discovery of AZD9164, a novel muscarinic M₃ antagonist
Mete, Antonio, Bowers, Keith, Chevalier, Eric, Donald, David K, Edwards, Helen, Escott, Katherine J, Ford, Rhonan, Grime, Ken, Millichip, Ian, Teobald, Barry, Russell, Vince
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Journal Article
Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate
Furber, Mark, Tiden, Anna-Karin, Gardiner, Philip, Mete, Antonio, Ford, Rhonan, Millichip, Ian, Stein, Linda, Mather, Andrew, Kinchin, Elizabeth, Luckhurst, Christopher, Barber, Simon, Cage, Peter, Sanganee, Hitesh, Austin, Rupert, Chohan, Kamaldeep, Beri, Raj, Thong, Bob, Wallace, Alan, Oreffo, Victor, Hutchinson, Ray, Harper, Steve, Debreczeni, Judit, Breed, Jason, Wissler, Lisa, Edman, Karl
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
The discovery of AZD9164, a novel muscarinic M 3 antagonist
Mete, Antonio, Bowers, Keith, Chevalier, Eric, Donald, David K., Edwards, Helen, Escott, Katherine J., Ford, Rhonan, Grime, Ken, Millichip, Ian, Teobald, Barry, Russell, Vince
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Journal Article
Switching between agonists and antagonists at CRTh2 in a series of highly potent and selective biaryl phenoxyacetic acids
Luker, Tim, Bonnert, Roger, Schmidt, Jerzy, Sargent, Carol, Paine, Stuart W., Thom, Stephen, Pairaudeau, Gary, Patel, Anil, Mohammed, Rukhsana, Akam, Elizabeth, Dougall, Iain, Davis, Andrew M., Abbott, Phil, Brough, Steve, Millichip, Ian, McInally, Thomas
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Journal Article
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
Cheshire, David R., Åberg, Anders, Andersson, Gunilla M.K., Andrews, Glen, Beaton, Haydn G., Birkinshaw, Timothy N., Boughton-Smith, Nigel, Connolly, Stephen, Cook, Tony R., Cooper, Anne, Cooper, Sally L., Cox, David, Dixon, John, Gensmantel, Nigel, Hamley, Peter J., Harrison, Richard, Hartopp, Paul, Käck, Helena, Leeson, Paul D., Luker, Timothy, Mete, Antonio, Millichip, Ian, Nicholls, David J., Pimm, Austen D., St-Gallay, Steve A., Wallace, Alan V.
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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Journal Article
2-Aminopyridines as Highly Selective Inducible Nitric Oxide Synthase Inhibitors. Differential Binding Modes Dependent on Nitrogen Substitution
Connolly, Stephen, Aberg, Anders, Arvai, Andrew, Beaton, Haydn G, Cheshire, David R, Cook, Anthony R, Cooper, Sally, Cox, David, Hamley, Peter, Mallinder, Phil, Millichip, Ian, Nicholls, David J, Rosenfeld, Robin J, St-Gallay, Stephen A, Tainer, John, Tinker, Alan C, Wallace, Alan V
Published in Journal of medicinal chemistry (03.06.2004)
Published in Journal of medicinal chemistry (03.06.2004)
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Journal Article
9-SUBSTITUTED 8-OXOADENINE COMPOUND
WADA, HIROKI, MCINALLY, THOMAS, KURIMOTO, AYUMU, HASHIMOTO, KAZUKI, MILLICHIP, IAN, BONNERT, ROGER, ISOBE, YOSHIAKI, BROUGH, STEPHEN
Year of Publication 03.02.2016
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Year of Publication 03.02.2016
Patent
9-substituted 8-oxoadenine compound
BROUGH STEPHEN, MILLICHIP IAN, KURIMOTO AYUMU, BONNERT ROGER, MCINALLY THOMAS, HASHIMOTO KAZUKI, ISOBE YOSHIAKI, WADA HIROKI
Year of Publication 03.03.2015
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Year of Publication 03.03.2015
Patent