The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database
Gaedigk, Andrea, Ingelman‐Sundberg, Magnus, Miller, Neil A., Leeder, J. Steven, Whirl‐Carrillo, Michelle, Klein, Teri E.
Published in Clinical pharmacology and therapeutics (01.03.2018)
Published in Clinical pharmacology and therapeutics (01.03.2018)
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Journal Article
Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics
Vorrink, Sabine U., Ullah, Shahid, Schmidt, Staffan, Nandania, Jatin, Velagapudi, Vidya, Beck, Olof, Ingelman‐Sundberg, Magnus, Lauschke, Volker M.
Published in The FASEB journal (01.06.2017)
Published in The FASEB journal (01.06.2017)
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Journal Article
3D human liver spheroids for translational pharmacology and toxicology
Ingelman‐Sundberg, Magnus, Lauschke, Volker M.
Published in Basic & clinical pharmacology & toxicology (01.01.2022)
Published in Basic & clinical pharmacology & toxicology (01.01.2022)
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Journal Article
How to Consider Rare Genetic Variants in Personalized Drug Therapy
Lauschke, Volker M, Ingelman-Sundberg, Magnus
Published in Clinical pharmacology and therapeutics (01.05.2018)
Published in Clinical pharmacology and therapeutics (01.05.2018)
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Journal Article
Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing
Wouden, Cathelijne H., van Rhenen, Mandy H., Jama, Wafa O.M., Ingelman‐Sundberg, Magnus, Lauschke, Volker M., Konta, Lidija, Schwab, Matthias, Swen, Jesse J., Guchelaar, Henk‐Jan
Published in Clinical pharmacology and therapeutics (01.10.2019)
Published in Clinical pharmacology and therapeutics (01.10.2019)
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Journal Article
Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes
Hendriks, Delilah F.G., Vorrink, Sabine U., Smutny, Tomas, Sim, Sarah C., Nordling, Åsa, Ullah, Shahid, Kumondai, Masaki, Jones, Barry C., Johansson, Inger, Andersson, Tommy B., Lauschke, Volker M., Ingelman‐Sundberg, Magnus
Published in Clinical pharmacology and therapeutics (01.10.2020)
Published in Clinical pharmacology and therapeutics (01.10.2020)
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Journal Article
Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation
Lauschke, Volker M., Vorrink, Sabine U., Moro, Sabrina M.L., Rezayee, Fatemah, Nordling, Åsa, Hendriks, Delilah F.G., Bell, Catherine C., Sison‐Young, Rowena, Park, B. Kevin, Goldring, Christopher E., Ellis, Ewa, Johansson, Inger, Mkrtchian, Souren, Andersson, Tommy B., Ingelman‐Sundberg, Magnus
Published in Hepatology (Baltimore, Md.) (01.11.2016)
Published in Hepatology (Baltimore, Md.) (01.11.2016)
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Journal Article
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism
Smutny, Tomas, Hyrsova, Lucie, Braeuning, Albert, Ingelman-Sundberg, Magnus, Pavek, Petr
Published in Archives of toxicology (01.01.2021)
Published in Archives of toxicology (01.01.2021)
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Journal Article
Stem cell–derived models to improve mechanistic understanding and prediction of human drug‐induced liver injury
Goldring, Christopher, Antoine, Daniel J., Bonner, Frank, Crozier, Jonathan, Denning, Chris, Fontana, Robert J., Hanley, Neil A., Hay, David C., Ingelman‐Sundberg, Magnus, Juhila, Satu, Kitteringham, Neil, Silva‐Lima, Beatriz, Norris, Alan, Pridgeon, Chris, Ross, James A., Young, Rowena Sison, Tagle, Danilo, Tornesi, Belen, van de Water, Bob, Weaver, Richard J., Zhang, Fang, Park, B. Kevin
Published in Hepatology (Baltimore, Md.) (01.02.2017)
Published in Hepatology (Baltimore, Md.) (01.02.2017)
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Journal Article
Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population
Bråten, Line Skute, Ingelman‐Sundberg, Magnus, Jukic, Marin M., Molden, Espen, Kringen, Marianne Kristiansen
Published in Clinical and translational science (01.09.2022)
Published in Clinical and translational science (01.09.2022)
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Journal Article
Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man
Dragovic, Sanja, Vermeulen, Nico P. E., Gerets, Helga H., Hewitt, Philip G., Ingelman‐Sundberg, Magnus, Park, B. Kevin, Juhila, Satu, Snoeys, Jan, Weaver, Richard J.
Published in Archives of toxicology (01.12.2016)
Published in Archives of toxicology (01.12.2016)
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Journal Article
The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia
Milosavljević, Filip, Brusini, Irene, Atanasov, Andrea, Manojlović, Marina, Vučić, Marija, Oreščanin‐Dušić, Zorana, Brkljačić, Jelena, Miljević, Čedo, Nikolić‐Kokić, Aleksandra, Blagojević, Duško, Wang, Chunliang, Damberg, Peter, Pešić, Vesna, Tyndale, Rachel F., Ingelman‐Sundberg, Magnus, Jukić, Marin M.
Published in Neuropathology and applied neurobiology (01.02.2023)
Published in Neuropathology and applied neurobiology (01.02.2023)
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Journal Article
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine
Smith, Robert Løvsletten, Wollmann, Birgit M., Størset, Elisabet, Lenk, Hasan Çağın, O'Connell, Kevin S., Kristiansen, Marianne Kringen, Ingelman‐Sundberg, Magnus, Molden, Espen
Published in Clinical and translational science (01.02.2024)
Published in Clinical and translational science (01.02.2024)
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Journal Article
Increased omeprazole metabolism in carriers of the CYP2C1917 allele; a pharmacokinetic study in healthy volunteers
Baldwin, R. Michael, Ohlsson, Staffan, Pedersen, Rasmus Steen, Mwinyi, Jessica, Ingelman‐Sundberg, Magnus, Eliasson, Erik, Bertilsson, Leif
Published in British journal of clinical pharmacology (01.05.2008)
Published in British journal of clinical pharmacology (01.05.2008)
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Journal Article
Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits
Lenk, Hasan Çağın, Løvsletten Smith, Robert, O'Connell, Kevin S., Jukić, Marin M., Kringen, Marianne Kristiansen, Andreassen, Ole A., Ingelman‐Sundberg, Magnus, Molden, Espen
Published in Clinical and translational science (01.01.2023)
Published in Clinical and translational science (01.01.2023)
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Journal Article
Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials
Milosavljević, Filip, Molden, Prof. Espen, Ingelman-Sundberg, Prof. Magnus, Jukić, Assoc. Prof. Marin M
Published in European neuropsychopharmacology (01.04.2024)
Published in European neuropsychopharmacology (01.04.2024)
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Journal Article
High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis
Edsbagge, Josefina, Johansson, Inger, Sartipy, Peter, Ingelman-Sundberg, Magnus, Holmgren, Gustav, Jacobsson, Susanna, Steel, Daniella, Pradip, Arvind, Björquist, Petter
Published in Stem Cells International (01.01.2016)
Published in Stem Cells International (01.01.2016)
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Journal Article