Interruption of mitochondrial complex IV activity and cytochrome c expression activated O·―2-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R―PI3K―Akt and IGF-1R―PLC γ―PKC pathways
JIANG, Yuan-Yuan, HUAI HUANG, WANG, Hong-Jun, DI WU, RI YANG, TASHIRO, Shin-Ichi, ONODERA, Satoshi, IKEJIMA, Takashi
Published in European journal of pharmacology (01.10.2011)
Published in European journal of pharmacology (01.10.2011)
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In vivo recovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of sirt-1 expression and autophagy in pancreatic [beta]-cell
Wang, Qiong, Liu, Miao, Liu, Wei-Wei, Hao, Wen-Bo, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of asian natural products research (01.05.2012)
Published in Journal of asian natural products research (01.05.2012)
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Journal Article
Xanthoceraside attenuates amyloid beta peptide sub(25-35)-induced learning and memory impairments in mice
Lu, Ping, Mamiya, Takayoshi, Lu, Lingling, Mouri, Akihiro, Ikejima, Takashi, Kim, Hyoung-Chum, Zou, Li-Bo, Nabeshima, Toshitaka
Published in Psychopharmacology (01.01.2012)
Published in Psychopharmacology (01.01.2012)
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Journal Article
Xanthoceraside attenuates amyloid β [peptide.sub.25-35]-induced learning and memory impairments in mice
Lu, Ping, Mamiya, Takayoshi, Lu, Lingling, Mouri, Akihiro, Ikejima, Takashi, Kim, Hyoung-Chum, Zou, Li-Bo, Nabeshima, Toshitaka
Published in Psychopharmacology (01.01.2012)
Published in Psychopharmacology (01.01.2012)
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Journal Article
Xanthoceraside attenuates amyloid [beta] peptide^sub 25-35^-induced learning and memory impairments in mice
Lu, Ping, Mamiya, Takayoshi, Lu, Lingling, Mouri, Akihiro, Ikejima, Takashi, Kim, Hyoung-chum, Zou, Li-bo, Nabeshima, Toshitaka
Published in Psychopharmacology (01.01.2012)
Published in Psychopharmacology (01.01.2012)
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Nitric oxide augments oridonin-induced efferocytosis by human histocytic lymphoma U937 cells via autophagy and the NF- Delta kB-COX-2-IL-1 Delta b pathway
Zang, Linghe, He, Hao, Ye, Yuanchao, Liu, Weiwei, Fan, Simiao, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Free radical research (01.10.2012)
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Published in Free radical research (01.10.2012)
Journal Article
Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells
Yu, Jing-hua, Wang, Hong-jun, Li, Xiang-ru, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Acta pharmacologica Sinica (01.09.2008)
Published in Acta pharmacologica Sinica (01.09.2008)
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Induction of protective autophagy against apoptosis in HepG2 cells by isoniazid independent of the p38 signaling pathway
Zhang, Tian-Guang, Wang, Yi-Mei, Zhao, Jun, Xia, Ming-Yu, Peng, Shuang-Qing, Ikejima, Takashi
Published in Toxicology research (Cambridge) (01.05.2016)
Published in Toxicology research (Cambridge) (01.05.2016)
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Interruption of mitochondrial complex IV activity and cytochrome c expression activated O2∙−-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R–PI3K–Akt and IGF-1R–PLC γ–PKC pathways
Jiang, Yuan-yuan, Huang, Huai, Wang, Hong-jun, Wu, Di, Yang, Ri, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in European journal of pharmacology (01.10.2011)
Published in European journal of pharmacology (01.10.2011)
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Journal Article
Estrogen Receptors Are Involved in the Neuroprotective Effect of Silibinin in Aβ 1-42 -Treated Rats
Song, Xiaoyu, Liu, Bo, Cui, Lingyu, Zhou, Biao, Liu, Lu, Liu, Weiwei, Yao, Guodong, Xia, Mingyu, Hayashi, Toshihiko, Hattori, Shunji, Ushiki-Kaku, Yuko, Tashiro, Shin-Ichi, Ikejima, Takashi
Published in Neurochemical research (03.02.2018)
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Published in Neurochemical research (03.02.2018)
Journal Article
p38-NF-[kappa]B-promoted mitochondria-associated apoptosis and G2/M cell cycle arrest in norcantharidin-treated HeLa cells
Dong, Xiu, Li, Jian-Chun, Jiang, Yuan-Yuan, Xia, Ming-Yu, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of asian natural products research (01.11.2012)
Published in Journal of asian natural products research (01.11.2012)
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Journal Article
Reactive oxygen species H2O2 and OH, but not O2− promote oridonin-induced phagocytosis of apoptotic cells by human histocytic lymphoma U937 cells
Zang, Linghe, He, Hao, Xu, Qian, Yu, Yang, Zheng, Nan, Liu, Weiwei, Hayashi, Toshihiko, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in International immunopharmacology (01.02.2013)
Published in International immunopharmacology (01.02.2013)
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Journal Article
Induction of G 2 /M Phase Arrest and Apoptosis by Oridonin in Human Laryngeal Carcinoma Cells
Kang, Ning, Zhang, Jing-Hai, Qiu, Feng, Chen, Sheng, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of natural products (Washington, D.C.) (25.06.2010)
Published in Journal of natural products (Washington, D.C.) (25.06.2010)
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Journal Article
Silibinin ameliorates Aβ 25-35 -induced memory deficits in rats by modulating autophagy and attenuating neuroinflammation as well as oxidative stress
Song, Xiaoyu, Zhou, Biao, Cui, Lingyu, Lei, Di, Zhang, Pingping, Yao, Guodong, Xia, Mingyu, Hayashi, Toshihiko, Hattori, Shunji, Ushiki-Kaku, Yuko, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Neurochemical research (01.04.2017)
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Published in Neurochemical research (01.04.2017)
Journal Article
Oridonin induces G sub(2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells)
Cheng, Yan, Qiu, Feng, Ye, Yuan-Chao, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Archives of biochemistry and biophysics (01.10.2009)
Published in Archives of biochemistry and biophysics (01.10.2009)
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Journal Article
Silibinin induces the generation of nitric oxide in human breast cancer MCF-7 cells
Wang, Hong-Jun, Wei, Xiao-Feng, Jiang, Yuan-Yuan, Huang, Huai, Yang, Ying, Fan, Si-Miao, Zang, Ling-He, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Free radical research (2010)
Published in Free radical research (2010)
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Journal Article
p53-mediated autophagy adjustment is involved in the protection of silibinin against murine dermal inflammation and epidermal apoptosis induced by UVB irradiation
Wang, Qiong, Liu, Weiwei, Zeng, Hong, Xie, Xuqin, Zang, Guangxi, Ye, Yuanchao, Tashiro, Shin-ichi, Onodera, Satoshi, Jiang, Shan, Ikejima, Takashi
Published in Journal of asian natural products research (01.02.2013)
Published in Journal of asian natural products research (01.02.2013)
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Journal Article
Silibinin activated ROS-p38-NF-κB positive feedback and induced autophagic death in human fibrosarcoma HT1080 cells
Duan, Wen-Jun, Li, Qi-Sheng, Xia, Ming-Yu, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of asian natural products research (01.01.2011)
Published in Journal of asian natural products research (01.01.2011)
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