Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma
Péneau, Camille, Imbeaud, Sandrine, La Bella, Tiziana, Hirsch, Theo Z, Caruso, Stefano, Calderaro, Julien, Paradis, Valerie, Blanc, Jean-Frederic, Letouzé, Eric, Nault, Jean-Charles, Amaddeo, Giuliana, Zucman-Rossi, Jessica
Published in Gut (01.03.2022)
Published in Gut (01.03.2022)
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Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
Schulze, Kornelius, Imbeaud, Sandrine, Letouzé, Eric, Alexandrov, Ludmil B, Calderaro, Julien, Rebouissou, Sandra, Couchy, Gabrielle, Meiller, Clément, Shinde, Jayendra, Soysouvanh, Frederic, Calatayud, Anna-Line, Pinyol, Roser, Pelletier, Laura, Balabaud, Charles, Laurent, Alexis, Blanc, Jean-Frederic, Mazzaferro, Vincenzo, Calvo, Fabien, Villanueva, Augusto, Nault, Jean-Charles, Bioulac-Sage, Paulette, Stratton, Michael R, Llovet, Josep M, Zucman-Rossi, Jessica
Published in Nature genetics (01.05.2015)
Published in Nature genetics (01.05.2015)
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Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas
Nault, Jean-Charles, Datta, Shalini, Imbeaud, Sandrine, Franconi, Andrea, Mallet, Maxime, Couchy, Gabrielle, Letouzé, Eric, Pilati, Camilla, Verret, Benjamin, Blanc, Jean-Frédéric, Balabaud, Charles, Calderaro, Julien, Laurent, Alexis, Letexier, Mélanie, Bioulac-Sage, Paulette, Calvo, Fabien, Zucman-Rossi, Jessica
Published in Nature genetics (01.10.2015)
Published in Nature genetics (01.10.2015)
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Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
Letouzé, Eric, Shinde, Jayendra, Renault, Victor, Couchy, Gabrielle, Blanc, Jean-Frédéric, Tubacher, Emmanuel, Bayard, Quentin, Bacq, Delphine, Meyer, Vincent, Semhoun, Jérémy, Bioulac-Sage, Paulette, Prévôt, Sophie, Azoulay, Daniel, Paradis, Valérie, Imbeaud, Sandrine, Deleuze, Jean-François, Zucman-Rossi, Jessica
Published in Nature communications (03.11.2017)
Published in Nature communications (03.11.2017)
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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
Guichard, Cécile, Amaddeo, Giuliana, Imbeaud, Sandrine, Ladeiro, Yannick, Pelletier, Laura, Maad, Ichrafe Ben, Calderaro, Julien, Bioulac-Sage, Paulette, Letexier, Mélanie, Degos, Françoise, Clément, Bruno, Balabaud, Charles, Chevet, Eric, Laurent, Alexis, Couchy, Gabrielle, Letouzé, Eric, Calvo, Fabien, Zucman-Rossi, Jessica
Published in Nature genetics (01.06.2012)
Published in Nature genetics (01.06.2012)
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DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma
Villanueva, Augusto, Portela, Anna, Sayols, Sergi, Battiston, Carlo, Hoshida, Yujin, Méndez‐González, Jesús, Imbeaud, Sandrine, Letouzé, Eric, Hernandez‐Gea, Virginia, Cornella, Helena, Pinyol, Roser, Solé, Manel, Fuster, Josep, Zucman‐Rossi, Jessica, Mazzaferro, Vincenzo, Esteller, Manel, Llovet, Josep M.
