Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?
McHenry, Michael L, Bartlett, Jacquelaine, Igo, Jr, Robert P, Wampande, Eddie M, Benchek, Penelope, Mayanja-Kizza, Harriet, Fluegge, Kyle, Hall, Noemi B, Gagneux, Sebastien, Tishkoff, Sarah A, Wejse, Christian, Sirugo, Giorgio, Boom, W Henry, Joloba, Moses, Williams, Scott M, Stein, Catherine M
Published in PLoS genetics (01.04.2020)
Published in PLoS genetics (01.04.2020)
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AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection
Papp, Audrey C, Azad, Abul K, Pietrzak, Maciej, Williams, Amanda, Handelman, Samuel K, Igo, Jr, Robert P, Stein, Catherine M, Hartmann, Katherine, Schlesinger, Larry S, Sadee, Wolfgang
Published in PloS one (30.05.2018)
Published in PloS one (30.05.2018)
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Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
Khawaja, Anthony P, Cooke Bailey, Jessica N, Wareham, Nicholas J, Scott, Robert A, Simcoe, Mark, Igo, Jr, Robert P, Song, Yeunjoo E, Wojciechowski, Robert, Cheng, Ching-Yu, Khaw, Peng T, Pasquale, Louis R, Haines, Jonathan L, Foster, Paul J, Wiggs, Janey L, Hammond, Chris J, Hysi, Pirro G
Published in Nature genetics (01.06.2018)
Published in Nature genetics (01.06.2018)
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Genetic evidence for role of carotenoids in age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS)
Meyers, Kristin J, Mares, Julie A, Igo, Jr, Robert P, Truitt, Barbara, Liu, Zhe, Millen, Amy E, Klein, Michael, Johnson, Elizabeth J, Engelman, Corinne D, Karki, Chitra K, Blodi, Barbara, Gehrs, Karen, Tinker, Lesley, Wallace, Robert, Robinson, Jennifer, LeBlanc, Erin S, Sarto, Gloria, Bernstein, Paul S, SanGiovanni, John Paul, Iyengar, Sudha K
Published in Investigative ophthalmology & visual science (29.01.2014)
Published in Investigative ophthalmology & visual science (29.01.2014)
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Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy
Afshari, Natalie A, Igo, Jr, Robert P, Morris, Nathan J, Stambolian, Dwight, Sharma, Shiwani, Pulagam, V Lakshmi, Dunn, Steven, Stamler, John F, Truitt, Barbara J, Rimmler, Jacqueline, Kuot, Abraham, Croasdale, Christopher R, Qin, Xuejun, Burdon, Kathryn P, Riazuddin, S Amer, Mills, Richard, Klebe, Sonja, Minear, Mollie A, Zhao, Jiagang, Balajonda, Elmer, Rosenwasser, George O, Baratz, Keith H, Mootha, V Vinod, Patel, Sanjay V, Gregory, Simon G, Bailey-Wilson, Joan E, Price, Marianne O, Price, Jr, Francis W, Craig, Jamie E, Fingert, John H, Gottsch, John D, Aldave, Anthony J, Klintworth, Gordon K, Lass, Jonathan H, Li, Yi-Ju, Iyengar, Sudha K
Published in Nature communications (30.03.2017)
Published in Nature communications (30.03.2017)
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Genetic Risk Scores
Igo, Jr, Robert P, Kinzy, Tyler G, Cooke Bailey, Jessica N
Published in Current protocols in human genetics (01.12.2019)
Published in Current protocols in human genetics (01.12.2019)
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Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study
Meyers, Kristin J, Johnson, Elizabeth J, Bernstein, Paul S, Iyengar, Sudha K, Engelman, Corinne D, Karki, Chitra K, Liu, Zhe, Igo, Jr, Robert P, Truitt, Barbara, Klein, Michael L, Snodderly, D Max, Blodi, Barbara A, Gehrs, Karen M, Sarto, Gloria E, Wallace, Robert B, Robinson, Jennifer, LeBlanc, Erin S, Hageman, Gregory, Tinker, Lesley, Mares, Julie A
