Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma
Choi, Jiyeon, Zhang, Tongwu, Vu, Andrew, Ablain, Julien, Makowski, Matthew M., Colli, Leandro M., Xu, Mai, Hennessey, Rebecca C., Yin, Jinhu, Rothschild, Harriet, Gräwe, Cathrin, Kovacs, Michael A., Funderburk, Karen M., Brossard, Myriam, Taylor, John, Pasaniuc, Bogdan, Chari, Raj, Chanock, Stephen J., Hoggart, Clive J., Demenais, Florence, Barrett, Jennifer H., Law, Matthew H., Iles, Mark M., Yu, Kai, Vermeulen, Michiel, Zon, Leonard I., Brown, Kevin M.
Published in Nature communications (01.06.2020)
Published in Nature communications (01.06.2020)
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Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
Visconti, Alessia, Duffy, David L., Liu, Fan, Zhu, Gu, Wu, Wenting, Chen, Yan, Hysi, Pirro G., Zeng, Changqing, Sanna, Marianna, Iles, Mark M., Kanetsky, Peter A., Demenais, Florence, Hamer, Merel A., Uitterlinden, Andre G., Ikram, M. Arfan, Nijsten, Tamar, Martin, Nicholas G., Kayser, Manfred, Spector, Tim D., Han, Jiali, Bataille, Veronique, Falchi, Mario
Published in Nature communications (08.05.2018)
Published in Nature communications (08.05.2018)
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Genomewide Association Analysis of Coronary Artery Disease
Samani, Nilesh J, Erdmann, Jeanette, Hall, Alistair S, Hengstenberg, Christian, Mangino, Massimo, Mayer, Bjoern, Dixon, Richard J, Meitinger, Thomas, Braund, Peter, Wichmann, H.-Erich, Barrett, Jennifer H, König, Inke R, Stevens, Suzanne E, Szymczak, Silke, Tregouet, David-Alexandre, Iles, Mark M, Pahlke, Friedrich, Pollard, Helen, Lieb, Wolfgang, Cambien, Francois, Fischer, Marcus, Ouwehand, Willem, Blankenberg, Stefan, Balmforth, Anthony J, Baessler, Andrea, Ball, Stephen G, Strom, Tim M, Brænne, Ingrid, Gieger, Christian, Deloukas, Panos, Tobin, Martin D, Ziegler, Andreas, Thompson, John R, Schunkert, Heribert
Published in The New England journal of medicine (02.08.2007)
Published in The New England journal of medicine (02.08.2007)
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Fine-scale population structure and demographic history of British Pakistanis
Arciero, Elena, Dogra, Sufyan A., Malawsky, Daniel S., Mezzavilla, Massimo, Tsismentzoglou, Theofanis, Huang, Qin Qin, Hunt, Karen A., Mason, Dan, Sharif, Saghira Malik, van Heel, David A., Sheridan, Eamonn, Wright, John, Small, Neil, Carmi, Shai, Iles, Mark M., Martin, Hilary C.
Published in Nature communications (10.12.2021)
Published in Nature communications (10.12.2021)
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Genetic variants for smoking behaviour and risk of skin cancer
Dusingize, Jean Claude, Law, Matthew H., Seviiri, Mathias, Olsen, Catherine M., Pandeya, Nirmala, Landi, Maria Teresa, Iles, Mark M., Neale, Rachel E., Ong, Jue-Sheng, MacGregor, Stuart, Whiteman, David C.
Published in Scientific reports (06.10.2023)
Published in Scientific reports (06.10.2023)
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An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations
Simonin-Wilmer, Irving, Orozco-Del-Pino, Pedro, Bishop, D Timothy, Iles, Mark M, Robles-Espinoza, Carla Daniela
Published in Frontiers in genetics (05.11.2021)
Published in Frontiers in genetics (05.11.2021)
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Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort
Fuller, Harriett, Iles, Mark M, Moore, J Bernadette, Zulyniak, Michael A
Published in Frontiers in endocrinology (Lausanne) (15.05.2023)
Published in Frontiers in endocrinology (Lausanne) (15.05.2023)
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Uncovering the complex relationship between balding, testosterone and skin cancers in men
Ong, Jue-Sheng, Seviiri, Mathias, Dusingize, Jean Claude, Wu, Yeda, Han, Xikun, Shi, Jianxin, Olsen, Catherine M., Neale, Rachel E., Thompson, John F., Saw, Robyn P. M., Shannon, Kerwin F., Mann, Graham J., Martin, Nicholas G., Medland, Sarah E., Gordon, Scott D., Scolyer, Richard A., Long, Georgina V., Iles, Mark M., Landi, Maria Teresa, Whiteman, David C., MacGregor, Stuart, Law, Matthew H.
