Donepezil Hydrochloride (E2020) and Other Acetylcholinesterase Inhibitors
Sugimoto, H, Yamanishi, Y, Iimura, Y, Kawakami, Y
Published in Current medicinal chemistry (01.03.2000)
Published in Current medicinal chemistry (01.03.2000)
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Synthesis and Structure-Activity Relationships of Acetylcholinesterase Inhibitors: 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine Hydrochloride and Related Compounds
Sugimoto, Hachiro, Iimura, Youichi, Yamanishi, Yoshiharu, Yamatsu, Kiyomi
Published in Journal of medicinal chemistry (01.11.1995)
Published in Journal of medicinal chemistry (01.11.1995)
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Effect of cupula shrinkage on the semicircular canal activity
Iimura, Youichi, Suzuki, Mamoru, Otsuka, Koji, Inagaki, Taro, Konomi, Ujimoto, Shimizu, Shigetaka
Published in Acta oto-laryngologica (01.10.2010)
Published in Acta oto-laryngologica (01.10.2010)
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A novel transformation of four aldoses to some optically pure pseudohexopyranoses and a pseudopentofuranose, carbocyclic analogs of hexopyranoses and pentofuranose. Synthesis of derivatives of (1S,2S,3R,4S,5S)-, (1S,2S,3R,4R,5S)-, (1R,2R,3R,4R,5S)-, (1S,2S,3R,4S,5R)-2,3,4,5-tetrahydroxy-1-(hydroxymethyl)cyclohexanes and (1S,2S,3S,4S)-2,3,4-trihydroxy-1(hydroxymethyl)cyclopentane
Tadano, Kinichi, Maeda, Hiroo, Hoshino, Masahide, Iimura, Youichi, Suami, Tetsuo
Published in Journal of organic chemistry (01.05.1987)
Published in Journal of organic chemistry (01.05.1987)
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The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1H-inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses
Inoue, Atsushi, Kawai, Takatoshi, Wakita, Misako, Iimura, Youichi, Sugimoto, Hachiro, Kawakami, Yoshiyuki
Published in Journal of medicinal chemistry (25.10.1996)
Published in Journal of medicinal chemistry (25.10.1996)
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Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds
Sugimoto, Hachiro, Iimura, Youichi, Yamanishi, Yoshiharu, Yamatsu, Kiyomi
Published in Bioorganic & medicinal chemistry letters (1992)
Published in Bioorganic & medicinal chemistry letters (1992)
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OXAZOLIDONE DERIVATIVE
AKASAKA, KOZO, NAGATO, SATOSHI, KAJIWARA, AKIHARA, SASAKI, ATSUSHI, YOSHIDA, ICHIROU, IIMURA, YOUICHI, KAGAYA, TAKAKI, KOMATSU, MARIK, KUBOTA, ATSUHIKO, MIZUNO, MASANORI
Year of Publication 09.07.1997
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Year of Publication 09.07.1997
Patent
OXAZOLIDONE DERIVATIVE
KAJIWARA, AKIHARU, AKASAKA, KOZO, NAGATO, SATOSHI, SASAKI, ATSUSHI, YOSHIDA, ICHIROU, IIMURA, YOUICHI, KAGAYA, TAKAKI, KUBOTA, ATSUHIKO, MIZUNO, MASANORI
Year of Publication 29.04.1993
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Year of Publication 29.04.1993
Patent
Conformational analyses and molecular-shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase
Cardozo, Mario G, Kawai, Takatoshi, Iimura, Youichi, Sugimoto, Hachiro, Yamanishi, Yoshiharu, Hopfinger, A. J
Published in Journal of medicinal chemistry (01.02.1992)
Published in Journal of medicinal chemistry (01.02.1992)
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Journal Article
The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1 H -inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses
Inoue, Atsushi, Kawai, Takatoshi, Wakita, Misako, Iimura, Youichi, Sugimoto, Hachiro, Kawakami, Yoshiyuki
Published in Journal of medicinal chemistry (01.01.1996)
Published in Journal of medicinal chemistry (01.01.1996)
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Journal Article
Discovery and Development of Donepezil Hydrochloride for the Treatment of Alzheimer's Disease
SUGIMOTO, Hachiro, YAMANISHI, Yoshiharu, OGURA, Hiroo, IIMURA, Youichi, YAMATSU, Kiyomi
Published in YAKUGAKU ZASSHI (01.02.1999)
Published in YAKUGAKU ZASSHI (01.02.1999)
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CYCLIC AMINE COMPOUNDS
IIMURA YOUICHI, YANATSU KIYOMI, HIGUSRASHI KUNIZO, KOSAGA TAKASHI, KARIBE NORIO, KUBOTA ATSUHIKO, KOSASA MICHIKO, YAMANISHI YOSHIHARU, SUGIMOTO MACHIRO, OGURA HIROO, SASAKI JUN, ARAKI SHIN, TSUCHIYA YUTAKA
Year of Publication 07.06.1991
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Year of Publication 07.06.1991
Patent
Quantitative structure-activity relationship. QSAR, analyses of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. [Erratum to document cited in CA116(9):83138p]
Cardozo, Mario G, Iimura, Youichi, Sugimoto, Hachiro, Yamanishi, Yoshiharu, Hopfinger, A. J
Published in Journal of medicinal chemistry (01.12.1992)
Published in Journal of medicinal chemistry (01.12.1992)
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Journal Article
Quantitative structure-activity relationship. QSAR, analyses of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase
Cardozo, Mario G, Iimura, Youichi, Sugimoto, Hachiro, Yamanishi, Yoshiharu, Hopfinger, A. J
Published in Journal of medicinal chemistry (01.02.1992)
Published in Journal of medicinal chemistry (01.02.1992)
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Journal Article
Conformational analyses and molecular-shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. [Erratum to document cited in CA116(11):98893e]
Cardozo, Mario G, Kawai, Takatoshi, Iimura, Youichi, Sugimoto, Hachiro, Yamanishi, Yoshiharu, Hopfinger, A. J
Published in Journal of medicinal chemistry (01.12.1992)
Published in Journal of medicinal chemistry (01.12.1992)
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Journal Article