Published in Investigative ophthalmology & visual science (28.03.2013)
Published in Investigative ophthalmology & visual science (28.03.2013)
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Journal Article
Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4
Margeta, Milica A, Letcher, Sophia M, Igo, Jr, Robert P, Cooke Bailey, Jessica N, Pasquale, Louis R, Haines, Jonathan L, Butovsky, Oleg, Wiggs, Janey L
Published in Investigative ophthalmology & visual science (01.07.2020)
Published in Investigative ophthalmology & visual science (01.07.2020)
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Journal Article
Differential Long-Term Outcomes for Individuals With Histories of Preschool Speech Sound Disorders
Lewis, Barbara A, Freebairn, Lisa, Tag, Jessica, Igo, Jr, Robert P, Ciesla, Allison, Iyengar, Sudha K, Stein, Catherine M, Taylor, H Gerry
Published in American journal of speech-language pathology (01.11.2019)
Published in American journal of speech-language pathology (01.11.2019)
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Journal Article
A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa
Sobota, Rafal S, Stein, Catherine M, Kodaman, Nuri, Maro, Isaac, Wieland-Alter, Wendy, Igo, Jr, Robert P, Magohe, Albert, Malone, LaShaunda L, Chervenak, Keith, Hall, Noemi B, Matee, Mecky, Mayanja-Kizza, Harriet, Joloba, Moses, Moore, Jason H, Scott, William K, Lahey, Timothy, Boom, W Henry, von Reyn, C Fordham, Williams, Scott M, Sirugo, Giorgio
Published in PLoS genetics (19.06.2017)
Published in PLoS genetics (19.06.2017)
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Vitamin D Intake and Season Modify the Effects of the GC and CYP2R1 Genes on 25-Hydroxyvitamin D Concentrations
Engelman, Corinne D., Meyers, Kristin J., Iyengar, Sudha K., Liu, Zhe, Karki, Chitra K., Igo, Robert P., Truitt, Barbara, Robinson, Jennifer, Sarto, Gloria E., Wallace, Robert, Blodi, Barbara A., Klein, Michael L., Tinker, Lesley, LeBlanc, Erin S., Jackson, Rebecca D., Song, Yiqing, Manson, JoAnn E., Mares, Julie A., Millen, Amy E.
Published in The Journal of nutrition (01.01.2013)
Published in The Journal of nutrition (01.01.2013)
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Differing roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy
Igo, Jr, Robert P, Kopplin, Laura J, Joseph, Peronne, Truitt, Barbara, Fondran, Jeremy, Bardenstein, David, Aldave, Anthony J, Croasdale, Christopher R, Price, Marianne O, Rosenwasser, Miriam, Lass, Jonathan H, Iyengar, Sudha K
Published in PloS one (23.10.2012)
Published in PloS one (23.10.2012)
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Journal Article
Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes
Laville, Vincent, Kang, Jae H., Cousins, Clara C., Iglesias, Adriana I., Nagy, Réka, Cooke Bailey, Jessica N., Igo, Robert P., Song, Yeunjoo E., Chasman, Daniel I., Christen, William G., Kraft, Peter, Rosner, Bernard A., Hu, Frank, Wilson, James F., Gharahkhani, Puya, Hewitt, Alex W., Mackey, David A., Hysi, Pirro G., Hammond, Christopher J., vanDuijn, Cornelia M., Haines, Jonathan L., Vitart, Veronique, Fingert, John H., Hauser, Michael A., Aschard, Hugues, Wiggs, Janey L., Khawaja, Anthony P., MacGregor, Stuart, Pasquale, Louis R.