Published in Nature communications (03.10.2023)
Published in Nature communications (03.10.2023)
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Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting
Seviiri, Mathias, Scolyer, Richard A, Bishop, D Timothy, Newton-Bishop, Julia A, Iles, Mark M, Lo, Serigne N, Stretch, Johnathan R, Saw, Robyn P M, Nieweg, Omgo E, Shannon, Kerwin F, Spillane, Andrew J, Gordon, Scott D, Olsen, Catherine M, Whiteman, David C, Landi, Maria Teresa, Thompson, John F, Long, Georgina V, MacGregor, Stuart, Law, Matthew H
Published in Journal of translational medicine (05.09.2022)
Published in Journal of translational medicine (05.09.2022)
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Genetic Relationship Between Endometriosis and Melanoma
Yang, Fei, Mortlock, Sally, MacGregor, Stuart, Iles, Mark M., Landi, Maria Teresa, Shi, Jianxin, Law, Matthew H., Montgomery, Grant W.
Published in Frontiers in reproductive health (02.08.2021)
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Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals
Chen, Hongjie, Majumdar, Arunabha, Wang, Lu, Kar, Siddhartha, Brown, Kevin M., Feng, Helian, Turman, Constance, Dennis, Joe, Easton, Douglas, Michailidou, Kyriaki, Simard, Jacques, Bishop, Timothy, Cheng, Iona C., Huyghe, Jeroen R., Schmit, Stephanie L., O’Mara, Tracy A., Spurdle, Amanda B., Gharahkhani, Puya, Schumacher, Johannes, Jankowski, Janusz, Gockel, Ines, Bondy, Melissa L., Houlston, Richard S., Jenkins, Robert B., Melin, Beatrice, Lesseur, Corina, Ness, Andy R., Diergaarde, Brenda, Olshan, Andrew F., Amos, Christopher I., Christiani, David C., Landi, Maria T., McKay, James D., Brossard, Myriam, Iles, Mark M., Law, Matthew H., MacGregor, Stuart, Beesley, Jonathan, Jones, Michelle R., Tyrer, Jonathan, Winham, Stacey J., Klein, Alison P., Petersen, Gloria, Li, Donghui, Wolpin, Brian M., Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Brennan, Paul, Chanock, Stephen J., Gaborieau, Valerie, Purdue, Mark P., Pharoah, Paul, Hung, Rayjean J., Amundadottir, Laufey T., Kraft, Peter, Pasaniuc, Bogdan, Lindström, Sara
Published in HGG advances (08.07.2021)
Published in HGG advances (08.07.2021)
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Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility
Low, Yen Ling, Li, Yuqing, Humphreys, Keith, Thalamuthu, Anbupalam, Li, Yi, Darabi, Hatef, Wedrén, Sara, Bonnard, Carine, Czene, Kamila, Iles, Mark M, Heikkinen, Tuomas, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli, Hall, Per, Liu, Edison T, Liu, Jianjun
Published in PLoS genetics (01.07.2010)
Published in PLoS genetics (01.07.2010)
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Telomere length and common disease: study design and analytical challenges
Barrett, Jennifer H., Iles, Mark M., Dunning, Alison M., Pooley, Karen A.
