First Indications Demonstrating the Preventive Effects of NZ-419, a Novel Intrinsic Antioxidant, on the Initiation and/or Progression of Chronic Renal Failure in Rats
Ienaga, Kazuharu, Mikami, Hiroki, Yokozawa, Takako
Published in Biological & Pharmaceutical Bulletin (01.07.2009)
Published in Biological & Pharmaceutical Bulletin (01.07.2009)
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Daily hydroxyl radical scavenging capacity of mammals
Ienaga, Kazuharu, Park, Chan Hum, Yokozawa, Takako
Published in Drug Discoveries & Therapeutics (01.04.2014)
Published in Drug Discoveries & Therapeutics (01.04.2014)
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Advanced Glycation End Products Induce Expression of Vascular Endothelial Growth Factor by Retinal Müller Cells
Hirata, Chizuko, Nakano, Koji, Nakamura, Naoto, Kitagawa, Yoshihiro, Shigeta, Hirofumi, Hasegawa, Goji, Ogata, Masakazu, Ikeda, Tsunehiko, Sawa, Hiroshi, Nakamura, Ko, Ienaga, Kazuharu, Obayashi, Hiroshi, Kondo, Motoharu
Published in Biochemical and biophysical research communications (30.07.1997)
Published in Biochemical and biophysical research communications (30.07.1997)
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Journal Article
Highly Selective Aldose Reductase Inhibitors. 1. 3-(Arylalkyl)-2,4,5-trioxoimidazolidine-1-acetic Acids
Ishii, Akira, Kotani, Takayuki, Nagaki, Yasuhiro, Shibayama, Yoji, Toyomaki, Yoshio, Okukado, Nobuhisa, Ienaga, Kazuharu, Okamoto, Kaoru
Published in Journal of medicinal chemistry (26.04.1996)
Published in Journal of medicinal chemistry (26.04.1996)
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Journal Article
Protective effect of an intrinsic antioxidant, HMH (5-hydroxy-1-methylhydantoin; NZ-419), against cellular damage of kidney tubules
Ienaga, Kazuharu, Park, Chan Hum, Yokozawa, Takako
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.07.2013)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.07.2013)
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A Simple Conversion of Creatinine to Creatol via Creatinine Chloroamine
Ienaga, Kazuharu, Toya, Yoshiaki, Nakajima, Kiyohiko, Tachikawa, Mariko
Published in Australian journal of chemistry (01.01.2015)
Published in Australian journal of chemistry (01.01.2015)
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The role of protein kinase C in the increased generation in isolated rat hepatocytes of the hydroxyl radical by puromycin aminonucleoside
Aoyagi, Kazumasa, Shahrzad, Siranoush, Kuzure, Yutaka, Koyama, Akio, Nakamura, Ko, Ienaga, Kazuharu
Published in Free radical research (01.01.2000)
Published in Free radical research (01.01.2000)
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Synthesis of creatol, a hydroxyl radical adduct of creatinine and its increase by puromycin aminonucleoside in isolated rat hepatocytes
Aoyagi, Kazumasa, Akiyama, Kayo, Kuzure, Yutaka, Takemura, Katsumi, Nagase, Sohji, Ienaga, Kazuharu, Nakamura, Ko, Koyama, Akio, Narita, Mitsuharu
Published in Free radical research (01.01.1998)
Published in Free radical research (01.01.1998)
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Effect of Neurotropin ® on the Binding of High Molecular Weight Kininogen and Hageman Factor to Human Umbilical Vein Endothelial Cells and the Autoactivation of Bound Hageman Factor
Shibayama, Yoji, Reddigari, Sesha R, Teruya, Minako, Nakamura, Ko, Fukunaga, Yasutsugu, Ienaga, Kazuharu, Nishikawa, Katsumi, Suehiro, Seishi, Kaplan, Allen P
Published in Biochemical pharmacology (15.04.1998)
Published in Biochemical pharmacology (15.04.1998)
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Journal Article
In vivo Effect of Hydroxyl Radical Scavenger on Methylguanidine Production from Creatinine
Yokozawa, Takako, Fujitsuka, Naoki, Oura, Hikokichi, Ienaga, Kazuharu, Nakamura, Ko
Published in Nephron (01.01.1997)
Published in Nephron (01.01.1997)
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Journal Article
Changes in Serum Levels of Creatol and Methylguanidine in Renal Injury Induced by Lipid Peroxide Produced by Vitamin E Deficiency and GSH Depletion in Rats
Ozasa, Hisashi, Watanabe, Tomoe, Nakamura, Ko, Fukunaga, Yasutsugu, Ienaga, Kazuharu, Hagiwara, Kiyokazu
Published in Nephron (1997)
Published in Nephron (1997)
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Journal Article
Creatinine metabolite, HMH (5-hydroxy-1-methylhydantoin; NZ-419), modulates bradykinin-induced changes in vascular smooth muscle cells
Ienaga, Kazuharu, Sohn, Mimi, Naiki, Mitsuru, Jaffa, Ayad A
Published in Journal of receptors and signal transduction (01.06.2014)
Published in Journal of receptors and signal transduction (01.06.2014)
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