Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury
Rosenzweig, Ephron S., Salegio, Ernesto A., Liang, Justine J., Weber, Janet L., Weinholtz, Chase A., Brock, John H., Moseanko, Rod, Hawbecker, Stephanie, Pender, Roger, Cruzen, Christina L., Iaci, Jennifer F., Caggiano, Anthony O., Blight, Andrew R., Haenzi, Barbara, Huie, J. Russell, Havton, Leif A., Nout-Lomas, Yvette S., Fawcett, James W., Ferguson, Adam R., Beattie, Michael S., Bresnahan, Jacqueline C., Tuszynski, Mark H.
Published in Nature neuroscience (01.08.2019)
Published in Nature neuroscience (01.08.2019)
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An optimized dosing regimen of cimaglermin (neuregulin 1β3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats
Iaci, Jennifer F., Parry, Tom J., Huang, Zhihong, Pavlopoulos, Elias, Finklestein, Seth P., Ren, Jingmei, Caggiano, Anthony
Published in Journal of neuroscience research (01.03.2016)
Published in Journal of neuroscience research (01.03.2016)
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Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa)
Mosedale, Merrie, Button, Donald, Jackson, Jonathan P, Freeman, Kimberly M, Brouwer, Kenneth R, Caggiano, Anthony O, Eisen, Andrew, Iaci, Jennifer F, Parry, Tom J, Stanulis, Ric, Srinivas, Maya, Watkins, Paul B
Published in Toxicological sciences (01.02.2018)
Published in Toxicological sciences (01.02.2018)
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Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury
Sindhurakar, Anil, Mishra, Asht M, Gupta, Disha, Iaci, Jennifer F, Parry, Tom J, Carmel, Jason B
Published in Neurorehabilitation and neural repair (01.04.2017)
Published in Neurorehabilitation and neural repair (01.04.2017)
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The Evaluation of Magnesium Chloride within a Polyethylene Glycol Formulation in a Porcine Model of Acute Spinal Cord Injury
Streijger, Femke, Lee, Jae H T, Manouchehri, Neda, Okon, Elena B, Tigchelaar, Seth, Anderson, Lisa M, Dekaban, Greg A, Rudko, David A, Menon, Ravi S, Iaci, Jennifer F, Button, Donald C, Vecchione, Andrea M, Konovalov, Andrey, Sarmiere, Patrick D, Ung, Chi, Caggiano, Anthony O, Kwon, Brian K
Published in Journal of neurotrauma (15.12.2016)
Published in Journal of neurotrauma (15.12.2016)
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Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction
Parry, Tom J., Ganguly, Anindita, Troy, Erika L., Luis Guerrero, J., Iaci, Jennifer F., Srinivas, Maya, Vecchione, Andrea M., Button, Donald C., Hackett, Craig S., Zolty, Ronald, Sawyer, Douglas B., Caggiano, Anthony O.
Published in European journal of pharmacology (05.02.2017)
Published in European journal of pharmacology (05.02.2017)
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AC105 Increases Extracellular Magnesium Delivery and Reduces Excitotoxic Glutamate Exposure within Injured Spinal Cords in Rats
Huang, Zhihong, Filipovic, Zoran, Mp, Nandakumar, Ung, Chia, Troy, Erika L, Colburn, Raymond W, Iaci, Jennifer F, Hackett, Craig, Button, Donald C, Caggiano, Anthony O, Parry, Tom J
Published in Journal of neurotrauma (01.02.2017)
Published in Journal of neurotrauma (01.02.2017)
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A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure
Lenihan, Daniel J., MD, Anderson, Sarah A., ACNP, Lenneman, Carrie Geisberg, MD, Brittain, Evan, MD, MSCI, Muldowney, James A.S., MD, Mendes, Lisa, MD, Zhao, Ping Z., PhD, Iaci, Jennifer, MS, Frohwein, Stephen, MD, Zolty, Ronald, MD, PhD, Eisen, Andrew, MD, PhD, Sawyer, Douglas B., MD, PhD, Caggiano, Anthony O., MD, PhD
Published in JACC. Basic to translational science (01.12.2016)
Published in JACC. Basic to translational science (01.12.2016)
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Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction
Hill, Michael F, Patel, Amish V, Murphy, Abigail, Smith, Holly M, Galindo, Cristi L, Pentassuglia, Laura, Peng, Xuyang, Lenneman, Carrie G, Odiete, Oghenerukevwe, Friedman, David B, Kronenberg, Marvin W, Zheng, Siyuen, Zhao, Zhongming, Song, Yanna, Harrell, Jr, Frank E, Srinivas, Maya, Ganguly, Anindita, Iaci, Jennifer, Parry, Tom J, Caggiano, Anthony O, Sawyer, Douglas B
Published in PloS one (21.02.2013)
Published in PloS one (21.02.2013)
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Dalfampridine Improves Sensorimotor Function in Rats With Chronic Deficits After Middle Cerebral Artery Occlusion
Iaci, Jennifer F, Parry, Tom J, Huang, Zhihong, Finklestein, Seth P, Ren, JingMei, Barrile, Dana K, Davenport, Matthew D, Wu, Rui, Blight, Andrew R, Caggiano, Anthony O
Published in Stroke (1970) (01.07.2013)
Published in Stroke (1970) (01.07.2013)
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Glial growth factor 2 promotes functional recovery with treatment initiated up to 7 days after permanent focal ischemic stroke
Iaci, Jennifer F., Ganguly, Anindita, Finklestein, Seth P., Parry, Tom J., Ren, JingMei, Saha, Subhash, Sietsma, Dana K., Srinivas, Maya, Vecchione, Andrea M., Caggiano, Anthony O.