Published in Human genetics (01.07.2015)
Published in Human genetics (01.07.2015)
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Yingchang, Gustafsson, Stefan, Cousminer, Diana L., Evans, David M., Ferreira, Teresa, Hedman, Åsa K., Haring, Robin, Iles, Mark M., Kanoni, Stavroula, Li, Rui, Sanna, Marianna, Scott, William R., Teumer, Alexander, Vinkhuyzen, Anna A. E., Westra, Harm-Jan, Zhang, Weihua, Zhu, Zhihong, Bakker, Stephan J. L., Borodulin, Katja, Buchman, Aron S., Choi, Hyung Jin, Curran, Joanne E., Dhonukshe-Rutten, Rosalie A. M., Enneman, Anke W., Eury, Elodie, Fumeron, Frédéric, Garcia, Melissa E., Havulinna, Aki S., Hayward, Caroline, Hernandez, Dena, Ittermann, Till, Lahti, Jari, Leach, Irene Mateo, Lobbens, Stéphane, Lyytikäinen, Leo-Pekka, Nalls, Mike A., Oozageer, Laticia, Sarzynski, Mark A., Narančić, Nina Smolej, Spira, Dominik, Srikanth, Priya, Sung, Yun Ju, Tanaka, Toshiko, Wright, Alan F., Lichtner, Peter, Luan, Jian'an, Mahajan, Anubha, Palmer, Cameron D., Ried, Janina S., Mcknight, Barbara, Menni, Cristina, Oostra, Ben A., Song, Kijoung, Forouhi, Nita G., Grallert, Harald, Hingorani, Aroon, Jousilahti, Pekka, Laakso, Markku, Linneberg, Allan, Luke, Amy, Palotie, Aarno, Tayo, Bamidele O., Bennett, David A., Blüher, Matthias, Bouchard, Claude, Demuth, Ilja, Ferrucci, Luigi, Franco, Oscar H., Harris, Tamara B., Heliövaara, Markku, Jordan, Joanne M., Knekt, Paul B., Koskinen, Seppo, Kovacs, Peter, Liu, Yongmei, Orwoll, Eric S., Osmond, Clive, Rudan, Igor, Stumvoll, Michael, Tönjes, Anke, Towne, Bradford, Tranah, Gregory J., Uitterlinden, André G., Vohl, Marie-Claude, Walker, Mark, Wild, Sarah, Bishop, D. Timothy, Borecki, Ingrid B., Chambers, John C., Cupples, L. Adrienne, Han, Jiali, Morris, Andrew P., Bishop, Julia A. N., Ohlsson, Claes, Ong, Ken K., Spector, Tim D., Willer, Cristen J., Yang, Jian, Hirschhorn, Joel N., Zillikens, M. Carola
Published in Nature communications (01.02.2016)
Published in Nature communications (01.02.2016)
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Analysis of variants in DNA damage signalling genes in bladder cancer
Choudhury, Ananya, Elliott, Faye, Iles, Mark M, Churchman, Michael, Bristow, Robert G, Bishop, D Timothy, Kiltie, Anne E
Published in BMC medical genetics (18.07.2008)
Published in BMC medical genetics (18.07.2008)
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Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers
Zhang, Yan Dora, Hurson, Amber N., Zhang, Haoyu, Choudhury, Parichoy Pal, Easton, Douglas F., Milne, Roger L., Simard, Jacques, Hall, Per, Michailidou, Kyriaki, Dennis, Joe, Schmidt, Marjanka K., Chang-Claude, Jenny, Gharahkhani, Puya, Whiteman, David, Campbell, Peter T., Hoffmeister, Michael, Jenkins, Mark, Peters, Ulrike, Hsu, Li, Gruber, Stephen B., Casey, Graham, Schmit, Stephanie L., O’Mara, Tracy A., Spurdle, Amanda B., Thompson, Deborah J., Tomlinson, Ian, De Vivo, Immaculata, Landi, Maria Teresa, Law, Matthew H., Iles, Mark M., Demenais, Florence, Kumar, Rajiv, MacGregor, Stuart, Bishop, D. Timothy, Ward, Sarah V., Bondy, Melissa L., Houlston, Richard, Wiencke, John K., Melin, Beatrice, Barnholtz-Sloan, Jill, Kinnersley, Ben, Wrensch, Margaret R., Amos, Christopher I., Hung, Rayjean J., Brennan, Paul, McKay, James, Caporaso, Neil E., Berndt, Sonja I., Birmann, Brenda M., Camp, Nicola J., Kraft, Peter, Rothman, Nathaniel, Slager, Susan L., Berchuck, Andrew, Pharoah, Paul D. P., Sellers, Thomas A., Gayther, Simon A., Pearce, Celeste L., Goode, Ellen L., Schildkraut, Joellen M., Moysich, Kirsten B., Amundadottir, Laufey T., Jacobs, Eric J., Klein, Alison P., Petersen, Gloria M., Risch, Harvey A., Stolzenberg-Solomon, Rachel Z., Wolpin, Brian M., Li, Donghui, Eeles, Rosalind A., Haiman, Christopher A., Kote-Jarai, Zsofia, Schumacher, Fredrick R., Al Olama, Ali Amin, Purdue, Mark P., Scelo, Ghislaine, Dalgaard, Marlene D., Greene, Mark H., Grotmol, Tom, Kanetsky, Peter A., McGlynn, Katherine A., Nathanson, Katherine L., Turnbull, Clare, Wiklund, Fredrik, Chanock, Stephen J., Chatterjee, Nilanjan, Garcia-Closas, Montserrat
Published in Nature communications (03.07.2020)
Published in Nature communications (03.07.2020)
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