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A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial
Alton, Eric W F W, Boyd, A Christopher, Porteous, David J, Davies, Gwyneth, Davies, Jane C, Griesenbach, Uta, Higgins, Tracy E, Gill, Deborah R, Hyde, Stephen C, Innes, J Alastair
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Forced expiratory volume in one second predicts length of stay and in-hospital mortality in patients undergoing cardiac surgery: a retrospective cohort study
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Published in PloS one (28.05.2013)
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Sputum trace metals are biomarkers of inflammatory and suppurative lung disease
Gray, Robert D, Duncan, Andrew, Noble, Donald, Imrie, Margaret, O'Reilly, Dennis St J, Innes, J Alastair, Porteous, David J, Greening, Andrew P, Boyd, A Christopher
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Hypersensitivity pneumonitis associated with leflunomide therapy
Martin, Neil, Innes, J Alastair, Lambert, C Michael, Turnbull, Colin M, Wallace, William A H
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Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis
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Measurement of serum calprotectin in stable patients predicts exacerbation and lung function decline in cystic fibrosis
Reid, Philip A, McAllister, David A, Boyd, A Christopher, Innes, J Alastair, Porteous, David, Greening, Andrew P, Gray, Robert D
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Atopy Influences Exhaled Nitric Oxide Levels in Adult Asthmatics
Ho, Ling-Pei, Wood, Fraser T., Robson, Andrew, Innes, J. Alastair, Greening, Andrew P.
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Genetic medicines for CF: Hype versus reality
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Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy
GRIESENBACH, Uta, INOUE, Makoto, BOYD, A. Christopher, DAVIES, Jane C, HIGGINS, Tracy E, GILL, Deborah R, HYDE, Stephen C, INNES, J. Alastair, PORTEOUS, David J, HASEGAWA, Mamoru, ALTON, Eric W. F. W, CUIXIANG MENG, FARLEY, Raymond, CHAN, Mario, NEWMAN, Nikki K, BRUM, Andrea, JUN YOU, KERTON, Angela, SHOEMARK, Amelia
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A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis
Alton, Eric W F W, Boyd, A Christopher, Cheng, Seng H, Cunningham, Steve, Davies, Jane C, Gill, Deborah R, Griesenbach, Uta, Higgins, Tracy, Hyde, Stephen C, Innes, J Alastair, Murray, Gordon D, Porteous, David J
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Cardiopulmonary Exercise Testing Provides Prognostic Information in Advanced Cystic Fibrosis Lung Disease
Radtke, Thomas, Urquhart, Don S, Braun, Julia, Barry, Peter J, Waller, Ian, Petch, Nicole, Mei-Zahav, Meir, Kramer, Mordechai R, Hua-Huy, Thong, Dinh-Xuan, Anh Tuan, Innes, J Alastair, McArthur, Sara, Sovtic, Aleksandar, Gojsina, Bojana, Verges, Samuel, de Maat, Tanguy, Morrison, Lisa, Wood, Jamie, Crute, Samantha, Williams, Craig A, Tomlinson, Owen W, Bar-Yoseph, Ronen, Hebestreit, Alexandra, Quon, Bradley S, Kwong, Eugenie, Saynor, Zoe L, Causer, Adam J, Stephenson, Anne L, Schneiderman, Jane E, Shaw, Michelle, Dwyer, Tiffany, Stevens, Daniel, Remus, Natascha, Douvry, Benoit, Foster, Karla, Benden, Christian, Ratjen, Felix, Hebestreit, Helge
Published in Annals of the American Thoracic Society (01.03.2024)
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The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep
Alton, Eric W.F.W, Baker, Alison, Baker, Eilidh, Boyd, A. Christopher, Cheng, Seng H, Coles, Rebecca L, Collie, D. David S, Davidson, Heather, Davies, Jane C, Gill, Deborah R, Gordon, Catherine, Griesenbach, Uta, Higgins, Tracy, Hyde, Stephen C, Innes, J. Alastair, McCormick, Dominique, McGovern, Michael, McLachlan, Gerry, Porteous, David J, Pringle, Ian, Scheule, Ronald K, Shaw, Darren J, Smith, Sionagh, Sumner-Jones, Stephanie G, Tennant, Peter, Vrettou, Christina
Published in Biomaterials (01.12.2013)
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Effects of cystic fibrosis lung disease on gas mixing indices derived from alveolar slope analysis
Horsley, Alex R, Macleod, Kenneth A, Robson, Andrew G, Lenney, Jill, Bell, Nicholas J, Cunningham, Steve, Greening, Andrew P, Gustafsson, Per M, Innes, J. Alastair
Published in Respiratory physiology & neurobiology (31.08.2008)
Published in Respiratory physiology & neurobiology (31.08.2008)
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Biomarkers for cystic fibrosis lung disease: Application of SELDI-TOF mass spectrometry to BAL fluid
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Published in Journal of cystic fibrosis (01.09.2008)
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Self-reactive CFTR T cells in humans: implications for gene therapy
Calcedo, Roberto, Griesenbach, Uta, Dorgan, Daniel J, Soussi, Samia, Boyd, A Christopher, Davies, Jane C, Higgins, Tracy E, Hyde, Stephen C, Gill, Deborah R, Innes, J Alastair, Porteous, David J, Alton, Eric W, Wilson, James M, Limberis, Maria P
Published in Human gene therapy. Clinical development (01.09.2013)
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Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
Alton, Eric W F W, Armstrong, David K, Ashby, Deborah, Bayfield, Katie J, Bilton, Diana, Bloomfield, Emily V, Boyd, A Christopher, Brand, June, Buchan, Ruaridh, Calcedo, Roberto, Carvelli, Paula, Chan, Mario, Cheng, Seng H, Collie, D David S, Cunningham, Steve, Davidson, Heather E, Davies, Gwyneth, Davies, Jane C, Davies, Lee A, Dewar, Maria H, Doherty, Ann, Donovan, Jackie, Dwyer, Natalie S, Elgmati, Hala I, Featherstone, Rosanna F, Gavino, Jemyr, Gea-Sorli, Sabrina, Geddes, Duncan M, Gibson, James S R, Gill, Deborah R, Greening, Andrew P, Griesenbach, Uta, Hansell, David M, Harman, Katharine, Higgins, Tracy E, Hodges, Samantha L, Hyde, Stephen C, Hyndman, Laura, Innes, J Alastair, Jacob, Joseph, Jones, Nancy, Keogh, Brian F, Limberis, Maria P, Lloyd-Evans, Paul, Maclean, Alan W, Manvell, Michelle C, McCormick, Dominique, McGovern, Michael, McLachlan, Gerry, Meng, Cuixiang, Montero, M Angeles, Milligan, Hazel, Moyce, Laura J, Murray, Gordon D, Nicholson, Andrew G, Osadolor, Tina, Parra-Leiton, Javier, Porteous, David J, Pringle, Ian A, Punch, Emma K, Pytel, Kamila M, Quittner, Alexandra L, Rivellini, Gina, Saunders, Clare J, Scheule, Ronald K, Sheard, Sarah, Simmonds, Nicholas J, Smith, Keith, Smith, Stephen N, Soussi, Najwa, Soussi, Samia, Spearing, Emma J, Stevenson, Barbara J, Sumner-Jones, Stephanie G, Turkkila, Minna, Ureta, Rosa P, Waller, Michael D, Wasowicz, Marguerite Y, Wilson, James M, Wolstenholme-Hogg, Paul
Published in The lancet respiratory medicine (01.09.2015)
Published in The lancet respiratory medicine (01.09.2015)
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