Published in Neuropharmacology (01.12.2010)
Published in Neuropharmacology (01.12.2010)
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748 REMOTE FROM INJURY-SITE DELIVERY OF GLIAL GROWTH FACTOR 2 (GGF2) FACILITATES RECOVERY OF ERECTILE DYSFUNCTION FOLLOWING BILATERAL CAVERNOUS NERVE INJURY IN THE RAT WITH DIRECT EVIDENCE OF CAVERNOUS NERVE PRESERVATION
Bella, Anthony J, Iaci, Jennifer F, Coderre, Elaine, Renaud, Leo P, Caggiano, Anthony O
Published in The Journal of urology (01.04.2011)
Published in The Journal of urology (01.04.2011)
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GGF2 is neuroprotective in a rat model of cavernous nerve injury-induced erectile dysfunction
Burnett, Arthur L, Sezen, Sena F, Hoke, Ahmet, Caggiano, Anthony O, Iaci, Jennifer, Lagoda, Gwen, Musicki, Biljana, Bella, Anthony J
Published in Journal of sexual medicine (01.04.2015)
Published in Journal of sexual medicine (01.04.2015)
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Abstract P345: The Neuregulin Glial Growth Factor 2 (GGF2) Produces Sustained Improvement in Left Ventricular Function in Rats with Both Early and Established Heart Failure
Ganguly, Anindita, Troy, Erika, Srinivas, Maya, Vecchione, Andrea, Sarmiere, Patrick, Hu, Tao, Iaci, Jennifer, Hackett, Craig, Button, Donald, Caggiano, Anthony, Parry, Tom J
Published in Circulation research (09.12.2011)
Published in Circulation research (09.12.2011)
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Intravenous Glial Growth Factor 2
Hill, Michael F, Patel, Amish V, Murphy, Abigail, Smith, Holly M, Galindo, Cristi L, Pentassuglia, Laura, Peng, Xuyang, Lenneman, Carrie G, Odiete, Oghenerukevwe, Friedman, David B, Kronenberg, Marvin W, Zheng, Siyuen, Zhao, Zhongming, Song, Yanna, Harrell, Frank E, Srinivas, Maya, Ganguly, Anindita, Iaci, Jennifer, Parry, Tom J, Caggiano, Anthony O, Sawyer, Douglas B
Published in PloS one (21.02.2013)
Published in PloS one (21.02.2013)
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Intravenous Glial Growth Factor 2 Isoform of Neuregulin-1[beta] Improves Left Ventricular Function, Gene and Protein Expression in Rats after Myocardial Infarction
Hill, Michael F, Patel, Amish V, Murphy, Abigail, Smith, Holly M, Galindo, Cristi L, Pentassuglia, Laura, Peng, Xuyang, Lenneman, Carrie G, Odiete, Oghenerukevwe, Friedman, David B, Kronenberg, Marvin W, Zheng, Siyuen, Zhao, Zhongming, Song, Yanna, Harrell, Frank E, Srinivas, Maya, Ganguly, Anindita, Iaci, Jennifer, Parry, Tom J, Caggiano, Anthony O, Sawyer, Douglas B
Published in PloS one (21.02.2013)
Published in PloS one (21.02.2013)
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