Published in Hepatology (Baltimore, Md.) (01.06.2015)
Published in Hepatology (Baltimore, Md.) (01.06.2015)
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Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma
Nault, Jean‐Charles, Martin, Yoann, Caruso, Stefano, Hirsch, Théo Z., Bayard, Quentin, Calderaro, Julien, Charpy, Cecile, Copie‐Bergman, Christiane, Ziol, Marianne, Bioulac‐Sage, Paulette, Couchy, Gabrielle, Blanc, Jean‐Frédéric, Nahon, Pierre, Amaddeo, Giuliana, Ganne‐Carrie, Nathalie, Morcrette, Guillaume, Chiche, Laurence, Duvoux, Christophe, Faivre, Sandrine, Laurent, Alexis, Imbeaud, Sandrine, Rebouissou, Sandra, Llovet, Josep M., Seror, Olivier, Letouzé, Eric, Zucman‐Rossi, Jessica
Published in Hepatology (Baltimore, Md.) (01.01.2020)
Published in Hepatology (Baltimore, Md.) (01.01.2020)
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A 17‐Beta‐Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease
Yang, Jie, Trépo, Eric, Nahon, Pierre, Cao, Qian, Moreno, Christophe, Letouzé, Eric, Imbeaud, Sandrine, Bayard, Quentin, Gustot, Thierry, Deviere, Jacques, Bioulac‐Sage, Paulette, Calderaro, Julien, Ganne‐Carrié, Nathalie, Laurent, Alexis, Blanc, Jean Frédéric, Guyot, Erwan, Sutton, Angela, Ziol, Marianne, Zucman‐Rossi, Jessica, Nault, Jean‐Charles
Published in Hepatology (Baltimore, Md.) (01.07.2019)
Published in Hepatology (Baltimore, Md.) (01.07.2019)
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Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classification
Beyoğlu, Diren, Imbeaud, Sandrine, Maurhofer, Olivier, Bioulac‐Sage, Paulette, Zucman‐Rossi, Jessica, Dufour, Jean‐François, Idle, Jeffrey R.
Published in Hepatology (Baltimore, Md.) (01.07.2013)
Published in Hepatology (Baltimore, Md.) (01.07.2013)
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Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress
Bayard, Quentin, Meunier, Léa, Peneau, Camille, Renault, Victor, Shinde, Jayendra, Nault, Jean-Charles, Mami, Iadh, Couchy, Gabrielle, Amaddeo, Giuliana, Tubacher, Emmanuel, Bacq, Delphine, Meyer, Vincent, La Bella, Tiziana, Debaillon-Vesque, Audrey, Bioulac-Sage, Paulette, Seror, Olivier, Blanc, Jean-Frédéric, Calderaro, Julien, Deleuze, Jean-François, Imbeaud, Sandrine, Zucman-Rossi, Jessica, Letouzé, Eric
Published in Nature communications (07.12.2018)
Published in Nature communications (07.12.2018)
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Genomic Profiling of Hepatocellular Adenomas Reveals Recurrent FRK-Activating Mutations and the Mechanisms of Malignant Transformation
Pilati, Camilla, Letouzé, Eric, Nault, Jean-Charles, Imbeaud, Sandrine, Boulai, Anaïs, Calderaro, Julien, Poussin, Karine, Franconi, Andrea, Couchy, Gabrielle, Morcrette, Guillaume, Mallet, Maxime, Taouji, Saïd, Balabaud, Charles, Terris, Benoit, Canal, Frédéric, Paradis, Valérie, Scoazec, Jean-Yves, de Muret, Anne, Guettier, Catherine, Bioulac-Sage, Paulette, Chevet, Eric, Calvo, Fabien, Zucman-Rossi, Jessica
Published in Cancer cell (14.04.2014)
Published in Cancer cell (14.04.2014)
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PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases
Yang, Jie, Trépo, Eric, Nahon, Pierre, Cao, Qian, Moreno, Christophe, Letouzé, Eric, Imbeaud, Sandrine, Gustot, Thierry, Deviere, Jacques, Debette, Stéphanie, Amouyel, Philippe, Bioulac‐Sage, Paulette, Calderaro, Julien, Ganne‐Carrié, Nathalie, Laurent, Alexis, Blanc, Jean Frédéric, Guyot, Erwan, Sutton, Angela, Ziol, Marianne, Zucman‐Rossi, Jessica, Nault, Jean‐Charles
Published in International journal of cancer (01.02.2019)
Published in International journal of cancer (01.02.2019)
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Global analysis of extracytoplasmic stress signaling in Escherichia coli
Bury-Moné, Stéphanie, Nomane, Yanoura, Reymond, Nancie, Barbet, Romain, Jacquet, Eric, Imbeaud, Sandrine, Jacq, Annick, Bouloc, Philippe
Published in PLoS genetics (01.09.2009)
