Infantile mitochondrial hepatopathy is a cardinal feature of MEGDEL syndrome (3-Methylglutaconic aciduria type IV with sensorineural deafness, encephalopathy and leigh-Like Syndrome) caused by novel mutations in SERAC1
Sarig, Ofer, Goldsher, Dorit, Nousbeck, Janna, Fuchs-Telem, Dana, Cohen-Katsenelson, Ksenya, Iancu, Theodore C., Manov, Irena, Saada, Ann, Sprecher, Eli, Mandel, Hanna
Published in American journal of medical genetics. Part A (01.09.2013)
Published in American journal of medical genetics. Part A (01.09.2013)
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Journal Article
Iron-rich ferritin in the hypoxia-tolerant rodent Spalax ehrenbergi: A naturally-occurring biomarker confirms the internalization and pathways of intracellular macromolecules
Iancu, Theodore C., Arad, Talmon, Shams, Imad, Manov, Irena
Published in Journal of structural biology (01.09.2014)
Published in Journal of structural biology (01.09.2014)
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Journal Article
ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation
Jansen, Eric J. R., Timal, Sharita, Ryan, Margret, Ashikov, Angel, van Scherpenzeel, Monique, Graham, Laurie A., Mandel, Hanna, Hoischen, Alexander, Iancu, Theodore C., Raymond, Kimiyo, Steenbergen, Gerry, Gilissen, Christian, Huijben, Karin, van Bakel, Nick H. M., Maeda, Yusuke, Rodenburg, Richard J., Adamowicz, Maciej, Crushell, Ellen, Koenen, Hans, Adams, Darius, Vodopiutz, Julia, Greber-Platzer, Susanne, Müller, Thomas, Dueckers, Gregor, Morava, Eva, Sykut-Cegielska, Jolanta, Martens, Gerard J. M., Wevers, Ron A., Niehues, Tim, Huynen, Martijn A., Veltman, Joris A., Stevens, Tom H., Lefeber, Dirk J.
Published in Nature communications (27.05.2016)
Published in Nature communications (27.05.2016)
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High-Dose Acetaminophen Inhibits the Lethal Effect of Doxorubicin in HepG2 Cells: The Role of P-glycoprotein and Mitogen-Activated Protein Kinase p44/42 Pathway
Irena Manov, Yulia Bashenko, Anat Eliaz-Wolkowicz, Meital Mizrahi, Oded Liran, Theodore C. Iancu
Published in The Journal of pharmacology and experimental therapeutics (01.09.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2007)
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Journal Article
Inhibition of doxorubicin‐induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib – the role of extracellular signal‐regulated kinase counteraction
Manov, Irena, Pollak, Yulia, Broneshter, Rinata, Iancu, Theodore C.
Published in The FEBS journal (01.09.2011)
Published in The FEBS journal (01.09.2011)
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Journal Article
Acetaminophen hepatotoxicity and mechanisms of its protection by N-acetylcysteine: a study of Hep3B cells
Manov, Irena, Hirsh, Mark, Iancu, Theodore C.
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (2002)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (2002)
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What's in a Name?-"Lipolysosome": Ultrastructural Features of a Lipid-containing Organelle
Iancu, Theodore C., Manov, Irena, Shaoul, Ron, Haimi, Motti, Lerner, Aaron
Published in Ultrastructural pathology (01.10.2013)
Published in Ultrastructural pathology (01.10.2013)
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Journal Article
Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus
Asleh, Rabea, Nakhoul, Farid M., Miller-Lotan, Rachel, Awad, Hoda, Farbstein, Dan, Levy, Nina S., Nakhoul, Nakhoul, Iancu, Theodore C., Manov, Irena, Laue, Michael, Traber, Maret G., Lebold, Katie M., Levy, Andrew P.
Published in Free radical biology & medicine (15.08.2012)
Published in Free radical biology & medicine (15.08.2012)
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Effects of novel neuroprotective and neurorestorative multifunctional drugs on iron chelation and glucose metabolism
Pollak, Yulia, Mechlovich, Danit, Amit, Tamar, Bar-Am, Orit, Manov, Irena, Mandel, Silvia A., Weinreb, Orly, Meyron-Holtz, Esther G., Iancu, Theodore C., Youdim, Moussa B. H.
Published in Journal of Neural Transmission (2013)
Published in Journal of Neural Transmission (2013)
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Journal Article
Severe lysosomal storage disease of liver in del(1)(p36): A new presentation
Haimi, Motti, Iancu, Theodore C, Shaffer, Lisa G, Lerner, Aaron
Published in European journal of medical genetics (01.05.2011)
Published in European journal of medical genetics (01.05.2011)
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Journal Article
Microvillous Inclusion Disease: Ultrastructural Variability
Iancu, Theodore C., Mahajnah, Muhammad, Manov, Irena, Shaoul, Ron
Published in Ultrastructural pathology (01.01.2007)
Published in Ultrastructural pathology (01.01.2007)
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Journal Article
N‐Acetylcysteine does not Protect HepG2 Cells against Acetaminophen‐Induced Apoptosis
Manov, Irena, Hirsh, Mark, Iancu, Theodore C.
Published in Basic & clinical pharmacology & toxicology (01.05.2004)
Published in Basic & clinical pharmacology & toxicology (01.05.2004)
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