YM-359445, an Orally Bioavailable Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitor, Has Highly Potent Antitumor Activity against Established Tumors
Amino, Nobuaki, Ideyama, Yukitaka, Yamano, Mayumi, Kuromitsu, Sadao, Tajinda, Katsuinori, Samizu, Kiyohiro, Hisamichi, Hiroyuki, Matsuhisa, Akira, Shirasuna, Kenna, Kudoh, Masafumi, Shibasaki, Masayuki
Published in Clinical cancer research (01.03.2006)
Published in Clinical cancer research (01.03.2006)
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Journal Article
YM-231146, a Novel Orally Bioavailable Inhibitor of Vascular Endothelial Growth Factor Receptor-2, Is Effective against Paclitaxel Resistant Tumors
Amino, Nobuaki, Ideyama, Yukitaka, Yamano, Mayumi, Kuromitsu, Sadao, Tajinda, Katsunori, Samizu, Kiyohiro, Matsuhisa, Akira, Shirasuna, Kenna, Kudoh, Masafumi, Shibasaki, Masayuki
Published in Biological & Pharmaceutical Bulletin (01.11.2005)
Published in Biological & Pharmaceutical Bulletin (01.11.2005)
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Journal Article
A five-alpha reductase inhibitor or an antiandrogen prevents the progression of microscopic prostate carcinoma to macroscopic carcinoma in rats
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Conference Proceeding
Journal Article
Inhibitory effect of a novel non-steroidal aromatase inhibitor, YM511 on the proliferation of MCF-7 human breast cancer cell
Kudoh, Masafumi, Susaki, Yoko, Ideyama, Yukitaka, Nanya, Taiki, Mori, Masamichi, Shikama, Hisataka, Fujikura, Takashi
Published in The Journal of steroid biochemistry and molecular biology (01.05.1996)
Published in The Journal of steroid biochemistry and molecular biology (01.05.1996)
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Journal Article
YM-201627: An orally active antitumor agent with selective inhibition of vascular endothelial cell proliferation
Amino, Nobuaki, Ideyama, Yukitaka, Yamano, Mayumi, Kuromitsu, Sadao, Tajinda, Katsunori, Samizu, Kiyohiro, Matsuhisa, Akira, Kudoh, Masafumi, Shibasaki, Masayuki
Published in Cancer letters (08.07.2006)
Published in Cancer letters (08.07.2006)
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Journal Article
Persistence of prostatic intraepithelial neoplasia after effective chemoprevention of microscopic prostate cancer with antiandrogen in a rat model
Yamauchi, Atsushi, Kawai, Koji, Tsukamoto, Sadamu, Ideyama, Yukitaka, Shirai, Tomoyuki, Akaza, Hideyuki
Published in The Journal of urology (01.01.2006)
Published in The Journal of urology (01.01.2006)
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Journal Article
ANTAGONIST FOR MUTATED ANDROGEN RECEPTOR
FURUTANI TAKASHI, TANIGUCHI NOBUAKI, SUGANE TAKASHI, YAMADA TOMOHIRO, WATANABE KAZUSHI, HIRANO MASAAKI, KONAGAI SATOSHI, TAKEDA MASAYOSHI, KONDOH YUTAKA, KAKEFUDA AKIO, IDEYAMA YUKITAKA, KUROMITSU SADAO
Year of Publication 23.12.2013
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Year of Publication 23.12.2013
Patent
YM116, 2-(1H-Imidazol-4-ylmethyl)-9H-carbazole, Decreases Adrenal Androgen Synthesis by Inhibiting C17-20 Lyase Activity in NCI-H295 Human Adrenocortical Carcinoma Cells
Ideyama, Yukitaka, Kudoh, Masafumi, Tanimoto, Kyoko, Susaki, Yoko, Nanya, Taiki, Nakahara, Takahito, Ishikawa, Hiroko, Fujikura, Takashi, Akaza, Hideyuki, Shikama, Hisataka
Published in Japanese Journal of Pharmacology (1999)
Published in Japanese Journal of Pharmacology (1999)
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Journal Article
METHOD FOR SCREENING SUBSTANCE USEFUL AS THERAPEUTIC AGENT FOR PROSTATE CANCER