Published in PLoS genetics (01.09.2009)
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Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry
Bioulac‐Sage, Paulette, Rebouissou, Sandra, Thomas, Cristel, Blanc, Jean‐Frédéric, Saric, Jean, Sa Cunha, Antonio, Rullier, Anne, Cubel, Gaëlle, Couchy, Gabrielle, Imbeaud, Sandrine, Balabaud, Charles, Zucman‐Rossi, Jessica
Published in Hepatology (Baltimore, Md.) (01.09.2007)
Published in Hepatology (Baltimore, Md.) (01.09.2007)
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DNA Methylation Signatures Reveal the Diversity of Processes Remodeling Hepatocellular Carcinoma Methylomes
Meunier, Léa, Hirsch, Théo Z., Caruso, Stefano, Imbeaud, Sandrine, Bayard, Quentin, Roehrig, Amélie, Couchy, Gabrielle, Nault, Jean‐Charles, Llovet, Josep M., Blanc, Jean‐Frédéric, Calderaro, Julien, Zucman‐Rossi, Jessica, Letouzé, Eric
Published in Hepatology (Baltimore, Md.) (01.08.2021)
Published in Hepatology (Baltimore, Md.) (01.08.2021)
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Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival
Quetel, Lisa, Meiller, Clément, Assié, Jean‐Baptiste, Blum, Yuna, Imbeaud, Sandrine, Montagne, François, Tranchant, Robin, Wolf, Julien, Caruso, Stefano, Copin, Marie‐Christine, Hofman, Véronique, Gibault, Laure, Badoual, Cécile, Pintilie, Ecaterina, Hofman, Paul, Monnet, Isabelle, Scherpereel, Arnaud, Le Pimpec‐Barthes, Françoise, Zucman‐Rossi, Jessica, Jaurand, Marie‐Claude, Jean, Didier
Published in Molecular oncology (01.06.2020)
Published in Molecular oncology (01.06.2020)
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Proliferation Markers Are Associated with MET Expression in Hepatocellular Carcinoma and Predict Tivantinib Sensitivity In Vitro
Rebouissou, Sandra, La Bella, Tiziana, Rekik, Samia, Imbeaud, Sandrine, Calatayud, Anna-Line, Rohr-Udilova, Nataliya, Martin, Yoann, Couchy, Gabrielle, Bioulac-Sage, Paulette, Grasl-Kraupp, Bettina, de Koning, Leanne, Ganne-Carrié, Nathalie, Nault, Jean-Charles, Ziol, Marianne, Zucman-Rossi, Jessica
Published in Clinical cancer research (01.08.2017)
Published in Clinical cancer research (01.08.2017)
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Single-cell multiomics reveals the interplay of clonal evolution and cellular plasticity in hepatoblastoma
Roehrig, Amélie, Hirsch, Theo Z., Pire, Aurore, Morcrette, Guillaume, Gupta, Barkha, Marcaillou, Charles, Imbeaud, Sandrine, Chardot, Christophe, Gonzales, Emmanuel, Jacquemin, Emmanuel, Sekiguchi, Masahiro, Takita, Junko, Nagae, Genta, Hiyama, Eiso, Guérin, Florent, Fabre, Monique, Aerts, Isabelle, Taque, Sophie, Laithier, Véronique, Branchereau, Sophie, Guettier, Catherine, Brugières, Laurence, Fresneau, Brice, Zucman-Rossi, Jessica, Letouzé, Eric
Published in Nature communications (08.04.2024)
Published in Nature communications (08.04.2024)
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Molecular Classification of Malignant Pleural Mesothelioma: Identification of a Poor Prognosis Subgroup Linked to the Epithelial-to-Mesenchymal Transition
DE REYNIES, Aurélien, JAURAND, Marie-Claude, ANDUJAR, Pascal, IMBEAUD, Sandrine, PETEL, Fabien, PAIRON, Jean-Claude, LE PIMPEC-BATRHES, Francoise, ZUCMAN-ROSSI, Jessica, JEAN, Didier, RENIER, Annie, COUCHY, Gabrielle, HYSI, Ilir, ELAROUCI, Nabila, GALATEAU-SALLE, Franpoise, COPIN, Marie-Christine, HOFMAN, Paul, CAZES, Aurélie
Published in Clinical cancer research (01.03.2014)
Published in Clinical cancer research (01.03.2014)
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Epithelial-to-Mesenchymal Transition and MicroRNAs in Lung Cancer
Legras, Antoine, Pécuchet, Nicolas, Imbeaud, Sandrine, Pallier, Karine, Didelot, Audrey, Roussel, Hélène, Gibault, Laure, Fabre, Elizabeth, Le Pimpec-Barthes, Françoise, Laurent-Puig, Pierre, Blons, Hélène
Published in Cancers (03.08.2017)
Published in Cancers (03.08.2017)
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