ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex
Park, Kyungho, Ikushiro, Hiroko, Seo, Ho Seong, Shin, Kyong-Oh, Kim, Young il, Kim, Jong Youl, Lee, Yong-Moon, Yano, Takato, Holleran, Walter M., Elias, Peter, Uchida, Yoshikazu
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2016)
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Journal Article
Heme-dependent Inactivation of 5-Aminolevulinate Synthase from Caulobacter crescentus
Ikushiro, Hiroko, Nagami, Atsushi, Takai, Tomoko, Sawai, Taiki, Shimeno, Yuki, Hori, Hiroshi, Miyahara, Ikuko, Kamiya, Nobuo, Yano, Takato
Published in Scientific reports (21.09.2018)
Published in Scientific reports (21.09.2018)
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Journal Article
Role of a conserved arginine residue during catalysis in serine palmitoyltransferase
Lowther, Jonathan, Charmier, Guillaume, Raman, Marine C., Ikushiro, Hiroko, Hayashi, Hideyuki, Campopiano, Dominic J.
Published in FEBS letters (23.06.2011)
Published in FEBS letters (23.06.2011)
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Journal Article
Multifunctional Role of His159in the Catalytic Reaction of Serine Palmitoyltransferase
Shiraiwa, Yuka, Ikushiro, Hiroko, Hayashi, Hideyuki
Published in The Journal of biological chemistry (05.06.2009)
Published in The Journal of biological chemistry (05.06.2009)
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Journal Article
Structural and kinetic study on bacterial serine palmitoyltransferase
Ikushiro, Hiroko, Hayashi, Hideyuki
Published in Seikagaku. The Journal of Japanese Biochemical Society (01.02.2011)
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Published in Seikagaku. The Journal of Japanese Biochemical Society (01.02.2011)
Journal Article
Binding of C5-Dicarboxylic Substrate to Aspartate Aminotransferase: Implications for the Conformational Change at the Transaldimination Step
Islam, Mohammad Mainul, Goto, Masaru, Miyahara, Ikuko, Ikushiro, Hiroko, Hirotsu, Ken, Hayashi, Hideyuki
Published in Biochemistry (Easton) (14.06.2005)
Published in Biochemistry (Easton) (14.06.2005)
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Journal Article
Strain and catalysis in aspartate aminotransferase
Hayashi, Hideyuki, Mizuguchi, Hiroyuki, Miyahara, Ikuko, Islam, Mohammad Mainul, Ikushiro, Hiroko, Nakajima, Yoshitaka, Hirotsu, Ken, Kagamiyama, Hiroyuki
Published in BBA - Proteins and Proteomics (11.04.2003)
Published in BBA - Proteins and Proteomics (11.04.2003)
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Book Review
Journal Article
Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum
Ikushiro, Hiroko, Murakami, Taiki, Takahashi, Aya, Katayama, Asuka, Sawai, Taiki, Goto, Haruna, Koolath, Sajeer, Murai, Yuta, Monde, Kenji, Miyahara, Ikuko, Kamiya, Nobuo, Yano, Takato
Published in The Journal of biological chemistry (01.05.2023)
Published in The Journal of biological chemistry (01.05.2023)
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Journal Article
Racemization of the substrate and product by serine palmitoyltransferase from Sphingobacterium multivorum yields two enantiomers of the product from d-serine
Ikushiro, Hiroko, Honda, Takumi, Murai, Yuta, Murakami, Taiki, Takahashi, Aya, Sawai, Taiki, Goto, Haruna, Ikushiro, Shin-ichi, Miyahara, Ikuko, Hirabayashi, Yoshio, Kamiya, Nobuo, Monde, Kenji, Yano, Takato
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Crystal structure of Sphingobacterium multivorum serine palmitoyltransferase complexed with tris(hydroxymethyl)aminomethane
Ikushiro, Hiroko, Takahashi, Aya, Murakami, Taiki, Katayama, Asuka, Sawai, Taiki, Goto, Haruna, Miyahara, Ikuko, Kamiya, Nobuo, Yano, Takato
Published in Acta crystallographica. Section F, Structural biology communications (01.12.2022)
Published in Acta crystallographica. Section F, Structural biology communications (01.12.2022)
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Journal Article
Both Sphingosine Kinase 1 and 2 Coordinately Regulate Cathelicidin Antimicrobial Peptide Production during Keratinocyte Differentiation
Shin, Kyong-Oh, Kim, Kun Pyo, Cho, Yunhi, Kang, Min-Kyung, Kang, Young-Hee, Lee, Yong-Moon, Ikushiro, Hiroko, Yokota, Mami, Yano, Takato, Choe, Sung Jay, Choi, Eung Ho, Lim, Chae Jin, Park, Keedon, Holleran, Walter M., Park, Kyungho, Uchida, Yoshikazu
Published in Journal of investigative dermatology (01.02.2019)
Published in Journal of investigative dermatology (01.02.2019)
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Journal Article
ER stress and S1P orchestrate a novel stress-specific signals to stimulate cathelicidin antimicrobial peptide production
Park, Kyungho, Ikushiro, Hiroko, Seo, Ho Seong, Shin, Kyong-Oh, Kim, Young il, Lee, Yong-Moon, Yano, Takato, Holleran, Walter M, Elias, Peter M, Uchida, Yoshikazu
Published in Journal of dermatological science (01.05.2017)
Published in Journal of dermatological science (01.05.2017)
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Journal Article