Published in American journal of ophthalmology (01.10.2019)
Published in American journal of ophthalmology (01.10.2019)
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Journal Article
Genomic Disorders in CKD across the Lifespan
Verbitsky, Miguel, Krishnamurthy, Sarathbabu, Krithivasan, Priya, Hughes, Daniel, Khan, Atlas, Marasà, Maddalena, Vena, Natalie, Khosla, Pavan, Zhang, Junying, Lim, Tze Y, Glessner, Joseph T, Weng, Chunhua, Shang, Ning, Shen, Yufeng, Hripcsak, George, Hakonarson, Hakon, Ionita-Laza, Iuliana, Levy, Brynn, Kenny, Eimear E, Loos, Ruth J F, Kiryluk, Krzysztof, Sanna-Cherchi, Simone, Crosslin, David R, Furth, Susan, Warady, Bradley A, Igo, Jr, Robert P, Iyengar, Sudha K, Wong, Craig S, Parsa, Afshin, Feldman, Harold I, Gharavi, Ali G
Published in Journal of the American Society of Nephrology (01.04.2023)
Published in Journal of the American Society of Nephrology (01.04.2023)
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Journal Article
Association of smoking and other risk factors with Fuchs' endothelial corneal dystrophy severity and corneal thickness
Zhang, Xiaolin, Igo, Jr, Robert P, Fondran, Jeremy, Mootha, V Vinod, Oliva, Matt, Hammersmith, Kristin, Sugar, Alan, Lass, Jonathan H, Iyengar, Sudha K
Published in Investigative ophthalmology & visual science (27.08.2013)
Published in Investigative ophthalmology & visual science (27.08.2013)
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Journal Article
Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration
Waksmunski, Andrea R, Grunin, Michelle, Kinzy, Tyler G, Igo, Jr, Robert P, Haines, Jonathan L, Cooke Bailey, Jessica N
Published in BMC medical genomics (06.07.2020)
Published in BMC medical genomics (06.07.2020)
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Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma
Gharahkhani, Puya, Burdon, Kathryn P, Cooke Bailey, Jessica N, Hewitt, Alex W, Law, Matthew H, Pasquale, Louis R, Kang, Jae H, Haines, Jonathan L, Souzeau, Emmanuelle, Zhou, Tiger, Siggs, Owen M, Landers, John, Awadalla, Mona, Sharma, Shiwani, Mills, Richard A, Ridge, Bronwyn, Lynn, David, Casson, Robert, Graham, Stuart L, Goldberg, Ivan, White, Andrew, Healey, Paul R, Grigg, John, Lawlor, Mitchell, Mitchell, Paul, Ruddle, Jonathan, Coote, Michael, Walland, Mark, Best, Stephen, Vincent, Andrea, Gale, Jesse, RadfordSmith, Graham, Whiteman, David C, Montgomery, Grant W, Martin, Nicholas G, Mackey, David A, Wiggs, Janey L, MacGregor, Stuart, Craig, Jamie E
Published in Scientific reports (15.02.2018)
Published in Scientific reports (15.02.2018)
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HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma
Zein, Joe, Gaston, Benjamin, Bazeley, Peter, DeBoer, Mark D., Igo, Robert P., Bleecker, Eugene R., Meyers, Deborah, Comhair, Suzy, Marozkina, Nadzeya V., Cotton, Calvin, Patel, Mona, Alyamani, Mohammad, Xu, Weiling, Busse, William W., Calhoun, William J., Ortega, Victor, Hawkins, Gregory A., Castro, Mario, Chung, Kian Fan, Fahy, John V., Fitzpatrick, Anne M., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce, Mauger, David T., Moore, Wendy C., Noel, Patricia, Peters, Stephen P., Teague, W. Gerald, Wenzel, Sally E., Erzurum, Serpil C., Sharifi, Nima
Published in Proceedings of the National Academy of Sciences - PNAS (28.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (28.01.2020)
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AMISH EYE STUDY: Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration
Nittala, Muneeswar G, Song, Yeunjoo E, Sardell, Rebecca, Adams, Larry D, Pan, Samuel, Velaga, Swetha B, Horst, Violet, Dana, Debra, Caywood, Laura, Laux, Renee, Fuzzell, Denise, Fuzzell, Sarada, Scott, William K, Cooke Bailey, Jessica N, Igo, Jr, Robert P, Haines, Jonathan, Pericak-Vance, Margaret A, Sadda, SriniVas R, Stambolian, Dwight
Published in Retina (Philadelphia, Pa.) (01.08.2019)
Published in Retina (Philadelphia, Pa.) (01.08.2019)
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A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals
Sobota, Rafal S., Stein, Catherine M., Kodaman, Nuri, Scheinfeldt, Laura B., Maro, Isaac, Wieland-Alter, Wendy, Igo, Robert P., Magohe, Albert, Malone, LaShaunda L., Chervenak, Keith, Hall, Noemi B., Modongo, Chawangwa, Zetola, Nicola, Matee, Mecky, Joloba, Moses, Froment, Alain, Nyambo, Thomas B., Moore, Jason H., Scott, William K., Lahey, Timothy, Boom, W. Henry, von Reyn, C. Fordham, Tishkoff, Sarah A., Sirugo, Giorgio, Williams, Scott M.
Published in American journal of human genetics (03.03.2016)
Published in American journal of human genetics (03.03.2016)
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