IDEYAMA, YUKITAKA, ENJO, KENTARO, KIKUCHI, AYA, SUZUKI, TOMOYUKI, FURUTANI, TAKASHI, KURIHARA, RYOKO, KUROMITSU, SADAO
Year of Publication 05.08.2010
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Year of Publication 05.08.2010
Patent
YM-359445, an orally bioavailable vascular endothelial growth factor receptor-2 tyrosine klinase inhibitor, has highly potent antitumor activity against established tumors
AMINO, Nobuaki, IDEYAMA, Yukitaka, SHIBASAKI, Masayuki, YAMANO, Mayumi, KUROMITSU, Sadao, TAJINDA, Katsuinori, SAMIZU, Kiyohiro, HISAMICHI, Hiroyuki, MATSUHISA, Akira, SHIRASUNA, Kenna, KUDOH, Masafumi
Published in Clinical cancer research (2006)
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Published in Clinical cancer research (2006)
Journal Article
ANTAGONIST FOR MUTATED ANDROGEN RECEPTOR
KAKEFUDA, AKIO, WATANABE, KAZUSHI, HIRANO, MASAAKI, KONDOH, YUTAKA, KONAGAI, SATOSHI, TANIGUCHI, NOBUAKI, IDEYAMA, YUKITAKA, FURUTANI, TAKASHI, KUROMITSU, SADAO, TAKEDA, MASAYOSHI, YAMADA, TOMOHIRO, SUGANE, TAKASHI
Year of Publication 26.04.2012
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Year of Publication 26.04.2012
Patent
Promoting effects and mechanisms of action of androgen in bladder carcinogenesis in male rats
Imada, S, Akaza, H, Ami, Y, Koiso, K, Ideyama, Y, Takenaka, T
Published in European urology (01.01.1997)
Published in European urology (01.01.1997)
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Journal Article
2-OXOINDOLINE DERIVATIVES
SAMIZU, KIYOHIRO, HISAMICHI, HIROYUKI, MATSUHISA, AKIRA, IDEYAMA, YUKITAKA, KUROMITSU, SADAO
Year of Publication 10.06.2004
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Year of Publication 10.06.2004
Patent
YM116, 2-(1H-Imidazol-4-ylmethyl)-9H-carbazole, Decreases Adrenal Androgen Synthesis by Inhibiting Cl7-20 Lyase Activity in NCI-H295 Human Adrenocortical Carcinoma Cells
Yukitaka, Ideyama, Masafumi, Kudoh, Kyoko, Tanimoto, Yoko, Susaki, Taiki, Nanya, Takahito, Nakahara, Hiroko, Ishikawa, Takashi, Fujikura, Hideyuki, Akaza, Hisataka, Shikama
Published in Japanese journal of pharmacology (1999)
Published in Japanese journal of pharmacology (1999)
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Journal Article
Inhibitory effects of a novel aromatase inhibitor, YM511, on growth of endometrial explants and insulin-like growth factor-I gene expression in rats with experimental endometriosis
Kudoh, Masafumi, Susaki, Yoko, Ideyama, Yukitaka, Nanya, Taiki, Mori, Masamichi, Shikama, Hisataka
Published in The Journal of steroid biochemistry and molecular biology (01.09.1997)
Published in The Journal of steroid biochemistry and molecular biology (01.09.1997)
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Journal Article
3−QUINOLINE−2−(1H)−YLIDENEINDOLIN−2−ONE DERIVATIVES
SAMIZU, KIYOHIRO, HAYAKAWA, MASAHIKO, HISAMICHI, HIROYUKI, MATSUHISA, AKIRA, TANIGUCHI, NOBUAKI, IDEYAMA, YUKITAKA, OKADA, MINORU, YAHIRO, KIYOSHI, KINOYAMA, ISAO, KUROMITSU, SADAO
Year of Publication 28.11.2002
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Year of Publication 28.11.2002
Patent
FUSED IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF
SAKUDA, SHUICHI, ISHIHARA, TSUKASA, IDEYAMA, YUKITAKA, KUDOH, MASAFUMI, OKADA, MINORU, KINOYAMA, ISAO, YODEN, TORU
Year of Publication 03.01.1997
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Year of Publication 03.01.1997
Patent
IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF
ISHIHARA, TSUKASA, IDEYAMA, YUKITAKA, KUDOH, MASAFUMI, OKADA, MINORU, SAKUDA, SYUICHI, KINOYAMA, ISAO, YODEN, TORU
Year of Publication 06.09.1996
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Year of Publication 06.09.1996
Patent