen, Andrew R., Rolfe, Lindsey, Tabernero, Josep
Published in Journal of clinical oncology (20.05.2014)

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A phase I dose-escalation and PK study of continuous oral rucaparib in patients with advanced solid tumors

A phase I dose-escalation and PK study of continuous oral rucaparib in patients with advanced solid tumors

by Kristeleit, Rebecca Sophie, Shapiro, Geoffrey, LoRusso, Patricia, Infante, Jeffrey R., Flynn, Michael, Patel, Manish R., Tolaney, Sara M., Hilton, John Frederick, Calvert, Alan Hilary, Giordano, Heidi, Isaacson, Jeffrey D., Borrow, Jennifer, Allen, Andrew R., Jaw-Tsai, Sarah S., Burris, Howard A.
Published in Journal of clinical oncology (20.05.2013)

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Randomized multicenter, phase II study of CO-101 versus gemcitabine in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) and a prospective evaluation of the of the association between tumor hENT1 expression and clinical outcome with gemcitabine treatment

Randomized multicenter, phase II study of CO-101 versus gemcitabine in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) and a prospective evaluation of the of the association between tumor hENT1 expression and clinical outcome with gemcitabine treatment

by Poplin, Elizabeth, Wasan, Harpreet, Rolfe, Lindsey, Raponi, Mitch, Ikdahl, Tone, Bondarenko, Ihor, Davidenko, Irina, Bondar, Volodymyr, Garin, August, Boeck, Stefan Hubert, Heinemann, Volker, Bassi, Claudio, Evans, T. R. Jeffry, Voong, Cynthia, Kaur, Paramjit, Isaacson, Jeffrey D., Allen, Andrew R.
Published in Journal of clinical oncology (20.05.2013)

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